IL1B

gene product
IL-1B, IL1-BETA, IL1F2
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
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2338 antibodies from 47 providers.

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Novus Biologicals
242 antibodies
GeneTex
37 antibodies
R&D Systems
55 antibodies
antibodies-online
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Proteintech Group
2 antibodies
Abnova Corporation
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Invitrogen Antibodies
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Rockland Immunochemicals, Inc.
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OriGene
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Biorbyt
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Acris Antibodies GmbH
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Abgent
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LifeSpan BioSciences, Inc.
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Boster Biological Technology
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Aviva Systems Biology
10 antibodies
NovoPro Bioscience Inc.
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Affinity Biosciences
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NSJ Bioreagents
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HUABIO Research
1 antibody
ABEOMICS Inc.
8 antibodies
St John's Laboratory
9 antibodies
Cell Signaling Technology, Inc
10 antibodies
Creative Biolabs
198 antibodies
Abbiotec
1 antibody
Bioworld Technology, Inc
2 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Creative Diagnostics
36 antibodies
GenWay
16 antibodies
ProSci
4 antibodies
Signalway Antibody LLC
1 antibody
PeproTech Inc.
16 antibodies
Antibodies.com
1 antibody
BioLegend
19 antibodies
Arigo
7 antibodies
MyBioSource
37 antibodies
Abbexa
24 antibodies
United States Biological
65 antibodies
Miltenyi Biotec
8 antibodies
Leading Biology
8 antibodies
RabMAbs
5 antibodies
EMD Millipore
6 antibodies
Sigma-Aldrich
5 antibodies
RayBiotech, Inc.
2 antibodies
Exalpha Biologicals, Inc.
4 antibodies
eBioscience, An Affymetrix Company
13 antibodies
Sino Biological Inc.
10 antibodies