IL1B

gene product
IL-1B, IL1-BETA, IL1F2
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
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AntibodyRefsTypeAVIWBELICCIPIHCFC
Novus Biologicals
219 antibodies
R&D Systems
43 antibodies
antibodies-online
338 antibodies
Abnova Corporation
24 antibodies
Acris Antibodies GmbH
45 antibodies
GeneTex
24 antibodies
OriGene
9 antibodies
Abgent
7 antibodies
Biorbyt
39 antibodies
LifeSpan BioSciences, Inc.
285 antibodies