IL1B

gene product
IL-1B, IL1-BETA, IL1F2
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
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2223 antibodies from 45 providers.

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Novus Biologicals
217 antibodies
GeneTex
37 antibodies
R&D Systems
55 antibodies
antibodies-online
606 antibodies
Abnova Corporation
25 antibodies
Rockland Immunochemicals, Inc.
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OriGene
60 antibodies
Biorbyt
88 antibodies
Acris Antibodies GmbH
45 antibodies
Abgent
7 antibodies
LifeSpan BioSciences, Inc.
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Boster Biological Technology
7 antibodies
Aviva Systems Biology
10 antibodies
NovoPro Bioscience Inc.
10 antibodies
Affinity Biosciences
4 antibodies
NSJ Bioreagents
11 antibodies
ABEOMICS Inc.
8 antibodies
Proteintech Group
1 antibody
St John's Laboratory
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Invitrogen Antibodies
24 antibodies
Cell Signaling Technology, Inc
10 antibodies
Creative Biolabs
174 antibodies
Abbiotec
1 antibody
Bioworld Technology, Inc
2 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Creative Diagnostics
36 antibodies
GenWay
16 antibodies
ProSci
4 antibodies
Signalway Antibody LLC
1 antibody
Antibodies.com
1 antibody
BioLegend
19 antibodies
Arigo
7 antibodies
MyBioSource
37 antibodies
United States Biological
65 antibodies
Miltenyi Biotec
8 antibodies
RabMAbs
5 antibodies
Abbexa
7 antibodies
EMD Millipore
6 antibodies
Sigma-Aldrich
5 antibodies
RayBiotech, Inc.
2 antibodies
Exalpha Biologicals, Inc.
4 antibodies
eBioscience, An Affymetrix Company
13 antibodies
PeproTech Inc.
3 antibodies
Sino Biological Inc.
10 antibodies