Antibody data
- Antibody Data
- Antigen structure
- References [265]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 16806-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16806-1-AP, RRID:AB_10646432
- Product name
- IL-1 Beta antibody
- Antibody type
- Polyclonal
- Description
- IL-1 Beta antibody (Cat. #16806-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Injectable self-healing hydrogel with siRNA delivery property for sustained STING silencing and enhanced therapy of intervertebral disc degeneration.
Cancer-associated fibroblasts educate normal fibroblasts to facilitate cancer cell spreading and T-cell suppression.
Guizhi-Shaoyao-Zhimu decoction attenuates monosodium urate crystal-induced inflammation through inactivation of NF-κB and NLRP3 inflammasome.
F-Box Protein FBXW17-Mediated Proteasomal Degradation of Protein Methyltransferase PRMT6 Exaggerates CSE-Induced Lung Epithelial Inflammation and Apoptosis.
Traditional Chinese Medication Qiliqiangxin Attenuates Diabetic Cardiomyopathy via Activating PPARγ.
Lactobacillus acidophilus ATCC 4356 Alleviates Renal Ischemia-Reperfusion Injury Through Antioxidant Stress and Anti-inflammatory Responses and Improves Intestinal Microbial Distribution.
H2S improves doxorubicin-induced myocardial fibrosis by inhibiting oxidative stress and apoptosis via Keap1-Nrf2.
Study on Protection of Human Umbilical Vein Endothelial Cells from Amiodarone-Induced Damage by Intermedin through Activation of Wnt/β-Catenin Signaling Pathway.
Minimally Invasive Embedding of Saturated MSU Induces Persistent Gouty Arthritis in Modified Rat Model.
Dihydroartemisinin inhibits activation of the AIM2 inflammasome pathway and NF-κB/HIF-1α/VEGF pathway by inducing autophagy in A431 human cutaneous squamous cell carcinoma cells.
Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice.
KCa3.1 Inhibition of Macrophages Suppresses Inflammatory Response Leading to Endothelial Damage in a Cell Model of Kawasaki Disease.
Assessment of Pyroptosis-Related Indicators as Potential Biomarkers and Their Association with Severity in Patients with Liver Cirrhosis.
The cardioprotective effect of the sodium-glucose cotransporter 2 inhibitor dapagliflozin in rats with isoproterenol-induced cardiomyopathy.
A treatment combined prussian blue nanoparticles with low-intensity pulsed ultrasound alleviates cartilage damage in knee osteoarthritis by initiating PI3K/Akt/mTOR pathway.
AICAR, an AMP-Activated Protein Kinase Activator, Ameliorates Acute Pancreatitis-Associated Liver Injury Partially Through Nrf2-Mediated Antioxidant Effects and Inhibition of NLRP3 Inflammasome Activation.
Geniposide Combined With Notoginsenoside R1 Attenuates Inflammation and Apoptosis in Atherosclerosis via the AMPK/mTOR/Nrf2 Signaling Pathway.
Atractylodin Attenuates Dextran Sulfate Sodium-Induced Colitis by Alleviating Gut Microbiota Dysbiosis and Inhibiting Inflammatory Response Through the MAPK Pathway.
CS-semi5 Inhibits NF-κB Activation to Block Synovial Inflammation, Cartilage Loss and Bone Erosion Associated With Collagen-Induced Arthritis.
Estrogen-Related Receptor γ Agonist DY131 Ameliorates Lipopolysaccharide-Induced Acute Liver Injury.
JQ1 as a BRD4 Inhibitor Blocks Inflammatory Pyroptosis-Related Acute Colon Injury Induced by LPS.
Highly specific and label-free histological identification of microcrystals in fresh human gout tissues with stimulated Raman scattering.
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
Magnesium-L-threonate alleviate colonic inflammation and memory impairment in chronic-plus-binge alcohol feeding mice.
H2S alleviates aortic aneurysm and dissection: Crosstalk between transforming growth factor 1 signaling and NLRP3 inflammasome.
Sodium butyrate alleviates pre-eclampsia in pregnant rats by improving the gut microbiota and short-chain fatty acid metabolites production.
Anti-NAFLD Effect of Djulis Hull and Its Major Compound, Rutin, in Mice with High-Fat Diet (HFD)-Induced Obesity.
Selenomethionine alleviated Ochratoxin A induced pyroptosis and renal fibrotic factors expressions in MDCK cells.
(-)-Epicatechin ameliorates cigarette smoke-induced lung inflammation via inhibiting ROS/NLRP3 inflammasome pathway in rats with COPD.
Low-intensity pulsed ultrasound ameliorates angiotensin II-induced cardiac fibrosis by alleviating inflammation via a caveolin-1-dependent pathway.
The relationship between liver pathological inflammation degree and pyroptosis in chronic hepatitis B patients.
Regulatory roles of miRNAs 16, 133a, and 223 on osteoclastic bone destruction caused by breast cancer metastasis.
Ginsenoside Rg3 attenuates cisplatin-induced kidney injury through inhibition of apoptosis and autophagy-inhibited NLRP3.
Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury.
Protection of CAPE-pNO2 Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Indole-3-Propionic Acid, a Functional Metabolite of Clostridium sporogenes, Promotes Muscle Tissue Development and Reduces Muscle Cell Inflammation.
c-FLIP regulates pyroptosis in retinal neurons following oxygen-glucose deprivation/recovery via a GSDMD-mediated pathway.
Maternal immune activation alters adult behavior, intestinal integrity, gut microbiota and the gut inflammation.
Anti-HIV Activity of Cucurbitacin-D against Cigarette Smoke Condensate-Induced HIV Replication in the U1 Macrophages.
Resveratrol attenuates radiation enteritis through the SIRT1/FOXO3a and PI3K/AKT signaling pathways.
Restoring microRNA-499-5p Protects Sepsis-Induced Lung Injury Mice Via Targeting Sox6.
Chronic ethanol exposure induced depressive-like behavior in male C57BL/6 N mice by downregulating GluA1.
Kartogenin prevents cartilage degradation and alleviates osteoarthritis progression in mice via the miR-146a/NRF2 axis.
Cordyceps acid alleviates lung cancer in nude mice.
Gasdermin D Protects Mouse Podocytes Against High-Glucose-Induced Inflammation and Apoptosis via the C-Jun N-Terminal Kinase (JNK) Pathway.
MBD2 Mediates Septic AKI through Activation of PKCη/p38MAPK and the ERK1/2 Axis.
Therapeutic targets of rosuvastatin on heart failure and associated biological mechanisms: A study of network pharmacology and experimental validation.
Melatonin inhibits vascular endothelial cell pyroptosis by improving mitochondrial function via up-regulation and demethylation of UQCRC1.
Ameliorative effects of Schisandrin B on Schistosoma mansoni-induced hepatic fibrosis in vivo.
Renoprotective effects of levosimendan on acute kidney injury following cardiac arrest via anti-inflammation, anti-apoptosis, and ERK activation.
A neutral polysaccharide from Ophiocordyceps lanpingensis restrains cisplatin-induced nephrotoxicity.
microRNA-149-5p mediates the PM2.5-induced inflammatory response by targeting TAB2 via MAPK and NF-κB signaling pathways in vivo and in vitro.
Extracellular vesicles derived from LPS-preconditioned human synovial mesenchymal stem cells inhibit extracellular matrix degradation and prevent osteoarthritis of the knee in a mouse model.
Impaired autophagy in microglia aggravates dopaminergic neurodegeneration by regulating NLRP3 inflammasome activation in experimental models of Parkinson's disease.
Suppressing ROS generation by apocynin inhibited cyclic stretch-induced inflammatory reaction in HPDLCs via a caspase-1 dependent pathway.
Adrenomedullin Attenuates Inflammation in White Adipose Tissue of Obese Rats Through Receptor-Mediated PKA Pathway.
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Microcystin-LR Induces NLRP3 Inflammasome Activation via FOXO1 Phosphorylation, Resulting in Interleukin-1β Secretion and Pyroptosis in Hepatocytes.
Circ_0001438 participates in the pathogenesis of preeclampsia via the circ_0001438/miR-942/NLRP3 regulatory network.
Histone deacetylase 2 regulates ULK1 mediated pyroptosis during acute liver failure by the K68 acetylation site.
Adrenomedullin 2 attenuates LPS-induced inflammation in microglia cells by receptor-mediated cAMP-PKA pathway.
Silenced microRNA-222 suppresses inflammatory response in gestational diabetes mellitus mice by promoting CXCR4.
Long-term ketamine administration induces bladder damage and upregulates autophagy-associated proteins in bladder smooth muscle tissue.
Chicoric acid attenuates hyperglycemia-induced endothelial dysfunction through AMPK-dependent inhibition of oxidative/nitrative stresses.
Active components from Lagotis brachystachya maintain uric acid homeostasis by inhibiting renal TLR4-NLRP3 signaling in hyperuricemic mice.
Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.
Pik3c3 deficiency in myeloid cells imparts partial resistance to experimental autoimmune encephalomyelitis associated with reduced IL-1β production.
Isoorientin Attenuated the Pyroptotic Hepatocyte Damage Induced by Benzo[a]pyrene via ROS/NF-κB/NLRP3/Caspase-1 Signaling Pathway.
PCSK9 mediates the oxidative low‑density lipoprotein‑induced pyroptosis of vascular endothelial cells via the UQCRC1/ROS pathway.
Aspergillus fumigatus-Stimulated Human Corneal Epithelial Cells Induce Pyroptosis of THP-1 Macrophages by Secreting TSLP.
Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy.
Loss of Arf Guanine Nucleotide Exchange Factor GBF1 Activity Disturbs Organelle Dynamics in Mouse Oocytes.
CART mitigates oxidative stress and DNA damage in memory deficits of APP/PS1 mice via upregulating β‑amyloid metabolism‑associated enzymes.
Curcumin inhibits the growth of liver cancer by impairing myeloid-derived suppressor cells in murine tumor tissues.
Metformin effectively treats Tsc1 deletion-caused kidney pathology by upregulating AMPK phosphorylation.
Interleukin-1β-Induced Senescence Promotes Osteoblastic Transition of Vascular Smooth Muscle Cells.
Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells.
Protective Effects of Cinnamaldehyde against Mesenteric Ischemia-Reperfusion-Induced Lung and Liver Injuries in Rats.
La2O3 Nanoparticles Induce Reproductive Toxicity Mediated by the Nrf-2/ARE Signaling Pathway in Kunming Mice.
Blocking the LncRNA MALAT1/miR-224-5p/NLRP3 Axis Inhibits the Hippocampal Inflammatory Response in T2DM With OSA.
Detection of proteins associated with the pyroptosis signaling pathway in breast cancer tissues and their significance.
17-Allylamino-Demethoxygeldanamycin Ameliorate Microthrombosis Via HSP90/RIP3/NLRP3 Pathway After Subarachnoid Hemorrhage in Rats.
Pharmacological Inhibition of HDAC6 Attenuates NLRP3 Inflammatory Response and Protects Dopaminergic Neurons in Experimental Models of Parkinson's Disease.
Manganese Exposure Aggravates β-Amyloid Pathology by Microglial Activation.
Effect of C-phycocyanin on HDAC3 and miRNA-335 in Alzheimer's disease.
Ablation of GSDMD Improves Outcome of Ischemic Stroke Through Blocking Canonical and Non-canonical Inflammasomes Dependent Pyroptosis in Microglia.
Role of Endoplasmic Reticulum Stress in Otitis Media.
Critical Role of AdipoR1 in Regulating Th17 Cell Differentiation Through Modulation of HIF-1α-Dependent Glycolysis.
Porphyromonas gingivalis-Induced NLRP3 Inflammasome Activation and Its Downstream Interleukin-1β Release Depend on Caspase-4.
Selenomethionine Suppressed TLR4/NF-κB Pathway by Activating Selenoprotein S to Alleviate ESBL Escherichia coli-Induced Inflammation in Bovine Mammary Epithelial Cells and Macrophages.
Caffeic Acid Phenethyl Ester Prevents Colitis-Associated Cancer by Inhibiting NLRP3 Inflammasome.
Fucoidan inhibits tooth movement by promoting restorative macrophage polarization through the STAT3 pathway.
Peptidome analysis of umbilical cord mesenchymal stem cell (hUC-MSC) conditioned medium from preterm and term infants.
Monotropein alleviates secondary liver injury in chronic colitis by regulating TLR4/NF-κB signaling and NLRP3 inflammasome.
Hypertonic saline mediates the NLRP3/IL-1β signaling axis in microglia to alleviate ischemic blood-brain barrier permeability by downregulating astrocyte-derived VEGF in rats.
Trimethylamine N-oxide promotes apoE-/- mice atherosclerosis by inducing vascular endothelial cell pyroptosis via the SDHB/ROS pathway.
Protective effect of astaxanthin against La2O3 nanoparticles induced neurotoxicity by activating PI3K/AKT/Nrf-2 signaling in mice.
Transcriptomic Analysis of Age-Associated Periventricular Lesions Reveals Dysregulation of the Immune Response.
LncRNA GAS5 inhibits NLRP3 inflammasome activation-mediated pyroptosis in diabetic cardiomyopathy by targeting miR-34b-3p/AHR.
Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models.
The Differential Expression of Cytokines and Growth Factors After SMILE Compared With FS-LASIK in Rabbits.
LINC01116 promotes tumor proliferation and neutrophil recruitment via DDX5-mediated regulation of IL-1β in glioma cell.
Aging alters Hv1-mediated microglial polarization and enhances neuroinflammation after peripheral surgery.
ACPAs promote IL-1β production in rheumatoid arthritis by activating the NLRP3 inflammasome.
The Biomarker TCONS_00016233 Drives Septic AKI by Targeting the miR-22-3p/AIFM1 Signaling Axis.
Microglia polarization of hippocampus is involved in the mechanism of Apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats.
Obesity induces preadipocyte CD36 expression promoting inflammation via the disruption of lysosomal calcium homeostasis and lysosome function.
TNF-α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury.
Anti-human serum albumin autoantibody may be involved in the pathogenesis of autoimmune bullous skin diseases.
Corneal epithelial injury-induced norepinephrine promotes Pseudomonas aeruginosa keratitis.
CX3CR1-microglia mediates neuroinflammation and blood pressure regulation in the nucleus tractus solitarii of fructose-induced hypertensive rats.
Albendazole-Schisandrin B Co-Therapy on Angiostrongylus cantonensis-Induced Meningoencephalitis in Mice.
NLRP3 inflammasome-mediated microglial pyroptosis is critically involved in the development of post-cardiac arrest brain injury.
Mechanism investigation on Bisphenol S-induced oxidative stress and inflammation in murine RAW264.7 cells: The role of NLRP3 inflammasome, TLR4, Nrf2 and MAPK.
Dendrobium Alkaloids Promote Neural Function After Cerebral Ischemia-Reperfusion Injury Through Inhibiting Pyroptosis Induced Neuronal Death in both In Vivo and In Vitro Models.
α-synuclein promotes progression of Parkinson's disease by upregulating autophagy signaling pathway to activate NLRP3 inflammasome.
NR1D1 modulates synovial inflammation and bone destruction in rheumatoid arthritis.
Eicosapentaenoic acid prevents inflammation induced by acute cerebral infarction through inhibition of NLRP3 inflammasome activation.
Maresin 1 mitigates concanavalin A-induced acute liver injury in mice by inhibiting ROS-mediated activation of NF-κB signaling.
GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and NF-κB signaling pathways.
Infrapatellar fat pads participate in the development of knee osteoarthritis in obese patients via the activation of the NF‑κB signaling pathway.
A research of STEAP1 regulated gastric cancer cell proliferation, migration and invasion in vitro and in vivos.
Chronic ethanol exposure induces neuroinflammation in H4 cells through TLR3 / NF-κB pathway and anxiety-like behavior in male C57BL/6 mice.
Akkermansia muciniphila promotes type H vessel formation and bone fracture healing by reducing gut permeability and inflammation.
Angiostrongylus cantonensis activates inflammasomes in meningoencephalitic BALB/c mice.
Salvianic acid A alleviates chronic alcoholic liver disease by inhibiting HMGB1 translocation via down-regulating BRD4.
FGF21 mitigates atherosclerosis via inhibition of NLRP3 inflammasome-mediated vascular endothelial cells pyroptosis.
Salidroside Decreases Atherosclerosis Plaque Formation via Inhibiting Endothelial Cell Pyroptosis.
Inhibition of the ox-LDL-Induced Pyroptosis by FGF21 of Human Umbilical Vein Endothelial Cells Through the TET2-UQCRC1-ROS Pathway.
COMP in the Infrapatellar Fat Pad-Results of a Prospective Histological, Immunohistological, and Biochemical Case-Control Study.
High- and low-virulent bovine Pasteurella multocida induced differential NLRP3 inflammasome activation and subsequent IL-1β secretion.
p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species.
Antitumor Effects of Berberine on Gliomas via Inactivation of Caspase-1-Mediated IL-1β and IL-18 Release.
NLRP3 Inflammasome Is Involved in Calcium-Sensing Receptor-Induced Aortic Remodeling in SHRs.
Purple Sweet Potato Color Attenuates Kidney Damage by Blocking VEGFR2/ROS/NLRP3 Signaling in High-Fat Diet-Treated Mice.
Hydrogen Inhalation Attenuates Oxidative Stress Related Endothelial Cells Injury After Subarachnoid Hemorrhage in Rats.
Sorghum Phenolics Inhibits Inflammasomes in Lipopolysaccharide (LPS)-Primed and Adenosine Triphosphate (ATP)-Activated Macrophages.
Vaccaria n-Butanol Extract Lower the Production of Proinflammatory Cytokines and the Infection Risk of T. spiralis In Vivo.
Hydrogen inhalation protects hypoxic-ischemic brain damage by attenuating inflammation and apoptosis in neonatal rats.
TAK242 suppresses the TLR4 signaling pathway and ameliorates DCD liver IRI in rats.
MiR-143-3p directly targets GLUT9 to reduce uric acid reabsorption and inflammatory response of renal tubular epithelial cells.
Upregulation of miR-93 and inhibition of LIMK1 improve ventricular remodeling and alleviate cardiac dysfunction in rats with chronic heart failure by inhibiting RhoA/ROCK signaling pathway activation.
Migratory Neural Crest Cells Phagocytose Dead Cells in the Developing Nervous System.
Pyroptosis engagement and bladder urothelial cell-derived exosomes recruit mast cells and induce barrier dysfunction of bladder urothelium after uropathogenic E. coli infection.
LncRNA HIF1A-AS1 contributes to ventricular remodeling after myocardial ischemia/reperfusion injury by adsorption of microRNA-204 to regulating SOCS2 expression.
Curcumin attenuates potassium oxonate-induced hyperuricemia and kidney inflammation in mice.
IMM-H007, a novel small molecule inhibitor for atherosclerosis, represses endothelium inflammation by regulating the activity of NF-κB and JNK/AP1 signaling.
SETD7 mediates spinal microgliosis and neuropathic pain in a rat model of peripheral nerve injury.
Akt inhibitor deguelin aggravates inflammation and fibrosis in myocarditis.
Iguratimod (T-614) attenuates severe acute pancreatitis by inhibiting the NLRP3 inflammasome and NF-κB pathway.
Ameliorative effects of echinacoside against spinal cord injury via inhibiting NLRP3 inflammasome signaling pathway.
Gender Difference in Damage-Mediated Signaling Contributes to Pulmonary Arterial Hypertension.
OxLDL induces vascular endothelial cell pyroptosis through miR-125a-5p/TET2 pathway.
Purple sweet potato color attenuated NLRP3 inflammasome by inducing autophagy to delay endothelial senescence.
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
Tougu Xiaotong capsule exerts a therapeutic effect on knee osteoarthritis by regulating subchondral bone remodeling.
Sweroside Alleviated LPS-Induced Inflammation via SIRT1 Mediating NF-κB and FOXO1 Signaling Pathways in RAW264.7 Cells.
Caspase-11 promotes renal fibrosis by stimulating IL-1β maturation via activating caspase-1.
Clock mutant promotes osteoarthritis by inhibiting the acetylation of NFκB.
STING-IRF3 contributes to lipopolysaccharide-induced cardiac dysfunction, inflammation, apoptosis and pyroptosis by activating NLRP3.
An NLRP3 inflammasome-triggered cytokine storm contributes to Streptococcal toxic shock-like syndrome (STSLS).
Chitosan Hydrogel Delivery System Containing Herbal Compound Functions as a Potential Antineuroinflammatory Agent.
NLRP3 inflammasome activates interleukin-23/interleukin-17 axis during ischaemia-reperfusion injury in cerebral ischaemia in mice.
Helicobacter pylori-induced YAP1 nuclear translocation promotes gastric carcinogenesis by enhancing IL-1β expression.
Pioglitazone decreased renal calcium oxalate crystal formation by suppressing M1 macrophage polarization via the PPAR-γ-miR-23 axis.
The synergistic effect of NOD2 and TLR4 on the activation of autophagy in human submandibular gland inflammation.
OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice.
Relationship between serum IL-1β and insomnia and liver depression in patients with perimenopausal non-organic sleep disorder.
LXRα promotes cell metastasis by regulating the NLRP3 inflammasome in renal cell carcinoma.
Juxtaposition of IL-1β and IFN-γ expression and apoptosis of keratinocytes in adult-onset Still's disease.
Differential immune responses of C57BL/6 mice to infection by Salmonella enterica serovar Typhimurium strain SL1344, CVCC541 and CMCC50115.
Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway.
Liraglutide ameliorates non-alcoholic steatohepatitis by inhibiting NLRP3 inflammasome and pyroptosis activation via mitophagy.
Schwann cell transplantation exerts neuroprotective roles in rat model of spinal cord injury by combating inflammasome activation and improving motor recovery and remyelination.
Bacteroides fragilis Strain ZY-312 Defense against Cronobacter sakazakii-Induced Necrotizing Enterocolitis In Vitro and in a Neonatal Rat Model.
Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure.
Berberine inhibits NLRP3 Inflammasome pathway in human triple-negative breast cancer MDA-MB-231 cell.
Gasdermin-d Played a Critical Role in the Cyclic Stretch-Induced Inflammatory Reaction in Human Periodontal Ligament Cells.
Role of Thymoquinone in Cardiac Damage Caused by Sepsis from BALB/c Mice.
NLRP3 inflammasome plays an important role in caspase-1 activation and IL-1β secretion in macrophages infected with Pasteurella multocida.
Protective effects of ginsenoside Rk3 against chronic alcohol-induced liver injury in mice through inhibition of inflammation, oxidative stress, and apoptosis.
Directed self-assembly of herbal small molecules into sustained release hydrogels for treating neural inflammation.
The Anticonvulsant Effects of Baldrinal on Pilocarpine-Induced convulsion in Adult Male Mice.
Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Omentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines.
Methane-Rich Saline Ameliorates Sepsis-Induced Acute Kidney Injury through Anti-Inflammation, Antioxidative, and Antiapoptosis Effects by Regulating Endoplasmic Reticulum Stress.
Expression and clinical significance of the NEK7-NLRP3 inflammasome signaling pathway in patients with systemic lupus erythematosus.
Inhibition of Heat Shock Protein 90 by 17-AAG Reduces Inflammation via P2X7 Receptor/NLRP3 Inflammasome Pathway and Increases Neurogenesis After Subarachnoid Hemorrhage in Mice.
Combination Treatment of Icariin and L-DOPA Against 6-OHDA-Lesioned Dopamine Neurotoxicity.
NADH protect against radiation enteritis by enhancing autophagy and inhibiting inflammation through PI3K/AKT pathway.
Naringin Dihydrochalcone Ameliorates Cognitive Deficits and Neuropathology in APP/PS1 Transgenic Mice.
Casticin prevents DSS induced ulcerative colitis in mice through inhibitions of NF-κB pathway and ROS signaling.
Tumour YAP1 and PTEN expression correlates with tumour-associated myeloid suppressor cell expansion and reduced survival in colorectal cancer.
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration.
Lysyl oxidase blockade ameliorates anovulation in polycystic ovary syndrome.
Autocrine IL-1β mediates the promotion of corneal neovascularization by senescent fibroblasts.
Protective effects of mitochondrion-targeted peptide SS-31 against hind limb ischemia-reperfusion injury.
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.
Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells.
The role of the microRNA-146a/complement factor H/interleukin-1β-mediated inflammatory loop circuit in the perpetuate inflammation of chronic temporal lobe epilepsy.
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Carbon monoxide-releasing molecule-3 protects against ischemic stroke by suppressing neuroinflammation and alleviating blood-brain barrier disruption.
Role of Brain-Derived Neurotrophic Factor in Endometriosis Pain.
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Effects of Dandelion Extract on the Proliferation of Rat Skeletal Muscle Cells and the Inhibition of a Lipopolysaccharide-Induced Inflammatory Reaction.
Prenatal cold stress: Effect on maternal hippocampus and offspring behavior in rats.
Hydrogen sulfide protects neonatal rat medulla oblongata against prenatal cigarette smoke exposure via anti-oxidative and anti-inflammatory effects.
Curcumin Attenuates Colistin-Induced Neurotoxicity in N2a Cells via Anti-inflammatory Activity, Suppression of Oxidative Stress, and Apoptosis.
Vaccarin alleviates hypertension and nephropathy in renovascular hypertensive rats.
Surgical incision induces learning impairment in mice partially through inhibition of the brain-derived neurotrophic factor signaling pathway in the hippocampus and amygdala.
Mechanism of salvianolic acid B neuroprotection against ischemia/reperfusion induced cerebral injury.
NF-E2-Related Factor 2 Suppresses Intestinal Fibrosis by Inhibiting Reactive Oxygen Species-Dependent TGF-β1/SMADs Pathway.
Telbivudine attenuates UUO-induced renal fibrosis via TGF-β/Smad and NF-κB signaling.
Fungal β-Glucan Activates the NLRP3 Inflammasome in Human Bronchial Epithelial Cells Through ROS Production.
Effects of platelet-rich plasma on the activity of human menstrual blood-derived stromal cells in vitro.
Pyroptosis induced by enterovirus 71 and coxsackievirus B3 infection affects viral replication and host response.
CAPE-pNO2 attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice.
Influence of vitamin D deficiency on T cell subsets and related indices during spinal tuberculosis.
Proteomic profiling of human decidual immune proteins during Toxoplasma gondii infection.
Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice.
Fenofibrate Exerts Protective Effects in Diabetic Retinopathy via Inhibition of the ANGPTL3 Pathway.
Establishment of experimental autoimmune prostatitis model by T2 peptide in aluminium hydroxide adjuvant.
Tumor-Stroma IL1β-IRAK4 Feedforward Circuitry Drives Tumor Fibrosis, Chemoresistance, and Poor Prognosis in Pancreatic Cancer.
Aliskiren Improves Ischemia- and Oxygen Glucose Deprivation-Induced Cardiac Injury through Activation of Autophagy and AMP-Activated Protein Kinase.
NLRP3 Gene Deletion Attenuates Angiotensin II-Induced Phenotypic Transformation of Vascular Smooth Muscle Cells and Vascular Remodeling.
Salusin-β Is Involved in Diabetes Mellitus-Induced Endothelial Dysfunction via Degradation of Peroxisome Proliferator-Activated Receptor Gamma.
Adulthood Exposure to Lipopolysaccharide Exacerbates the Neurotoxic and Inflammatory Effects of Rotenone in the Substantia Nigra.
GRP78 plays an integral role in tumor cell inflammation-related migration induced by M2 macrophages.
Melatonin attenuated the brain damage and cognitive impairment partially through MT2 melatonin receptor in mice with chronic cerebral hypoperfusion.
NLRP3 inflammasome activation contributes to VSMC phenotypic transformation and proliferation in hypertension.
Role of NF-κB/GATA3 in the inhibition of lysyl oxidase by IL-1β in human amnion fibroblasts.
Neuroprotective Effect of Chitosan Oligosaccharide on Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.
Suppression of MyD88-dependent signaling alleviates neuropathic pain induced by peripheral nerve injury in the rat.
Naoling decoction restores cognitive function by inhibiting the neuroinflammatory network in a rat model of Alzheimer's disease.
Global Transcriptomic Profiling of Cortex and Striatum: Cerebral Injury after Ischemia/Reperfusion in a Mouse Model.
Rapamycin suppresses Aβ25-35- or LPS-induced neuronal inflammation via modulation of NF-κB signaling.
Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells.
Dopamine D2 receptor signalling controls inflammation in acute pancreatitis via a PP2A-dependent Akt/NF-κB signalling pathway.
Impact of prenatal cold stress on placental physiology, inflammatory response, and apoptosis in rats.
Possible involvement of the oxLDL/LOX-1 system in the pathogenesis and progression of human intervertebral disc degeneration or herniation.
Rapid allergen-induced interleukin-17 and interferon-γ secretion by skin-resident memory CD8+ T cells.
Inflammatory Stress Sensitizes the Liver to Atorvastatin-Induced Injury in ApoE-/- Mice.
A recombinant TGF-β1 vaccine ameliorates diabetic nephropathy in OLETF rats.
15d-PGJ2 alleviates ConA-induced acute liver injury in mice by up-regulating HO-1 and reducing hepatic cell autophagy.
Histone deacetylase inhibitor SAHA attenuates post-seizure hippocampal microglia TLR4/MYD88 signaling and inhibits TLR4 gene expression via histone acetylation.
New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats.
Dendrobium officinale Kimura et Migo attenuates diabetic cardiomyopathy through inhibiting oxidative stress, inflammation and fibrosis in streptozotocin-induced mice.
Angiotensin(1-7) attenuated Angiotensin II-induced hepatocyte EMT by inhibiting NOX-derived H2O2-activated NLRP3 inflammasome/IL-1β/Smad circuit.
The quantum of initial transformed cells potentially modulates the type of local inflammation mechanism elicited by surrounding normal epithelial tissues and systemic immune pattern for tumor arrest or progression.
Expression of beclin-1 in the microenvironment of invasive ductal carcinoma of the breast: correlation with prognosis and the cancer-stromal interaction.
Inhibition of HMGB1 release via salvianolic acid B-mediated SIRT1 up-regulation protects rats against non-alcoholic fatty liver disease.
P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation.
Aging increases the susceptibility of cisplatin-induced nephrotoxicity.
Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.
Impaired autophagy contributes to adverse cardiac remodeling in acute myocardial infarction.
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Mulberroside A protects against ischemic impairment in primary culture of rat cortical neurons after oxygen-glucose deprivation followed by reperfusion.
Tongxinluo inhibits vascular inflammation and neointimal hyperplasia through blockade of the positive feedback loop between miR-155 and TNF-α.
Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation.
NDGA reduces secondary damage after spinal cord injury in rats via anti-inflammatory effects.
Chen J, Zhu H, Zhu Y, Zhao C, Wang S, Zheng Y, Xie Z, Jin Y, Song H, Yang L, Zhang J, Dai J, Hu Z, Wang H
Bioactive materials 2022 Mar;9:29-43
Bioactive materials 2022 Mar;9:29-43
Cancer-associated fibroblasts educate normal fibroblasts to facilitate cancer cell spreading and T-cell suppression.
Itoh G, Takagane K, Fukushi Y, Kuriyama S, Umakoshi M, Goto A, Yanagihara K, Yashiro M, Tanaka M
Molecular oncology 2022 Jan;16(1):166-187
Molecular oncology 2022 Jan;16(1):166-187
Guizhi-Shaoyao-Zhimu decoction attenuates monosodium urate crystal-induced inflammation through inactivation of NF-κB and NLRP3 inflammasome.
Zhou GQ, Chen G, Yang J, Qin WY, Ping J
Journal of ethnopharmacology 2022 Jan 30;283:114707
Journal of ethnopharmacology 2022 Jan 30;283:114707
F-Box Protein FBXW17-Mediated Proteasomal Degradation of Protein Methyltransferase PRMT6 Exaggerates CSE-Induced Lung Epithelial Inflammation and Apoptosis.
Li T, He X, Luo L, Zeng H, Ren S, Chen Y
Frontiers in cell and developmental biology 2021;9:599020
Frontiers in cell and developmental biology 2021;9:599020
Traditional Chinese Medication Qiliqiangxin Attenuates Diabetic Cardiomyopathy via Activating PPARγ.
Wu X, Zhang T, Lyu P, Chen M, Ni G, Cheng H, Xu G, Li X, Wang L, Shang H
Frontiers in cardiovascular medicine 2021;8:698056
Frontiers in cardiovascular medicine 2021;8:698056
Lactobacillus acidophilus ATCC 4356 Alleviates Renal Ischemia-Reperfusion Injury Through Antioxidant Stress and Anti-inflammatory Responses and Improves Intestinal Microbial Distribution.
Zhang P, Han X, Zhang X, Zhu X
Frontiers in nutrition 2021;8:667695
Frontiers in nutrition 2021;8:667695
H2S improves doxorubicin-induced myocardial fibrosis by inhibiting oxidative stress and apoptosis via Keap1-Nrf2.
Li Y, Chandra TP, Song X, Nie L, Liu M, Yi J, Zheng X, Chu C, Yang J
Technology and health care : official journal of the European Society for Engineering and Medicine 2021;29(S1):195-209
Technology and health care : official journal of the European Society for Engineering and Medicine 2021;29(S1):195-209
Study on Protection of Human Umbilical Vein Endothelial Cells from Amiodarone-Induced Damage by Intermedin through Activation of Wnt/β-Catenin Signaling Pathway.
Wang Y, Wang J, Yang J, Kang J, Xue F, Chang S, Ji H, Zang H, Zhou X, Wang G, Fan W, Yan X, Guo J, Ren X, Tian J
Oxidative medicine and cellular longevity 2021;2021:8889408
Oxidative medicine and cellular longevity 2021;2021:8889408
Minimally Invasive Embedding of Saturated MSU Induces Persistent Gouty Arthritis in Modified Rat Model.
Xu HL, Li SK, Xue XA, Chen ZY, Hua YH
BioMed research international 2021;2021:6641701
BioMed research international 2021;2021:6641701
Dihydroartemisinin inhibits activation of the AIM2 inflammasome pathway and NF-κB/HIF-1α/VEGF pathway by inducing autophagy in A431 human cutaneous squamous cell carcinoma cells.
Wang Y, Li Z, Teng M, Liu J
International journal of medical sciences 2021;18(12):2705-2715
International journal of medical sciences 2021;18(12):2705-2715
Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice.
Chang Y, Yao Y, Ma R, Wang Z, Hu J, Wu Y, Jiang X, Li L, Li G
Frontiers in neuroscience 2021;15:620176
Frontiers in neuroscience 2021;15:620176
KCa3.1 Inhibition of Macrophages Suppresses Inflammatory Response Leading to Endothelial Damage in a Cell Model of Kawasaki Disease.
Zheng F, Tao Y, Liu J, Geng Z, Wang Y, Wang Y, Fu S, Wang W, Xie C, Zhang Y, Gong F
Journal of inflammation research 2021;14:719-735
Journal of inflammation research 2021;14:719-735
Assessment of Pyroptosis-Related Indicators as Potential Biomarkers and Their Association with Severity in Patients with Liver Cirrhosis.
Wang D, Zhan X, Wu R, You Y, Chen W, Duan L
Journal of inflammation research 2021;14:3185-3196
Journal of inflammation research 2021;14:3185-3196
The cardioprotective effect of the sodium-glucose cotransporter 2 inhibitor dapagliflozin in rats with isoproterenol-induced cardiomyopathy.
Wang FZ, Wei WB, Li X, Huo JY, Jiang WY, Wang HY, Qian P, Li ZZ, Zhou YB
American journal of translational research 2021;13(9):10950-10961
American journal of translational research 2021;13(9):10950-10961
A treatment combined prussian blue nanoparticles with low-intensity pulsed ultrasound alleviates cartilage damage in knee osteoarthritis by initiating PI3K/Akt/mTOR pathway.
Zuo D, Tan B, Jia G, Wu D, Yu L, Jia L
American journal of translational research 2021;13(5):3987-4006
American journal of translational research 2021;13(5):3987-4006
AICAR, an AMP-Activated Protein Kinase Activator, Ameliorates Acute Pancreatitis-Associated Liver Injury Partially Through Nrf2-Mediated Antioxidant Effects and Inhibition of NLRP3 Inflammasome Activation.
Kong L, Zhang H, Lu C, Shi K, Huang H, Zheng Y, Wang Y, Wang D, Wang H, Huang W
Frontiers in pharmacology 2021;12:724514
Frontiers in pharmacology 2021;12:724514
Geniposide Combined With Notoginsenoside R1 Attenuates Inflammation and Apoptosis in Atherosclerosis via the AMPK/mTOR/Nrf2 Signaling Pathway.
Liu X, Xu Y, Cheng S, Zhou X, Zhou F, He P, Hu F, Zhang L, Chen Y, Jia Y
Frontiers in pharmacology 2021;12:687394
Frontiers in pharmacology 2021;12:687394
Atractylodin Attenuates Dextran Sulfate Sodium-Induced Colitis by Alleviating Gut Microbiota Dysbiosis and Inhibiting Inflammatory Response Through the MAPK Pathway.
Qu L, Lin X, Liu C, Ke C, Zhou Z, Xu K, Cao G, Liu Y
Frontiers in pharmacology 2021;12:665376
Frontiers in pharmacology 2021;12:665376
CS-semi5 Inhibits NF-κB Activation to Block Synovial Inflammation, Cartilage Loss and Bone Erosion Associated With Collagen-Induced Arthritis.
Li X, Tang X, Wang Y, Chai C, Zhao Z, Zhang H, Peng Y, Wu L
Frontiers in pharmacology 2021;12:655101
Frontiers in pharmacology 2021;12:655101
Estrogen-Related Receptor γ Agonist DY131 Ameliorates Lipopolysaccharide-Induced Acute Liver Injury.
Ma H, Liu J, Du Y, Zhang S, Cao W, Jia Z, Gong W, Zhang A
Frontiers in pharmacology 2021;12:626166
Frontiers in pharmacology 2021;12:626166
JQ1 as a BRD4 Inhibitor Blocks Inflammatory Pyroptosis-Related Acute Colon Injury Induced by LPS.
Chen L, Zhong X, Cao W, Mao M, Li W, Yang H, Li M, Shi M, Zhang Y, Deng Y, Zu X, Liu J
Frontiers in immunology 2021;12:609319
Frontiers in immunology 2021;12:609319
Highly specific and label-free histological identification of microcrystals in fresh human gout tissues with stimulated Raman scattering.
Zhang B, Xu H, Chen J, Zhu X, Xue Y, Yang Y, Ao J, Hua Y, Ji M
Theranostics 2021;11(7):3074-3088
Theranostics 2021;11(7):3074-3088
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
Tang B, Song M, Xie X, Le D, Tu Q, Wu X, Chen M
Neurochemical research 2021 Sep;46(9):2387-2402
Neurochemical research 2021 Sep;46(9):2387-2402
Magnesium-L-threonate alleviate colonic inflammation and memory impairment in chronic-plus-binge alcohol feeding mice.
Liu C, Cheng Y, Guo Y, Qian H
Brain research bulletin 2021 Sep;174:184-193
Brain research bulletin 2021 Sep;174:184-193
H2S alleviates aortic aneurysm and dissection: Crosstalk between transforming growth factor 1 signaling and NLRP3 inflammasome.
Cui J, Xu G, Bian F
International journal of cardiology 2021 Sep 1;338:215-225
International journal of cardiology 2021 Sep 1;338:215-225
Sodium butyrate alleviates pre-eclampsia in pregnant rats by improving the gut microbiota and short-chain fatty acid metabolites production.
Yong W, Zhao Y, Jiang X, Li P
Journal of applied microbiology 2021 Sep 1;
Journal of applied microbiology 2021 Sep 1;
Anti-NAFLD Effect of Djulis Hull and Its Major Compound, Rutin, in Mice with High-Fat Diet (HFD)-Induced Obesity.
Tung YT, Zeng JL, Ho ST, Xu JW, Li S, Wu JH
Antioxidants (Basel, Switzerland) 2021 Oct 27;10(11)
Antioxidants (Basel, Switzerland) 2021 Oct 27;10(11)
Selenomethionine alleviated Ochratoxin A induced pyroptosis and renal fibrotic factors expressions in MDCK cells.
Mao X, Li H, Ge L, Liu S, Hou L, Yue D, Du H, Pan C, Gan F, Liu Y, Huang K, Chen X
Journal of biochemical and molecular toxicology 2021 Oct 21;:e22933
Journal of biochemical and molecular toxicology 2021 Oct 21;:e22933
(-)-Epicatechin ameliorates cigarette smoke-induced lung inflammation via inhibiting ROS/NLRP3 inflammasome pathway in rats with COPD.
Tian X, Xue Y, Xie G, Zhou Y, Xiao H, Ding F, Zhang M
Toxicology and applied pharmacology 2021 Oct 15;429:115674
Toxicology and applied pharmacology 2021 Oct 15;429:115674
Low-intensity pulsed ultrasound ameliorates angiotensin II-induced cardiac fibrosis by alleviating inflammation via a caveolin-1-dependent pathway.
Zhao K, Zhang J, Xu T, Yang C, Weng L, Wu T, Wu X, Miao J, Guo X, Tu J, Zhang D, Zhou B, Sun W, Kong X
Journal of Zhejiang University. Science. B 2021 Oct 15;22(10):818-838
Journal of Zhejiang University. Science. B 2021 Oct 15;22(10):818-838
The relationship between liver pathological inflammation degree and pyroptosis in chronic hepatitis B patients.
Wang Y, Li X, Chen Q, Jiao F, Shi C, Pei M, Wang L, Gong Z
Journal of medical virology 2021 Nov;93(11):6229-6235
Journal of medical virology 2021 Nov;93(11):6229-6235
Regulatory roles of miRNAs 16, 133a, and 223 on osteoclastic bone destruction caused by breast cancer metastasis.
Kitayama K, Kawamoto T, Kawakami Y, Hara H, Takemori T, Fujiwara S, Yahiro S, Miyamoto T, Mifune Y, Hoshino Y, Kakutani K, Matsumoto T, Matsushita T, Niikura T, Kuroda R, Akisue T
International journal of oncology 2021 Nov;59(5)
International journal of oncology 2021 Nov;59(5)
Ginsenoside Rg3 attenuates cisplatin-induced kidney injury through inhibition of apoptosis and autophagy-inhibited NLRP3.
Zhai J, Gao H, Wang S, Zhang S, Qu X, Zhang Y, Tao L, Sun J, Song Y, Fu L
Journal of biochemical and molecular toxicology 2021 Nov;35(11):e22896
Journal of biochemical and molecular toxicology 2021 Nov;35(11):e22896
Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury.
Wang L, Kong L, Xu S, Wang X, Huang K, Wang S, Wu J, Wang C, Sun H, Liu K, Meng Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Nov 5;:153845
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Nov 5;:153845
Protection of CAPE-pNO2 Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Wan Q, Zhang L, Zhou Q, Han Y, Li Z, Li B
Inflammation 2021 Nov 24;
Inflammation 2021 Nov 24;
Indole-3-Propionic Acid, a Functional Metabolite of Clostridium sporogenes, Promotes Muscle Tissue Development and Reduces Muscle Cell Inflammation.
Du L, Qi R, Wang J, Liu Z, Wu Z
International journal of molecular sciences 2021 Nov 18;22(22)
International journal of molecular sciences 2021 Nov 18;22(22)
c-FLIP regulates pyroptosis in retinal neurons following oxygen-glucose deprivation/recovery via a GSDMD-mediated pathway.
Huang Y, Wang S, Huang F, Zhang Q, Qin B, Liao L, Wang M, Wan H, Yan W, Chen D, Liu F, Jiang B, Ji D, Xia X, Huang J, Xiong K
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2021 May;235:151672
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2021 May;235:151672
Maternal immune activation alters adult behavior, intestinal integrity, gut microbiota and the gut inflammation.
Li W, Chen M, Feng X, Song M, Shao M, Yang Y, Zhang L, Liu Q, Lv L, Su X
Brain and behavior 2021 May;11(5):e02133
Brain and behavior 2021 May;11(5):e02133
Anti-HIV Activity of Cucurbitacin-D against Cigarette Smoke Condensate-Induced HIV Replication in the U1 Macrophages.
Kodidela S, Sinha N, Kumar A, Kumar S
Viruses 2021 May 27;13(6)
Viruses 2021 May 27;13(6)
Resveratrol attenuates radiation enteritis through the SIRT1/FOXO3a and PI3K/AKT signaling pathways.
Qin H, Zhang H, Zhang X, Zhang S, Zhu S, Wang H
Biochemical and biophysical research communications 2021 May 21;554:199-205
Biochemical and biophysical research communications 2021 May 21;554:199-205
Restoring microRNA-499-5p Protects Sepsis-Induced Lung Injury Mice Via Targeting Sox6.
Zhang W, Li J, Yao H, Li T
Nanoscale research letters 2021 May 21;16(1):89
Nanoscale research letters 2021 May 21;16(1):89
Chronic ethanol exposure induced depressive-like behavior in male C57BL/6 N mice by downregulating GluA1.
Yao H, Shen H, Yu H, Wang C, Ding R, Lan X, Tash D, Wu X, Wang X, Zhang G
Physiology & behavior 2021 May 15;234:113387
Physiology & behavior 2021 May 15;234:113387
Kartogenin prevents cartilage degradation and alleviates osteoarthritis progression in mice via the miR-146a/NRF2 axis.
Hou M, Zhang Y, Zhou X, Liu T, Yang H, Chen X, He F, Zhu X
Cell death & disease 2021 May 13;12(5):483
Cell death & disease 2021 May 13;12(5):483
Cordyceps acid alleviates lung cancer in nude mice.
Wang J, Chen H, Li W, Shan L
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22670
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22670
Gasdermin D Protects Mouse Podocytes Against High-Glucose-Induced Inflammation and Apoptosis via the C-Jun N-Terminal Kinase (JNK) Pathway.
Li H, Zhao K, Li Y
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 9;27:e928411
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 9;27:e928411
MBD2 Mediates Septic AKI through Activation of PKCη/p38MAPK and the ERK1/2 Axis.
Xie Y, Liu B, Pan J, Liu J, Li X, Li H, Qiu S, Xiang X, Zheng P, Chen J, Yuan Y, Dong Z, Zhang D
Molecular therapy. Nucleic acids 2021 Mar 5;23:76-88
Molecular therapy. Nucleic acids 2021 Mar 5;23:76-88
Therapeutic targets of rosuvastatin on heart failure and associated biological mechanisms: A study of network pharmacology and experimental validation.
Lian Z, Song JX, Yu SR, Su LN, Cui YX, Li SF, Lee CY, Liang HZ, Chen H
European journal of pharmacology 2021 Mar 15;895:173888
European journal of pharmacology 2021 Mar 15;895:173888
Melatonin inhibits vascular endothelial cell pyroptosis by improving mitochondrial function via up-regulation and demethylation of UQCRC1.
Zeng J, Tao J, Xia L, Zeng Z, Chen J, Wang Z, Meng J, Liu L
Biochemistry and cell biology = Biochimie et biologie cellulaire 2021 Jun;99(3):339-347
Biochemistry and cell biology = Biochimie et biologie cellulaire 2021 Jun;99(3):339-347
Ameliorative effects of Schisandrin B on Schistosoma mansoni-induced hepatic fibrosis in vivo.
Lam HYP, Liang TR, Peng SY
PLoS neglected tropical diseases 2021 Jun;15(6):e0009554
PLoS neglected tropical diseases 2021 Jun;15(6):e0009554
Renoprotective effects of levosimendan on acute kidney injury following cardiac arrest via anti-inflammation, anti-apoptosis, and ERK activation.
Tian L, Wang S, Zhao L, Lu X, Zhu C, Gong H, Yang W
FEBS open bio 2021 Jun 11;
FEBS open bio 2021 Jun 11;
A neutral polysaccharide from Ophiocordyceps lanpingensis restrains cisplatin-induced nephrotoxicity.
Zhou S, Zhou Y, Yu J, Jiang L, Xiang Y, Wang J, Du Y, Cui X, Ge F
Food science & nutrition 2021 Jul;9(7):3602-3616
Food science & nutrition 2021 Jul;9(7):3602-3616
microRNA-149-5p mediates the PM2.5-induced inflammatory response by targeting TAB2 via MAPK and NF-κB signaling pathways in vivo and in vitro.
Li Q, Li S, Xu C, Zhao J, Hou L, Jiang F, Zhu Z, Wang Y, Tian L
Cell biology and toxicology 2021 Jul 31;
Cell biology and toxicology 2021 Jul 31;
Extracellular vesicles derived from LPS-preconditioned human synovial mesenchymal stem cells inhibit extracellular matrix degradation and prevent osteoarthritis of the knee in a mouse model.
Duan A, Shen K, Li B, Li C, Zhou H, Kong R, Shao Y, Qin J, Yuan T, Ji J, Guo W, Wang X, Xue T, Li L, Huang X, Sun Y, Cai Z, Liu W, Liu F
Stem cell research & therapy 2021 Jul 28;12(1):427
Stem cell research & therapy 2021 Jul 28;12(1):427
Impaired autophagy in microglia aggravates dopaminergic neurodegeneration by regulating NLRP3 inflammasome activation in experimental models of Parkinson's disease.
Qin Y, Qiu J, Wang P, Liu J, Zhao Y, Jiang F, Lou H
Brain, behavior, and immunity 2021 Jan;91:324-338
Brain, behavior, and immunity 2021 Jan;91:324-338
Suppressing ROS generation by apocynin inhibited cyclic stretch-induced inflammatory reaction in HPDLCs via a caspase-1 dependent pathway.
Wang Y, Song Y, Zhong Q, Wu Y, Zhuang J, Qu F, Xu C
International immunopharmacology 2021 Jan;90:107129
International immunopharmacology 2021 Jan;90:107129
Adrenomedullin Attenuates Inflammation in White Adipose Tissue of Obese Rats Through Receptor-Mediated PKA Pathway.
Dai HB, Wang FZ, Kang Y, Sun J, Zhou H, Gao Q, Li ZZ, Qian P, Zhu GQ, Zhou YB
Obesity (Silver Spring, Md.) 2021 Jan;29(1):86-97
Obesity (Silver Spring, Md.) 2021 Jan;29(1):86-97
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Tian D, Teng X, Jin S, Chen Y, Xue H, Xiao L, Wu Y
Journal of advanced research 2021 Jan;27:115-125
Journal of advanced research 2021 Jan;27:115-125
Microcystin-LR Induces NLRP3 Inflammasome Activation via FOXO1 Phosphorylation, Resulting in Interleukin-1β Secretion and Pyroptosis in Hepatocytes.
Zhang Y, Zhu P, Wu X, Yuan T, Su Z, Chen S, Zhou Y, Tao WA
Toxicological sciences : an official journal of the Society of Toxicology 2021 Jan 6;179(1):53-69
Toxicological sciences : an official journal of the Society of Toxicology 2021 Jan 6;179(1):53-69
Circ_0001438 participates in the pathogenesis of preeclampsia via the circ_0001438/miR-942/NLRP3 regulatory network.
Li X, Yang R, Xu Y, Zhang Y
Placenta 2021 Jan 15;104:40-50
Placenta 2021 Jan 15;104:40-50
Histone deacetylase 2 regulates ULK1 mediated pyroptosis during acute liver failure by the K68 acetylation site.
Wang Y, Chen Q, Jiao F, Shi C, Pei M, Wang L, Gong Z
Cell death & disease 2021 Jan 11;12(1):55
Cell death & disease 2021 Jan 11;12(1):55
Adrenomedullin 2 attenuates LPS-induced inflammation in microglia cells by receptor-mediated cAMP-PKA pathway.
Sun J, Qian P, Kang Y, Dai HB, Wang FZ, Wang HY, Zhou H, Gao Q, Zhou YB
Neuropeptides 2021 Feb;85:102109
Neuropeptides 2021 Feb;85:102109
Silenced microRNA-222 suppresses inflammatory response in gestational diabetes mellitus mice by promoting CXCR4.
Zhang H, Luan S, Xiao X, Lin L, Zhao X, Liu X
Life sciences 2021 Feb 1;266:118850
Life sciences 2021 Feb 1;266:118850
Long-term ketamine administration induces bladder damage and upregulates autophagy-associated proteins in bladder smooth muscle tissue.
Li Y, Dong Z, Wen G, Ren X, Ren W, Yan L, Wang X, Yu H, Wu X, Xia X, Lu Y, Wu X
Environmental toxicology 2021 Dec;36(12):2521-2529
Environmental toxicology 2021 Dec;36(12):2521-2529
Chicoric acid attenuates hyperglycemia-induced endothelial dysfunction through AMPK-dependent inhibition of oxidative/nitrative stresses.
Ma X, Zhang J, Wu Z, Wang X
Journal of receptor and signal transduction research 2021 Aug;41(4):378-392
Journal of receptor and signal transduction research 2021 Aug;41(4):378-392
Active components from Lagotis brachystachya maintain uric acid homeostasis by inhibiting renal TLR4-NLRP3 signaling in hyperuricemic mice.
Zhu JX, Yang HY, Hu WQ, Cheng J, Liu Y, Yi LT, Cheng HY
Inflammopharmacology 2021 Aug;29(4):1187-1200
Inflammopharmacology 2021 Aug;29(4):1187-1200
Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.
Ma L, Li C, Lian S, Xu B, Lv H, Liu Y, Lu J, Ji H, Li S, Guo J, Yang H
Journal of cellular and molecular medicine 2021 Aug;25(16):8015-8027
Journal of cellular and molecular medicine 2021 Aug;25(16):8015-8027
Pik3c3 deficiency in myeloid cells imparts partial resistance to experimental autoimmune encephalomyelitis associated with reduced IL-1β production.
Yang G, Song W, Xu J, Postoak JL, Cheng F, Martinez J, Zhang J, Wu L, Van Kaer L
Cellular & molecular immunology 2021 Aug;18(8):2024-2039
Cellular & molecular immunology 2021 Aug;18(8):2024-2039
Isoorientin Attenuated the Pyroptotic Hepatocyte Damage Induced by Benzo[a]pyrene via ROS/NF-κB/NLRP3/Caspase-1 Signaling Pathway.
Li H, Yuan L, Li X, Luo Y, Zhang Z, Li J
Antioxidants (Basel, Switzerland) 2021 Aug 11;10(8)
Antioxidants (Basel, Switzerland) 2021 Aug 11;10(8)
PCSK9 mediates the oxidative low‑density lipoprotein‑induced pyroptosis of vascular endothelial cells via the UQCRC1/ROS pathway.
Zeng J, Tao J, Xi L, Wang Z, Liu L
International journal of molecular medicine 2021 Apr;47(4)
International journal of molecular medicine 2021 Apr;47(4)
Aspergillus fumigatus-Stimulated Human Corneal Epithelial Cells Induce Pyroptosis of THP-1 Macrophages by Secreting TSLP.
Ji Q, Wang L, Liu J, Wu Y, Lv H, Wen Y, Shi L, Qu B, Szentmáry N
Inflammation 2021 Apr;44(2):682-692
Inflammation 2021 Apr;44(2):682-692
Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy.
Luo L, Jian X, Sun H, Qin J, Wang Y, Zhang J, Shen Z, Yang D, Li C, Zhao P, Liu M, Tian Z, Zhou Y
Stem cells (Dayton, Ohio) 2021 Apr;39(4):467-481
Stem cells (Dayton, Ohio) 2021 Apr;39(4):467-481
Loss of Arf Guanine Nucleotide Exchange Factor GBF1 Activity Disturbs Organelle Dynamics in Mouse Oocytes.
Zou YJ, Shan MM, Pan ZN, Pan MH, Li XH, Sun SC
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 2021 Apr;27(2):400-408
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 2021 Apr;27(2):400-408
CART mitigates oxidative stress and DNA damage in memory deficits of APP/PS1 mice via upregulating β‑amyloid metabolism‑associated enzymes.
Jiang H, Niu F, Zheng Y, Xu Y
Molecular medicine reports 2021 Apr;23(4)
Molecular medicine reports 2021 Apr;23(4)
Curcumin inhibits the growth of liver cancer by impairing myeloid-derived suppressor cells in murine tumor tissues.
Tian S, Liao L, Zhou Q, Huang X, Zheng P, Guo Y, Deng T, Tian X
Oncology letters 2021 Apr;21(4):286
Oncology letters 2021 Apr;21(4):286
Metformin effectively treats Tsc1 deletion-caused kidney pathology by upregulating AMPK phosphorylation.
Fang Y, Li F, Qi C, Mao X, Wang F, Zhao Z, Chen JK, Zhang Z, Wu H
Cell death discovery 2020;6:52
Cell death discovery 2020;6:52
Interleukin-1β-Induced Senescence Promotes Osteoblastic Transition of Vascular Smooth Muscle Cells.
Han L, Zhang Y, Zhang M, Guo L, Wang J, Zeng F, Xu D, Yin Z, Xu Y, Wang D, Zhou H
Kidney & blood pressure research 2020;45(2):314-330
Kidney & blood pressure research 2020;45(2):314-330
Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells.
Zheng P, Tian X, Zhang W, Yang Z, Zhou J, Zheng J, Cui H, Tang T, Luo J, Wang Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7210627
Evidence-based complementary and alternative medicine : eCAM 2020;2020:7210627
Protective Effects of Cinnamaldehyde against Mesenteric Ischemia-Reperfusion-Induced Lung and Liver Injuries in Rats.
Almoiliqy M, Wen J, Qaed E, Sun Y, Lian M, Mousa H, Al-Azab M, Zaky MY, Chen D, Wang L, Al-Sharabi A, Liu Z, Sun P, Lin Y
Oxidative medicine and cellular longevity 2020;2020:4196548
Oxidative medicine and cellular longevity 2020;2020:4196548
La2O3 Nanoparticles Induce Reproductive Toxicity Mediated by the Nrf-2/ARE Signaling Pathway in Kunming Mice.
Yuan L, Li Q, Bai D, Shang X, Hu F, Chen Z, An T, Chen Y, Zhang X
International journal of nanomedicine 2020;15:3415-3431
International journal of nanomedicine 2020;15:3415-3431
Blocking the LncRNA MALAT1/miR-224-5p/NLRP3 Axis Inhibits the Hippocampal Inflammatory Response in T2DM With OSA.
Du P, Wang J, Han Y, Feng J
Frontiers in cellular neuroscience 2020;14:97
Frontiers in cellular neuroscience 2020;14:97
Detection of proteins associated with the pyroptosis signaling pathway in breast cancer tissues and their significance.
Wu X, Mao X, Huang Y, Zhu Q, Guan J, Wu L
International journal of clinical and experimental pathology 2020;13(6):1408-1414
International journal of clinical and experimental pathology 2020;13(6):1408-1414
17-Allylamino-Demethoxygeldanamycin Ameliorate Microthrombosis Via HSP90/RIP3/NLRP3 Pathway After Subarachnoid Hemorrhage in Rats.
Zuo Y, He T, Liao P, Zhuang K, Yan X, Liu F
Acta neurochirurgica. Supplement 2020;127:69-75
Acta neurochirurgica. Supplement 2020;127:69-75
Pharmacological Inhibition of HDAC6 Attenuates NLRP3 Inflammatory Response and Protects Dopaminergic Neurons in Experimental Models of Parkinson's Disease.
Yan S, Wei X, Jian W, Qin Y, Liu J, Zhu S, Jiang F, Lou H, Zhang B
Frontiers in aging neuroscience 2020;12:78
Frontiers in aging neuroscience 2020;12:78
Manganese Exposure Aggravates β-Amyloid Pathology by Microglial Activation.
Lin G, Li X, Cheng X, Zhao N, Zheng W
Frontiers in aging neuroscience 2020;12:556008
Frontiers in aging neuroscience 2020;12:556008
Effect of C-phycocyanin on HDAC3 and miRNA-335 in Alzheimer's disease.
Li Z, Gan L, Yan S, Yan Y, Huang W
Translational neuroscience 2020;11(1):161-172
Translational neuroscience 2020;11(1):161-172
Ablation of GSDMD Improves Outcome of Ischemic Stroke Through Blocking Canonical and Non-canonical Inflammasomes Dependent Pyroptosis in Microglia.
Wang K, Sun Z, Ru J, Wang S, Huang L, Ruan L, Lin X, Jin K, Zhuge Q, Yang S
Frontiers in neurology 2020;11:577927
Frontiers in neurology 2020;11:577927
Role of Endoplasmic Reticulum Stress in Otitis Media.
Zhao H, Wang Y, Li B, Zheng T, Liu X, Hu BH, Che J, Zhao T, Chen J, Hatzoglou M, Zhang X, Fan Z, Zheng Q
Frontiers in genetics 2020;11:495
Frontiers in genetics 2020;11:495
Critical Role of AdipoR1 in Regulating Th17 Cell Differentiation Through Modulation of HIF-1α-Dependent Glycolysis.
Zhang Q, Wang L, Jiang J, Lin S, Luo A, Zhao P, Tan W, Zhang M
Frontiers in immunology 2020;11:2040
Frontiers in immunology 2020;11:2040
Porphyromonas gingivalis-Induced NLRP3 Inflammasome Activation and Its Downstream Interleukin-1β Release Depend on Caspase-4.
Ding PH, Yang MX, Wang NN, Jin LJ, Dong Y, Cai X, Chen LL
Frontiers in microbiology 2020;11:1881
Frontiers in microbiology 2020;11:1881
Selenomethionine Suppressed TLR4/NF-κB Pathway by Activating Selenoprotein S to Alleviate ESBL Escherichia coli-Induced Inflammation in Bovine Mammary Epithelial Cells and Macrophages.
Zhuang C, Liu G, Barkema HW, Zhou M, Xu S, Ur Rahman S, Liu Y, Kastelic JP, Gao J, Han B
Frontiers in microbiology 2020;11:1461
Frontiers in microbiology 2020;11:1461
Caffeic Acid Phenethyl Ester Prevents Colitis-Associated Cancer by Inhibiting NLRP3 Inflammasome.
Dai G, Jiang Z, Sun B, Liu C, Meng Q, Ding K, Jing W, Ju W
Frontiers in oncology 2020;10:721
Frontiers in oncology 2020;10:721
Fucoidan inhibits tooth movement by promoting restorative macrophage polarization through the STAT3 pathway.
Zhang S, Zhang H, Jin Z, Wang S, Wang Y, Zhu L, Sun W, Yan B
Journal of cellular physiology 2020 Sep;235(9):5938-5950
Journal of cellular physiology 2020 Sep;235(9):5938-5950
Peptidome analysis of umbilical cord mesenchymal stem cell (hUC-MSC) conditioned medium from preterm and term infants.
Wang Y, Zhang L, Wu Y, Zhu R, Wang Y, Cao Y, Long W, Ji C, Wang H, You L
Stem cell research & therapy 2020 Sep 23;11(1):414
Stem cell research & therapy 2020 Sep 23;11(1):414
Monotropein alleviates secondary liver injury in chronic colitis by regulating TLR4/NF-κB signaling and NLRP3 inflammasome.
Chen Y, Lu Y, Pei C, Liang J, Ding P, Chen S, Hou SZ
European journal of pharmacology 2020 Sep 15;883:173358
European journal of pharmacology 2020 Sep 15;883:173358
Hypertonic saline mediates the NLRP3/IL-1β signaling axis in microglia to alleviate ischemic blood-brain barrier permeability by downregulating astrocyte-derived VEGF in rats.
Wang QS, Ding HG, Chen SL, Liu XQ, Deng YY, Jiang WQ, Li Y, Huang LQ, Han YL, Wen MY, Wang MQ, Zeng HK
CNS neuroscience & therapeutics 2020 Oct;26(10):1045-1057
CNS neuroscience & therapeutics 2020 Oct;26(10):1045-1057
Trimethylamine N-oxide promotes apoE-/- mice atherosclerosis by inducing vascular endothelial cell pyroptosis via the SDHB/ROS pathway.
Wu P, Chen J, Chen J, Tao J, Wu S, Xu G, Wang Z, Wei D, Yin W
Journal of cellular physiology 2020 Oct;235(10):6582-6591
Journal of cellular physiology 2020 Oct;235(10):6582-6591
Protective effect of astaxanthin against La2O3 nanoparticles induced neurotoxicity by activating PI3K/AKT/Nrf-2 signaling in mice.
Yuan L, Qu Y, Li Q, An T, Chen Z, Chen Y, Deng X, Bai D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Oct;144:111582
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2020 Oct;144:111582
Transcriptomic Analysis of Age-Associated Periventricular Lesions Reveals Dysregulation of the Immune Response.
Fadul MM, Heath PR, Cooper-Knock J, Kurz JM, Al-Azzawi HA, Ali Z, Smith T, Matthews FE, Brayne C, Wharton SB, Simpson JE
International journal of molecular sciences 2020 Oct 25;21(21)
International journal of molecular sciences 2020 Oct 25;21(21)
LncRNA GAS5 inhibits NLRP3 inflammasome activation-mediated pyroptosis in diabetic cardiomyopathy by targeting miR-34b-3p/AHR.
Xu Y, Fang H, Xu Q, Xu C, Yang L, Huang C
Cell cycle (Georgetown, Tex.) 2020 Nov;19(22):3054-3065
Cell cycle (Georgetown, Tex.) 2020 Nov;19(22):3054-3065
Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models.
Liu YC, Wang HL, Huang YZ, Weng YH, Chen RS, Tsai WC, Yeh TH, Lu CS, Chen YL, Lin YW, Chen YJ, Hsu CC, Chiu CH, Chiu CC
Biochemical pharmacology 2020 May;175:113919
Biochemical pharmacology 2020 May;175:113919
The Differential Expression of Cytokines and Growth Factors After SMILE Compared With FS-LASIK in Rabbits.
Liu L, Cheng W, Wu D, Chen L, Yu S, Zuo T, Zhang L, Yang K, Li H, Zhang H, Wei P, Ng ALK, Cheng GP, Woo VC, Yin J, Chiu K, Wang Y
Investigative ophthalmology & visual science 2020 May 11;61(5):55
Investigative ophthalmology & visual science 2020 May 11;61(5):55
LINC01116 promotes tumor proliferation and neutrophil recruitment via DDX5-mediated regulation of IL-1β in glioma cell.
Wang T, Cao L, Dong X, Wu F, De W, Huang L, Wan Q
Cell death & disease 2020 May 1;11(5):302
Cell death & disease 2020 May 1;11(5):302
Aging alters Hv1-mediated microglial polarization and enhances neuroinflammation after peripheral surgery.
Zhang ZJ, Zheng XX, Zhang XY, Zhang Y, Huang BY, Luo T
CNS neuroscience & therapeutics 2020 Mar;26(3):374-384
CNS neuroscience & therapeutics 2020 Mar;26(3):374-384
ACPAs promote IL-1β production in rheumatoid arthritis by activating the NLRP3 inflammasome.
Dong X, Zheng Z, Lin P, Fu X, Li F, Jiang J, Zhu P
Cellular & molecular immunology 2020 Mar;17(3):261-271
Cellular & molecular immunology 2020 Mar;17(3):261-271
The Biomarker TCONS_00016233 Drives Septic AKI by Targeting the miR-22-3p/AIFM1 Signaling Axis.
Zhang P, Yi L, Qu S, Dai J, Li X, Liu B, Li H, Ai K, Zheng P, Qiu S, Li Y, Wang Y, Xiang X, Chai X, Dong Z, Zhang D
Molecular therapy. Nucleic acids 2020 Mar 6;19:1027-1042
Molecular therapy. Nucleic acids 2020 Mar 6;19:1027-1042
Microglia polarization of hippocampus is involved in the mechanism of Apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats.
Zhou S, Chen S, Xie W, Guo X, Zhao J
Neuropeptides 2020 Jun;81:102006
Neuropeptides 2020 Jun;81:102006
Obesity induces preadipocyte CD36 expression promoting inflammation via the disruption of lysosomal calcium homeostasis and lysosome function.
Luo X, Li Y, Yang P, Chen Y, Wei L, Yu T, Xia J, Ruan XZ, Zhao L, Chen Y
EBioMedicine 2020 Jun;56:102797
EBioMedicine 2020 Jun;56:102797
TNF-α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury.
Wang Y, Zhang H, Chen Q, Jiao F, Shi C, Pei M, Lv J, Zhang H, Wang L, Gong Z
Cell proliferation 2020 Jun;53(6):e12829
Cell proliferation 2020 Jun;53(6):e12829
Anti-human serum albumin autoantibody may be involved in the pathogenesis of autoimmune bullous skin diseases.
Qian H, Cao Y, Sun J, Zu J, Ma L, Zhou H, Tang X, Li Y, Yu H, Zhang M, Bai Y, Xu C, Ishii N, Hashimoto T, Li X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):8574-8595
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):8574-8595
Corneal epithelial injury-induced norepinephrine promotes Pseudomonas aeruginosa keratitis.
Ma X, Wang Q, Song F, Li Y, Li J, Dou S, Xie L, Zhou Q
Experimental eye research 2020 Jun;195:108048
Experimental eye research 2020 Jun;195:108048
CX3CR1-microglia mediates neuroinflammation and blood pressure regulation in the nucleus tractus solitarii of fructose-induced hypertensive rats.
Ho CY, Lin YT, Chen HH, Ho WY, Sun GC, Hsiao M, Lu PJ, Cheng PW, Tseng CJ
Journal of neuroinflammation 2020 Jun 12;17(1):185
Journal of neuroinflammation 2020 Jun 12;17(1):185
Albendazole-Schisandrin B Co-Therapy on Angiostrongylus cantonensis-Induced Meningoencephalitis in Mice.
Lam HYP, Liang TR, Jiang SJ, Peng SY
Biomolecules 2020 Jul 5;10(7)
Biomolecules 2020 Jul 5;10(7)
NLRP3 inflammasome-mediated microglial pyroptosis is critically involved in the development of post-cardiac arrest brain injury.
Chang Y, Zhu J, Wang D, Li H, He Y, Liu K, Wang X, Peng Y, Pan S, Huang K
Journal of neuroinflammation 2020 Jul 23;17(1):219
Journal of neuroinflammation 2020 Jul 23;17(1):219
Mechanism investigation on Bisphenol S-induced oxidative stress and inflammation in murine RAW264.7 cells: The role of NLRP3 inflammasome, TLR4, Nrf2 and MAPK.
Xie C, Ge M, Jin J, Xu H, Mao L, Geng S, Wu J, Zhu J, Li X, Zhong C
Journal of hazardous materials 2020 Jul 15;394:122549
Journal of hazardous materials 2020 Jul 15;394:122549
Dendrobium Alkaloids Promote Neural Function After Cerebral Ischemia-Reperfusion Injury Through Inhibiting Pyroptosis Induced Neuronal Death in both In Vivo and In Vitro Models.
Liu D, Dong Z, Xiang F, Liu H, Wang Y, Wang Q, Rao J
Neurochemical research 2020 Feb;45(2):437-454
Neurochemical research 2020 Feb;45(2):437-454
α-synuclein promotes progression of Parkinson's disease by upregulating autophagy signaling pathway to activate NLRP3 inflammasome.
Wang X, Chi J, Huang D, Ding L, Zhao X, Jiang L, Yu Y, Gao F
Experimental and therapeutic medicine 2020 Feb;19(2):931-938
Experimental and therapeutic medicine 2020 Feb;19(2):931-938
NR1D1 modulates synovial inflammation and bone destruction in rheumatoid arthritis.
Liu H, Zhu Y, Gao Y, Qi D, Zhao L, Zhao L, Liu C, Tao T, Zhou C, Sun X, Guo F, Xiao J
Cell death & disease 2020 Feb 18;11(2):129
Cell death & disease 2020 Feb 18;11(2):129
Eicosapentaenoic acid prevents inflammation induced by acute cerebral infarction through inhibition of NLRP3 inflammasome activation.
Mo Z, Tang C, Li H, Lei J, Zhu L, Kou L, Li H, Luo S, Li C, Chen W, Zhang L
Life sciences 2020 Feb 1;242:117133
Life sciences 2020 Feb 1;242:117133
Maresin 1 mitigates concanavalin A-induced acute liver injury in mice by inhibiting ROS-mediated activation of NF-κB signaling.
Zhang P, Yin Y, Wang T, Li W, Li C, Zeng X, Yang W, Zhang R, Tang Y, Shi L, Li R, Tao K
Free radical biology & medicine 2020 Feb 1;147:23-36
Free radical biology & medicine 2020 Feb 1;147:23-36
GABA-mediated activated microglia induce neuroinflammation in the hippocampus of mice following cold exposure through the NLRP3 inflammasome and NF-κB signaling pathways.
Lang L, Xu B, Yuan J, Li S, Lian S, Chen Y, Guo J, Yang H
International immunopharmacology 2020 Dec;89(Pt B):106908
International immunopharmacology 2020 Dec;89(Pt B):106908
Infrapatellar fat pads participate in the development of knee osteoarthritis in obese patients via the activation of the NF‑κB signaling pathway.
Duan L, Ma Y, Wang Y, Liu J, Tan Z, Wu Q, Wu Y, Yu X
International journal of molecular medicine 2020 Dec;46(6):2260-2270
International journal of molecular medicine 2020 Dec;46(6):2260-2270
A research of STEAP1 regulated gastric cancer cell proliferation, migration and invasion in vitro and in vivos.
Zhang Z, Hou WB, Zhang C, Tan YE, Zhang DD, An W, Pan SW, Wu WD, Chen QC, Xu HM
Journal of cellular and molecular medicine 2020 Dec;24(24):14217-14230
Journal of cellular and molecular medicine 2020 Dec;24(24):14217-14230
Chronic ethanol exposure induces neuroinflammation in H4 cells through TLR3 / NF-κB pathway and anxiety-like behavior in male C57BL/6 mice.
Wang X, Yu H, Wang C, Liu Y, You J, Wang P, Xu G, Shen H, Yao H, Lan X, Zhao R, Wu X, Zhang G
Toxicology 2020 Dec 15;446:152625
Toxicology 2020 Dec 15;446:152625
Akkermansia muciniphila promotes type H vessel formation and bone fracture healing by reducing gut permeability and inflammation.
Liu JH, Yue T, Luo ZW, Cao J, Yan ZQ, Jin L, Wan TF, Shuai CJ, Wang ZG, Zhou Y, Xu R, Xie H
Disease models & mechanisms 2020 Dec 1;13(11)
Disease models & mechanisms 2020 Dec 1;13(11)
Angiostrongylus cantonensis activates inflammasomes in meningoencephalitic BALB/c mice.
Lam HYP, Chen TT, Chen CC, Yang TH, Cheng PC, Peng SY
Parasitology international 2020 Aug;77:102119
Parasitology international 2020 Aug;77:102119
Salvianic acid A alleviates chronic alcoholic liver disease by inhibiting HMGB1 translocation via down-regulating BRD4.
Lan Y, Yan R, Shan W, Chu J, Sun R, Wang R, Zhao Y, Wang Z, Zhang N, Yao J
Journal of cellular and molecular medicine 2020 Aug;24(15):8518-8531
Journal of cellular and molecular medicine 2020 Aug;24(15):8518-8531
FGF21 mitigates atherosclerosis via inhibition of NLRP3 inflammasome-mediated vascular endothelial cells pyroptosis.
Zeng Z, Zheng Q, Chen J, Tan X, Li Q, Ding L, Zhang R, Lin X
Experimental cell research 2020 Aug 15;393(2):112108
Experimental cell research 2020 Aug 15;393(2):112108
Salidroside Decreases Atherosclerosis Plaque Formation via Inhibiting Endothelial Cell Pyroptosis.
Xing SS, Yang J, Li WJ, Li J, Chen L, Yang YT, Lei X, Li J, Wang K, Liu X
Inflammation 2020 Apr;43(2):433-440
Inflammation 2020 Apr;43(2):433-440
Inhibition of the ox-LDL-Induced Pyroptosis by FGF21 of Human Umbilical Vein Endothelial Cells Through the TET2-UQCRC1-ROS Pathway.
Chen JJ, Tao J, Zhang XL, Xia LZ, Zeng JF, Zhang H, Wei DH, Lv YC, Li GH, Wang Z
DNA and cell biology 2020 Apr;39(4):661-670
DNA and cell biology 2020 Apr;39(4):661-670
COMP in the Infrapatellar Fat Pad-Results of a Prospective Histological, Immunohistological, and Biochemical Case-Control Study.
Grevenstein D, Heilig J, Dargel J, Oppermann J, Eysel P, Brochhausen C, Niehoff A
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2020 Apr;38(4):747-758
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2020 Apr;38(4):747-758
High- and low-virulent bovine Pasteurella multocida induced differential NLRP3 inflammasome activation and subsequent IL-1β secretion.
Fang R, Lei G, Jiang J, Du H, Liu Y, Lei Z, Ye C, Li N, Peng Y
Veterinary microbiology 2020 Apr;243:108646
Veterinary microbiology 2020 Apr;243:108646
p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species.
Zhao Y, Wang Z, Feng D, Zhao H, Lin M, Hu Y, Zhang N, Lv L, Gao Z, Zhai X, Tian X, Yao J
Theranostics 2019;9(5):1510-1522
Theranostics 2019;9(5):1510-1522
Antitumor Effects of Berberine on Gliomas via Inactivation of Caspase-1-Mediated IL-1β and IL-18 Release.
Tong L, Xie C, Wei Y, Qu Y, Liang H, Zhang Y, Xu T, Qian X, Qiu H, Deng H
Frontiers in oncology 2019;9:364
Frontiers in oncology 2019;9:364
NLRP3 Inflammasome Is Involved in Calcium-Sensing Receptor-Induced Aortic Remodeling in SHRs.
Zhang X, Hong S, Qi S, Liu W, Zhang X, Shi Z, Chen W, Zhao M, Yin X
Mediators of inflammation 2019;2019:6847087
Mediators of inflammation 2019;2019:6847087
Purple Sweet Potato Color Attenuates Kidney Damage by Blocking VEGFR2/ROS/NLRP3 Signaling in High-Fat Diet-Treated Mice.
Zheng GH, Shan Q, Mu JJ, Wang YJ, Zhang ZF, Fan SH, Hu B, Li MQ, Xie J, Chen P, Wu DM, Lu J, Zheng YL
Oxidative medicine and cellular longevity 2019;2019:5189819
Oxidative medicine and cellular longevity 2019;2019:5189819
Hydrogen Inhalation Attenuates Oxidative Stress Related Endothelial Cells Injury After Subarachnoid Hemorrhage in Rats.
Zhuang K, Zuo YC, Sherchan P, Wang JK, Yan XX, Liu F
Frontiers in neuroscience 2019;13:1441
Frontiers in neuroscience 2019;13:1441
Sorghum Phenolics Inhibits Inflammasomes in Lipopolysaccharide (LPS)-Primed and Adenosine Triphosphate (ATP)-Activated Macrophages.
Dia VP, Bradwell J, Pangloli P
Plant foods for human nutrition (Dordrecht, Netherlands) 2019 Sep;74(3):307-315
Plant foods for human nutrition (Dordrecht, Netherlands) 2019 Sep;74(3):307-315
Vaccaria n-Butanol Extract Lower the Production of Proinflammatory Cytokines and the Infection Risk of T. spiralis In Vivo.
Xu F, Hou B, Zhu X, Liu Y, Shi X, Li S, Li Z, Cai W, Zhou Y, Qiu L
Acta parasitologica 2019 Sep;64(3):520-527
Acta parasitologica 2019 Sep;64(3):520-527
Hydrogen inhalation protects hypoxic-ischemic brain damage by attenuating inflammation and apoptosis in neonatal rats.
Wu G, Chen Z, Wang P, Zhao M, Fujino M, Zhang C, Zhou W, Hirano SI, Li XK, Zhao L
Experimental biology and medicine (Maywood, N.J.) 2019 Sep;244(12):1017-1027
Experimental biology and medicine (Maywood, N.J.) 2019 Sep;244(12):1017-1027
TAK242 suppresses the TLR4 signaling pathway and ameliorates DCD liver IRI in rats.
Zhong X, Xiao Q, Liu Z, Wang W, Lai CH, Yang W, Yue P, Ye Q, Xiao J
Molecular medicine reports 2019 Sep;20(3):2101-2110
Molecular medicine reports 2019 Sep;20(3):2101-2110
MiR-143-3p directly targets GLUT9 to reduce uric acid reabsorption and inflammatory response of renal tubular epithelial cells.
Zhou Z, Dong Y, Zhou H, Liu J, Zhao W
Biochemical and biophysical research communications 2019 Sep 24;517(3):413-420
Biochemical and biophysical research communications 2019 Sep 24;517(3):413-420
Upregulation of miR-93 and inhibition of LIMK1 improve ventricular remodeling and alleviate cardiac dysfunction in rats with chronic heart failure by inhibiting RhoA/ROCK signaling pathway activation.
Su Q, Zhang P, Yu D, Wu Z, Li D, Shen F, Liao P, Yin G
Aging 2019 Sep 20;11(18):7570-7586
Aging 2019 Sep 20;11(18):7570-7586
Migratory Neural Crest Cells Phagocytose Dead Cells in the Developing Nervous System.
Zhu Y, Crowley SC, Latimer AJ, Lewis GM, Nash R, Kucenas S
Cell 2019 Sep 19;179(1):74-89.e10
Cell 2019 Sep 19;179(1):74-89.e10
Pyroptosis engagement and bladder urothelial cell-derived exosomes recruit mast cells and induce barrier dysfunction of bladder urothelium after uropathogenic E. coli infection.
Wu Z, Li Y, Liu Q, Liu Y, Chen L, Zhao H, Guo H, Zhu K, Zhou N, Chai TC, Shi B
American journal of physiology. Cell physiology 2019 Sep 1;317(3):C544-C555
American journal of physiology. Cell physiology 2019 Sep 1;317(3):C544-C555
LncRNA HIF1A-AS1 contributes to ventricular remodeling after myocardial ischemia/reperfusion injury by adsorption of microRNA-204 to regulating SOCS2 expression.
Xue X, Luo L
Cell cycle (Georgetown, Tex.) 2019 Oct;18(19):2465-2480
Cell cycle (Georgetown, Tex.) 2019 Oct;18(19):2465-2480
Curcumin attenuates potassium oxonate-induced hyperuricemia and kidney inflammation in mice.
Chen Y, Li C, Duan S, Yuan X, Liang J, Hou S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109195
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109195
IMM-H007, a novel small molecule inhibitor for atherosclerosis, represses endothelium inflammation by regulating the activity of NF-κB and JNK/AP1 signaling.
Yu J, Ming H, Li HY, Yu B, Chu M, Zhu H, Zhu X
Toxicology and applied pharmacology 2019 Oct 15;381:114732
Toxicology and applied pharmacology 2019 Oct 15;381:114732
SETD7 mediates spinal microgliosis and neuropathic pain in a rat model of peripheral nerve injury.
Shen Y, Ding Z, Ma S, Ding Z, Zhang Y, Zou Y, Xu F, Yang X, Schäfer MKE, Guo Q, Huang C
Brain, behavior, and immunity 2019 Nov;82:382-395
Brain, behavior, and immunity 2019 Nov;82:382-395
Akt inhibitor deguelin aggravates inflammation and fibrosis in myocarditis.
Li S, Wang Y, Zhao C, Zhang M, Wang W, Yu X, Huang J, Wang Z, Zhu B, Yin C, Cai H
Iranian journal of basic medical sciences 2019 Nov;22(11):1275-1282
Iranian journal of basic medical sciences 2019 Nov;22(11):1275-1282
Iguratimod (T-614) attenuates severe acute pancreatitis by inhibiting the NLRP3 inflammasome and NF-κB pathway.
Hou C, Zhu X, Shi C, Peng Y, Huang D, Li Q, Miao Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Nov;119:109455
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Nov;119:109455
Ameliorative effects of echinacoside against spinal cord injury via inhibiting NLRP3 inflammasome signaling pathway.
Gao S, Xu T, Guo H, Deng Q, Xun C, Liang W, Sheng W
Life sciences 2019 Nov 15;237:116978
Life sciences 2019 Nov 15;237:116978
Gender Difference in Damage-Mediated Signaling Contributes to Pulmonary Arterial Hypertension.
Rafikov R, Nair V, Sinari S, Babu H, Sullivan JC, Yuan JX, Desai AA, Rafikova O
Antioxidants & redox signaling 2019 Nov 1;31(13):917-932
Antioxidants & redox signaling 2019 Nov 1;31(13):917-932
OxLDL induces vascular endothelial cell pyroptosis through miR-125a-5p/TET2 pathway.
Zhaolin Z, Jiaojiao C, Peng W, Yami L, Tingting Z, Jun T, Shiyuan W, Jinyan X, Dangheng W, Zhisheng J, Zuo W
Journal of cellular physiology 2019 May;234(5):7475-7491
Journal of cellular physiology 2019 May;234(5):7475-7491
Purple sweet potato color attenuated NLRP3 inflammasome by inducing autophagy to delay endothelial senescence.
Sun C, Diao Q, Lu J, Zhang Z, Wu D, Wang X, Xie J, Zheng G, Shan Q, Fan S, Hu B, Zheng Y
Journal of cellular physiology 2019 May;234(5):5926-5939
Journal of cellular physiology 2019 May;234(5):5926-5939
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
Jia YN, Peng YL, Zhao YP, Cheng XF, Zhou Y, Chai CL, Zeng LS, Pan MH, Xu L
Journal of agricultural and food chemistry 2019 May 15;67(19):5521-5529
Journal of agricultural and food chemistry 2019 May 15;67(19):5521-5529
Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice.
He Y, Xia Z, Yu D, Wang J, Jin L, Huang D, Ye X, Li X, Zhang B
International immunopharmacology 2019 Mar;68:171-178
International immunopharmacology 2019 Mar;68:171-178
Tougu Xiaotong capsule exerts a therapeutic effect on knee osteoarthritis by regulating subchondral bone remodeling.
Wu G, Zhang J, Chen W, Chen S, Huang Y, Lin R, Huang M, Li Z, Zheng L, Li X
Molecular medicine reports 2019 Mar;19(3):1858-1866
Molecular medicine reports 2019 Mar;19(3):1858-1866
Sweroside Alleviated LPS-Induced Inflammation via SIRT1 Mediating NF-κB and FOXO1 Signaling Pathways in RAW264.7 Cells.
Wang R, Dong Z, Lan X, Liao Z, Chen M
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
Molecules (Basel, Switzerland) 2019 Mar 1;24(5)
Caspase-11 promotes renal fibrosis by stimulating IL-1β maturation via activating caspase-1.
Miao NJ, Xie HY, Xu D, Yin JY, Wang YZ, Wang B, Yin F, Zhou ZL, Cheng Q, Chen PP, Zhou L, Xue H, Zhang W, Wang XX, Liu J, Lu LM
Acta pharmacologica Sinica 2019 Jun;40(6):790-800
Acta pharmacologica Sinica 2019 Jun;40(6):790-800
Clock mutant promotes osteoarthritis by inhibiting the acetylation of NFκB.
Yuan G, Xu L, Cai T, Hua B, Sun N, Yan Z, Lu C, Qian R
Osteoarthritis and cartilage 2019 Jun;27(6):922-931
Osteoarthritis and cartilage 2019 Jun;27(6):922-931
STING-IRF3 contributes to lipopolysaccharide-induced cardiac dysfunction, inflammation, apoptosis and pyroptosis by activating NLRP3.
Li N, Zhou H, Wu H, Wu Q, Duan M, Deng W, Tang Q
Redox biology 2019 Jun;24:101215
Redox biology 2019 Jun;24:101215
An NLRP3 inflammasome-triggered cytokine storm contributes to Streptococcal toxic shock-like syndrome (STSLS).
Lin L, Xu L, Lv W, Han L, Xiang Y, Fu L, Jin M, Zhou R, Chen H, Zhang A
PLoS pathogens 2019 Jun;15(6):e1007795
PLoS pathogens 2019 Jun;15(6):e1007795
Chitosan Hydrogel Delivery System Containing Herbal Compound Functions as a Potential Antineuroinflammatory Agent.
Zhou J, Zheng J, Zhang Y, Zheng P, Tang T, Luo JK, Cui HJ, Song RR, Wang Y
ACS omega 2019 Jun 30;4(6):10185-10191
ACS omega 2019 Jun 30;4(6):10185-10191
NLRP3 inflammasome activates interleukin-23/interleukin-17 axis during ischaemia-reperfusion injury in cerebral ischaemia in mice.
Wang H, Zhong D, Chen H, Jin J, Liu Q, Li G
Life sciences 2019 Jun 15;227:101-113
Life sciences 2019 Jun 15;227:101-113
Helicobacter pylori-induced YAP1 nuclear translocation promotes gastric carcinogenesis by enhancing IL-1β expression.
Wu Y, Shen L, Liang X, Li S, Ma L, Zheng L, Li T, Yu H, Chan H, Chen C, Yu J, Jia J
Cancer medicine 2019 Jul;8(8):3965-3980
Cancer medicine 2019 Jul;8(8):3965-3980
Pioglitazone decreased renal calcium oxalate crystal formation by suppressing M1 macrophage polarization via the PPAR-γ-miR-23 axis.
Chen Z, Yuan P, Sun X, Tang K, Liu H, Han S, Ye T, Liu X, Yang X, Zeng J, Yan L, Xing J, Xiao K, Ye Z, Xu H
American journal of physiology. Renal physiology 2019 Jul 1;317(1):F137-F151
American journal of physiology. Renal physiology 2019 Jul 1;317(1):F137-F151
The synergistic effect of NOD2 and TLR4 on the activation of autophagy in human submandibular gland inflammation.
Li J, Li B, Cheng Y, Meng Q, Wei L, Li W, Zhang J, Huang S
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2019 Jan;48(1):87-95
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2019 Jan;48(1):87-95
OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice.
Yuan C, Guo X, Zhou Q, Du F, Jiang W, Zhou X, Liu P, Chi T, Ji X, Gao J, Chen C, Lang H, Xu J, Liu D, Yang Y, Qiu S, Tang X, Chen G, Zou L
Biochimica et biophysica acta. Molecular basis of disease 2019 Jan;1865(1):161-180
Biochimica et biophysica acta. Molecular basis of disease 2019 Jan;1865(1):161-180
Relationship between serum IL-1β and insomnia and liver depression in patients with perimenopausal non-organic sleep disorder.
Li H, Chen Y, Wu H, Huang J, Ma K, Zheng J, Lv S
Experimental and therapeutic medicine 2019 Jan;17(1):759-763
Experimental and therapeutic medicine 2019 Jan;17(1):759-763
LXRα promotes cell metastasis by regulating the NLRP3 inflammasome in renal cell carcinoma.
Wang K, Xu T, Ruan H, Xiao H, Liu J, Song Z, Cao Q, Bao L, Liu D, Wang C, Cheng G, Liang H, Chen Z, Yang H, Chen K, Zhang X
Cell death & disease 2019 Feb 15;10(3):159
Cell death & disease 2019 Feb 15;10(3):159
Juxtaposition of IL-1β and IFN-γ expression and apoptosis of keratinocytes in adult-onset Still's disease.
Rao S, Li Q, Wu H, Zhao M, Wang A, Zhang G, Li J, Lu L, Shi W, Lu Q
Expert review of clinical immunology 2019 Dec;15(12):1341-1350
Expert review of clinical immunology 2019 Dec;15(12):1341-1350
Differential immune responses of C57BL/6 mice to infection by Salmonella enterica serovar Typhimurium strain SL1344, CVCC541 and CMCC50115.
Wei S, Huang J, Liu Z, Wang M, Zhang B, Lian Z, Guo Y, Han H
Virulence 2019 Dec;10(1):248-259
Virulence 2019 Dec;10(1):248-259
Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway.
Wang Z, Liang M, Li H, Cai L, Yang L
International journal of molecular sciences 2019 Dec 6;20(24)
International journal of molecular sciences 2019 Dec 6;20(24)
Liraglutide ameliorates non-alcoholic steatohepatitis by inhibiting NLRP3 inflammasome and pyroptosis activation via mitophagy.
Yu X, Hao M, Liu Y, Ma X, Lin W, Xu Q, Zhou H, Shao N, Kuang H
European journal of pharmacology 2019 Dec 1;864:172715
European journal of pharmacology 2019 Dec 1;864:172715
Schwann cell transplantation exerts neuroprotective roles in rat model of spinal cord injury by combating inflammasome activation and improving motor recovery and remyelination.
Mousavi M, Hedayatpour A, Mortezaee K, Mohamadi Y, Abolhassani F, Hassanzadeh G
Metabolic brain disease 2019 Aug;34(4):1117-1130
Metabolic brain disease 2019 Aug;34(4):1117-1130
Bacteroides fragilis Strain ZY-312 Defense against Cronobacter sakazakii-Induced Necrotizing Enterocolitis In Vitro and in a Neonatal Rat Model.
Fan H, Chen Z, Lin R, Liu Y, Wu X, Puthiyakunnon S, Wang Y, Zhu B, Zhang Q, Bai Y, Zhi F
mSystems 2019 Aug 6;4(4)
mSystems 2019 Aug 6;4(4)
Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure.
Xu B, Lang LM, Li SZ, Guo JR, Wang JF, Yang HM, Lian S
Biomolecules 2019 Aug 30;9(9)
Biomolecules 2019 Aug 30;9(9)
Berberine inhibits NLRP3 Inflammasome pathway in human triple-negative breast cancer MDA-MB-231 cell.
Yao M, Fan X, Yuan B, Takagi N, Liu S, Han X, Ren J, Liu J
BMC complementary and alternative medicine 2019 Aug 14;19(1):216
BMC complementary and alternative medicine 2019 Aug 14;19(1):216
Gasdermin-d Played a Critical Role in the Cyclic Stretch-Induced Inflammatory Reaction in Human Periodontal Ligament Cells.
Zhuang J, Wang Y, Qu F, Wu Y, Zhao D, Xu C
Inflammation 2019 Apr;42(2):548-558
Inflammation 2019 Apr;42(2):548-558
Role of Thymoquinone in Cardiac Damage Caused by Sepsis from BALB/c Mice.
Liu H, Sun Y, Zhang Y, Yang G, Guo L, Zhao Y, Pei Z
Inflammation 2019 Apr;42(2):516-525
Inflammation 2019 Apr;42(2):516-525
NLRP3 inflammasome plays an important role in caspase-1 activation and IL-1β secretion in macrophages infected with Pasteurella multocida.
Fang R, Du H, Lei G, Liu Y, Feng S, Ye C, Li N, Peng Y
Veterinary microbiology 2019 Apr;231:207-213
Veterinary microbiology 2019 Apr;231:207-213
Protective effects of ginsenoside Rk3 against chronic alcohol-induced liver injury in mice through inhibition of inflammation, oxidative stress, and apoptosis.
Qu L, Zhu Y, Liu Y, Yang H, Zhu C, Ma P, Deng J, Fan D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Apr;126:277-284
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2019 Apr;126:277-284
Directed self-assembly of herbal small molecules into sustained release hydrogels for treating neural inflammation.
Zheng J, Fan R, Wu H, Yao H, Yan Y, Liu J, Ran L, Sun Z, Yi L, Dang L, Gan P, Zheng P, Yang T, Zhang Y, Tang T, Wang Y
Nature communications 2019 Apr 8;10(1):1604
Nature communications 2019 Apr 8;10(1):1604
The Anticonvulsant Effects of Baldrinal on Pilocarpine-Induced convulsion in Adult Male Mice.
Zhang X, Li X, Liu N, Zheng P, Ma L, Guo F, Sun T, Zhou R, Yu J
Molecules (Basel, Switzerland) 2019 Apr 24;24(8)
Molecules (Basel, Switzerland) 2019 Apr 24;24(8)
Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice.
Mao J, Yi M, Wang R, Huang Y, Chen M
Frontiers in pharmacology 2018;9:1469
Frontiers in pharmacology 2018;9:1469
Omentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines.
Rao SS, Hu Y, Xie PL, Cao J, Wang ZX, Liu JH, Yin H, Huang J, Tan YJ, Luo J, Luo MJ, Tang SY, Chen TH, Yuan LQ, Liao EY, Xu R, Liu ZZ, Chen CY, Xie H
Bone research 2018;6:9
Bone research 2018;6:9
Methane-Rich Saline Ameliorates Sepsis-Induced Acute Kidney Injury through Anti-Inflammation, Antioxidative, and Antiapoptosis Effects by Regulating Endoplasmic Reticulum Stress.
Jia Y, Li Z, Feng Y, Cui R, Dong Y, Zhang X, Xiang X, Qu K, Liu C, Zhang J
Oxidative medicine and cellular longevity 2018;2018:4756846
Oxidative medicine and cellular longevity 2018;2018:4756846
Expression and clinical significance of the NEK7-NLRP3 inflammasome signaling pathway in patients with systemic lupus erythematosus.
Ma ZZ, Sun HS, Lv JC, Guo L, Yang QR
Journal of inflammation (London, England) 2018;15:16
Journal of inflammation (London, England) 2018;15:16
Inhibition of Heat Shock Protein 90 by 17-AAG Reduces Inflammation via P2X7 Receptor/NLRP3 Inflammasome Pathway and Increases Neurogenesis After Subarachnoid Hemorrhage in Mice.
Zuo Y, Wang J, Liao F, Yan X, Li J, Huang L, Liu F
Frontiers in molecular neuroscience 2018;11:401
Frontiers in molecular neuroscience 2018;11:401
Combination Treatment of Icariin and L-DOPA Against 6-OHDA-Lesioned Dopamine Neurotoxicity.
Lu DS, Chen C, Zheng YX, Li DD, Wang GQ, Liu J, Shi J, Zhang F
Frontiers in molecular neuroscience 2018;11:155
Frontiers in molecular neuroscience 2018;11:155
NADH protect against radiation enteritis by enhancing autophagy and inhibiting inflammation through PI3K/AKT pathway.
Wang JT, Xie WQ, Liu FQ, Bi Y, Zhu XJ, Wang QE, Zheng YF
American journal of translational research 2018;10(6):1713-1721
American journal of translational research 2018;10(6):1713-1721
Naringin Dihydrochalcone Ameliorates Cognitive Deficits and Neuropathology in APP/PS1 Transgenic Mice.
Yang W, Zhou K, Zhou Y, An Y, Hu T, Lu J, Huang S, Pei G
Frontiers in aging neuroscience 2018;10:169
Frontiers in aging neuroscience 2018;10:169
Casticin prevents DSS induced ulcerative colitis in mice through inhibitions of NF-κB pathway and ROS signaling.
Ma J, Yin G, Lu Z, Xie P, Zhou H, Liu J, Yu L
Phytotherapy research : PTR 2018 Sep;32(9):1770-1783
Phytotherapy research : PTR 2018 Sep;32(9):1770-1783
Tumour YAP1 and PTEN expression correlates with tumour-associated myeloid suppressor cell expansion and reduced survival in colorectal cancer.
Yang R, Cai TT, Wu XJ, Liu YN, He J, Zhang XS, Ma G, Li J
Immunology 2018 Oct;155(2):263-272
Immunology 2018 Oct;155(2):263-272
(2R,3R)Dihydromyricetin inhibits osteoclastogenesis and bone loss through scavenging LPS-induced oxidative stress and NF-κB and MAPKs pathways activating.
Zhang X, Li X, Fang J, Hou X, Fang H, Guo F, Li F, Chen A, Huang S
Journal of cellular biochemistry 2018 Nov;119(11):8981-8995
Journal of cellular biochemistry 2018 Nov;119(11):8981-8995
Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration.
Tsarouchas TM, Wehner D, Cavone L, Munir T, Keatinge M, Lambertus M, Underhill A, Barrett T, Kassapis E, Ogryzko N, Feng Y, van Ham TJ, Becker T, Becker CG
Nature communications 2018 Nov 7;9(1):4670
Nature communications 2018 Nov 7;9(1):4670
Lysyl oxidase blockade ameliorates anovulation in polycystic ovary syndrome.
Zhang C, Ma J, Wang W, Sun Y, Sun K
Human reproduction (Oxford, England) 2018 Nov 1;33(11):2096-2106
Human reproduction (Oxford, England) 2018 Nov 1;33(11):2096-2106
Autocrine IL-1β mediates the promotion of corneal neovascularization by senescent fibroblasts.
Dong M, Yang L, Qu M, Hu X, Duan H, Zhang X, Shi W, Zhou Q
American journal of physiology. Cell physiology 2018 Nov 1;315(5):C734-C743
American journal of physiology. Cell physiology 2018 Nov 1;315(5):C734-C743
Protective effects of mitochondrion-targeted peptide SS-31 against hind limb ischemia-reperfusion injury.
Cai J, Jiang Y, Zhang M, Zhao H, Li H, Li K, Zhang X, Qiao T
Journal of physiology and biochemistry 2018 May;74(2):335-343
Journal of physiology and biochemistry 2018 May;74(2):335-343
Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
Jia YN, Lu HP, Peng YL, Zhang BS, Gong XB, Su J, Zhou Y, Pan MH, Xu L
International immunopharmacology 2018 Mar;56:105-112
International immunopharmacology 2018 Mar;56:105-112
Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats.
Wei P, Zheng Q, Liu H, Wan T, Zhou J, Li D, Zhou H, Li J, Ji F, Tang W, Li J
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2018 Mar 6;20(4):515-522
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2018 Mar 6;20(4):515-522
Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells.
Takahashi A, Loo TM, Okada R, Kamachi F, Watanabe Y, Wakita M, Watanabe S, Kawamoto S, Miyata K, Barber GN, Ohtani N, Hara E
Nature communications 2018 Mar 28;9(1):1249
Nature communications 2018 Mar 28;9(1):1249
The role of the microRNA-146a/complement factor H/interleukin-1β-mediated inflammatory loop circuit in the perpetuate inflammation of chronic temporal lobe epilepsy.
Li TR, Jia YJ, Ma C, Qiu WY, Wang Q, Shao XQ, Lv RJ
Disease models & mechanisms 2018 Mar 23;11(3)
Disease models & mechanisms 2018 Mar 23;11(3)
Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats.
Zhang J, Tucker LD, DongYan, Lu Y, Yang L, Wu C, Li Y, Zhang Q
Neurochemistry international 2018 Jun;116:1-12
Neurochemistry international 2018 Jun;116:1-12
Carbon monoxide-releasing molecule-3 protects against ischemic stroke by suppressing neuroinflammation and alleviating blood-brain barrier disruption.
Wang J, Zhang D, Fu X, Yu L, Lu Z, Gao Y, Liu X, Man J, Li S, Li N, Chen X, Hong M, Yang Q, Wang J
Journal of neuroinflammation 2018 Jun 21;15(1):188
Journal of neuroinflammation 2018 Jun 21;15(1):188
Role of Brain-Derived Neurotrophic Factor in Endometriosis Pain.
Ding S, Zhu T, Tian Y, Xu P, Chen Z, Huang X, Zhang X
Reproductive sciences (Thousand Oaks, Calif.) 2018 Jul;25(7):1045-1057
Reproductive sciences (Thousand Oaks, Calif.) 2018 Jul;25(7):1045-1057
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Lu X, Liu T, Chen K, Xia Y, Dai W, Xu S, Xu L, Wang F, Wu L, Li J, Li S, Wang W, Yu Q, Feng J, Fan X, Zhou Y, Niu P, Guo C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:800-811
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:800-811
Effects of Dandelion Extract on the Proliferation of Rat Skeletal Muscle Cells and the Inhibition of a Lipopolysaccharide-Induced Inflammatory Reaction.
Liu Q, Zhao H, Gao Y, Meng Y, Zhao XX, Pan SN
Chinese medical journal 2018 Jul 20;131(14):1724-1731
Chinese medical journal 2018 Jul 20;131(14):1724-1731
Prenatal cold stress: Effect on maternal hippocampus and offspring behavior in rats.
Lian S, Wang D, Xu B, Guo W, Wang L, Li W, Ji H, Wang J, Kong F, Zhen L, Li S, Zhang L, Guo J, Yang H
Behavioural brain research 2018 Jul 2;346:1-10
Behavioural brain research 2018 Jul 2;346:1-10
Hydrogen sulfide protects neonatal rat medulla oblongata against prenatal cigarette smoke exposure via anti-oxidative and anti-inflammatory effects.
Yan X, Lei F, Hu Y, Nie L, Jia Q, Zhou H, Zhao F, Zheng Y
Environmental toxicology and pharmacology 2018 Jan;57:151-158
Environmental toxicology and pharmacology 2018 Jan;57:151-158
Curcumin Attenuates Colistin-Induced Neurotoxicity in N2a Cells via Anti-inflammatory Activity, Suppression of Oxidative Stress, and Apoptosis.
Dai C, Ciccotosto GD, Cappai R, Tang S, Li D, Xie S, Xiao X, Velkov T
Molecular neurobiology 2018 Jan;55(1):421-434
Molecular neurobiology 2018 Jan;55(1):421-434
Vaccarin alleviates hypertension and nephropathy in renovascular hypertensive rats.
Cai W, Zhang Z, Huang Y, Sun H, Qiu L
Experimental and therapeutic medicine 2018 Jan;15(1):924-932
Experimental and therapeutic medicine 2018 Jan;15(1):924-932
Surgical incision induces learning impairment in mice partially through inhibition of the brain-derived neurotrophic factor signaling pathway in the hippocampus and amygdala.
Liu Z, Liu F, Liu X, Ma C, Zhao J
Molecular pain 2018 Jan-Dec;14:1744806918805902
Molecular pain 2018 Jan-Dec;14:1744806918805902
Mechanism of salvianolic acid B neuroprotection against ischemia/reperfusion induced cerebral injury.
Fan Y, Luo Q, Wei J, Lin R, Lin L, Li Y, Chen Z, Lin W, Chen Q
Brain research 2018 Jan 15;1679:125-133
Brain research 2018 Jan 15;1679:125-133
NF-E2-Related Factor 2 Suppresses Intestinal Fibrosis by Inhibiting Reactive Oxygen Species-Dependent TGF-β1/SMADs Pathway.
Guan Y, Tan Y, Liu W, Yang J, Wang D, Pan D, Sun Y, Zheng C
Digestive diseases and sciences 2018 Feb;63(2):366-380
Digestive diseases and sciences 2018 Feb;63(2):366-380
Telbivudine attenuates UUO-induced renal fibrosis via TGF-β/Smad and NF-κB signaling.
Chen J, Li D
International immunopharmacology 2018 Feb;55:1-8
International immunopharmacology 2018 Feb;55:1-8
Fungal β-Glucan Activates the NLRP3 Inflammasome in Human Bronchial Epithelial Cells Through ROS Production.
Huang Y, Hua M, Cui X
Inflammation 2018 Feb;41(1):164-173
Inflammation 2018 Feb;41(1):164-173
Effects of platelet-rich plasma on the activity of human menstrual blood-derived stromal cells in vitro.
Zhang S, Li P, Yuan Z, Tan J
Stem cell research & therapy 2018 Feb 26;9(1):48
Stem cell research & therapy 2018 Feb 26;9(1):48
Pyroptosis induced by enterovirus 71 and coxsackievirus B3 infection affects viral replication and host response.
Wang Y, Qin Y, Wang T, Chen Y, Lang X, Zheng J, Gao S, Chen S, Zhong X, Mu Y, Wu X, Zhang F, Zhao W, Zhong Z
Scientific reports 2018 Feb 13;8(1):2887
Scientific reports 2018 Feb 13;8(1):2887
CAPE-pNO2 attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice.
Fan L, Xiao Q, Zhang L, Wang X, Huang Q, Li S, Zhao X, Li Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1640-1650
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1640-1650
Influence of vitamin D deficiency on T cell subsets and related indices during spinal tuberculosis.
Zhou SH, Wang X, Fan MY, Li HL, Bian F, Huang T, Fang HY
Experimental and therapeutic medicine 2018 Aug;16(2):718-722
Experimental and therapeutic medicine 2018 Aug;16(2):718-722
Proteomic profiling of human decidual immune proteins during Toxoplasma gondii infection.
Zhang D, Sun X, Ren L, Yang C, Liu X, Zhang H, Jiang Y, Hu X
Journal of proteomics 2018 Aug 30;186:28-37
Journal of proteomics 2018 Aug 30;186:28-37
Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice.
Geng W, Qin F, Ren J, Xiao S, Wang A
Experimental cell research 2018 Aug 15;369(2):243-250
Experimental cell research 2018 Aug 15;369(2):243-250
Fenofibrate Exerts Protective Effects in Diabetic Retinopathy via Inhibition of the ANGPTL3 Pathway.
Wang N, Zou C, Zhao S, Wang Y, Han C, Zheng Z
Investigative ophthalmology & visual science 2018 Aug 1;59(10):4210-4217
Investigative ophthalmology & visual science 2018 Aug 1;59(10):4210-4217
Establishment of experimental autoimmune prostatitis model by T2 peptide in aluminium hydroxide adjuvant.
Zhang L, Ihsan AU, Cao Y, Cheng Y, Zhou X
Andrologia 2018 Apr;50(3)
Andrologia 2018 Apr;50(3)
Tumor-Stroma IL1β-IRAK4 Feedforward Circuitry Drives Tumor Fibrosis, Chemoresistance, and Poor Prognosis in Pancreatic Cancer.
Zhang D, Li L, Jiang H, Li Q, Wang-Gillam A, Yu J, Head R, Liu J, Ruzinova MB, Lim KH
Cancer research 2018 Apr 1;78(7):1700-1712
Cancer research 2018 Apr 1;78(7):1700-1712
Aliskiren Improves Ischemia- and Oxygen Glucose Deprivation-Induced Cardiac Injury through Activation of Autophagy and AMP-Activated Protein Kinase.
Chiang MH, Liang CJ, Liu CW, Pan BJ, Chen WP, Yang YF, Lee IT, Tsai JS, Lee CW, Chen YL
Frontiers in pharmacology 2017;8:819
Frontiers in pharmacology 2017;8:819
NLRP3 Gene Deletion Attenuates Angiotensin II-Induced Phenotypic Transformation of Vascular Smooth Muscle Cells and Vascular Remodeling.
Ren XS, Tong Y, Ling L, Chen D, Sun HJ, Zhou H, Qi XH, Chen Q, Li YH, Kang YM, Zhu GQ
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(6):2269-2280
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(6):2269-2280
Salusin-β Is Involved in Diabetes Mellitus-Induced Endothelial Dysfunction via Degradation of Peroxisome Proliferator-Activated Receptor Gamma.
Sun HJ, Chen D, Wang PY, Wan MY, Zhang CX, Zhang ZX, Lin W, Zhang F
Oxidative medicine and cellular longevity 2017;2017:6905217
Oxidative medicine and cellular longevity 2017;2017:6905217
Adulthood Exposure to Lipopolysaccharide Exacerbates the Neurotoxic and Inflammatory Effects of Rotenone in the Substantia Nigra.
Huang C, Zhu L, Li H, Shi FG, Wang GQ, Wei YZ, Liu J, Zhang F
Frontiers in molecular neuroscience 2017;10:131
Frontiers in molecular neuroscience 2017;10:131
GRP78 plays an integral role in tumor cell inflammation-related migration induced by M2 macrophages.
Zhang L, Li Z, Ding G, La X, Yang P, Li Z
Cellular signalling 2017 Sep;37:136-148
Cellular signalling 2017 Sep;37:136-148
Melatonin attenuated the brain damage and cognitive impairment partially through MT2 melatonin receptor in mice with chronic cerebral hypoperfusion.
Tsai TH, Lin CJ, Chua S, Chung SY, Yang CH, Tong MS, Hang CL
Oncotarget 2017 Sep 26;8(43):74320-74330
Oncotarget 2017 Sep 26;8(43):74320-74330
NLRP3 inflammasome activation contributes to VSMC phenotypic transformation and proliferation in hypertension.
Sun HJ, Ren XS, Xiong XQ, Chen YZ, Zhao MX, Wang JJ, Zhou YB, Han Y, Chen Q, Li YH, Kang YM, Zhu GQ
Cell death & disease 2017 Oct 5;8(10):e3074
Cell death & disease 2017 Oct 5;8(10):e3074
Role of NF-κB/GATA3 in the inhibition of lysyl oxidase by IL-1β in human amnion fibroblasts.
Zhang C, Wang W, Liu C, Lu J, Sun K
Immunology and cell biology 2017 Nov;95(10):943-952
Immunology and cell biology 2017 Nov;95(10):943-952
Neuroprotective Effect of Chitosan Oligosaccharide on Hypoxic-Ischemic Brain Damage in Neonatal Rats.
Wu W, Wei W, Lu M, Zhu X, Liu N, Niu Y, Sun T, Li Y, Yu J
Neurochemical research 2017 Nov;42(11):3186-3198
Neurochemical research 2017 Nov;42(11):3186-3198
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
Gong X, Yang Y, Huang L, Zhang Q, Wan RZ, Zhang P, Zhang B
International immunopharmacology 2017 May;46:124-132
International immunopharmacology 2017 May;46:124-132
Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.
Yang Y, Gong XB, Huang LG, Wang ZX, Wan RZ, Zhang P, Zhang QY, Chen Z, Zhang BS
Oncotarget 2017 May 9;8(19):30723-30733
Oncotarget 2017 May 9;8(19):30723-30733
Suppression of MyD88-dependent signaling alleviates neuropathic pain induced by peripheral nerve injury in the rat.
Liu F, Wang Z, Qiu Y, Wei M, Li C, Xie Y, Shen L, Huang Y, Ma C
Journal of neuroinflammation 2017 Mar 31;14(1):70
Journal of neuroinflammation 2017 Mar 31;14(1):70
Naoling decoction restores cognitive function by inhibiting the neuroinflammatory network in a rat model of Alzheimer's disease.
Xia Z, Peng W, Cheng S, Zhong B, Sheng C, Zhang C, Gong W, Cheng S, Li J, Wang Z
Oncotarget 2017 Jun 27;8(26):42648-42663
Oncotarget 2017 Jun 27;8(26):42648-42663
Global Transcriptomic Profiling of Cortex and Striatum: Cerebral Injury after Ischemia/Reperfusion in a Mouse Model.
Zhao Z, Lu Z, Sun X, Zhao T, Zhang J, Zhou C, Zheng X, Zhang H, Shi G
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2017 Jul;26(7):1622-1634
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2017 Jul;26(7):1622-1634
Rapamycin suppresses Aβ25-35- or LPS-induced neuronal inflammation via modulation of NF-κB signaling.
Liu YC, Gao XX, Chen L, You XQ
Neuroscience 2017 Jul 4;355:188-199
Neuroscience 2017 Jul 4;355:188-199
Heparanase-driven inflammation from the AGEs-stimulated macrophages changes the functions of glomerular endothelial cells.
Xu G, Qin Q, Yang M, Qiao Z, Gu Y, Niu J
Diabetes research and clinical practice 2017 Feb;124:30-40
Diabetes research and clinical practice 2017 Feb;124:30-40
Dopamine D2 receptor signalling controls inflammation in acute pancreatitis via a PP2A-dependent Akt/NF-κB signalling pathway.
Han X, Li B, Ye X, Mulatibieke T, Wu J, Dai J, Wu D, Ni J, Zhang R, Xue J, Wan R, Wang X, Hu G
British journal of pharmacology 2017 Dec;174(24):4751-4770
British journal of pharmacology 2017 Dec;174(24):4751-4770
Impact of prenatal cold stress on placental physiology, inflammatory response, and apoptosis in rats.
Lian S, Guo J, Wang L, Li W, Wang J, Ji H, Kong F, Xu B, Li S, Yang H
Oncotarget 2017 Dec 29;8(70):115304-115314
Oncotarget 2017 Dec 29;8(70):115304-115314
Possible involvement of the oxLDL/LOX-1 system in the pathogenesis and progression of human intervertebral disc degeneration or herniation.
Li X, Wang X, Hu Z, Chen Z, Li H, Liu X, Yong ZY, Wang S, Wei Z, Han Y, Tan J, Li C, He XB, Sun G, Wu D, Li L
Scientific reports 2017 Aug 7;7(1):7403
Scientific reports 2017 Aug 7;7(1):7403
Rapid allergen-induced interleukin-17 and interferon-γ secretion by skin-resident memory CD8+ T cells.
Schmidt JD, Ahlström MG, Johansen JD, Dyring-Andersen B, Agerbeck C, Nielsen MM, Poulsen SS, Woetmann A, Ødum N, Thomsen AR, Geisler C, Bonefeld CM
Contact dermatitis 2017 Apr;76(4):218-227
Contact dermatitis 2017 Apr;76(4):218-227
Inflammatory Stress Sensitizes the Liver to Atorvastatin-Induced Injury in ApoE-/- Mice.
Wu W, Zhao L, Yang P, Zhou W, Li B, Moorhead JF, Varghese Z, Ruan XZ, Chen Y
PloS one 2016;11(7):e0159512
PloS one 2016;11(7):e0159512
A recombinant TGF-β1 vaccine ameliorates diabetic nephropathy in OLETF rats.
Zhang H, Wang H, Yan M, Zhao T, Lu X, Zhu B, Gong Y, Li P
Immunotherapy 2016 Sep;8(9):1045-57
Immunotherapy 2016 Sep;8(9):1045-57
15d-PGJ2 alleviates ConA-induced acute liver injury in mice by up-regulating HO-1 and reducing hepatic cell autophagy.
Chen K, Li J, Li S, Feng J, Wu L, Liu T, Zhang R, Xu S, Cheng K, Zhou Y, Zhou S, Wang F, Dai W, Xia Y, Lu J, Zhou Y, Guo C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:183-192
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:183-192
Histone deacetylase inhibitor SAHA attenuates post-seizure hippocampal microglia TLR4/MYD88 signaling and inhibits TLR4 gene expression via histone acetylation.
Hu QP, Mao DA
BMC neuroscience 2016 May 18;17(1):22
BMC neuroscience 2016 May 18;17(1):22
New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats.
Ding C, Zhao Y, Shi X, Zhang N, Zu G, Li Z, Zhou J, Gao D, Lv L, Tian X, Yao J
Scientific reports 2016 Jun 27;6:28734
Scientific reports 2016 Jun 27;6:28734
Dendrobium officinale Kimura et Migo attenuates diabetic cardiomyopathy through inhibiting oxidative stress, inflammation and fibrosis in streptozotocin-induced mice.
Zhang Z, Zhang D, Dou M, Li Z, Zhang J, Zhao X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:1350-1358
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:1350-1358
Angiotensin(1-7) attenuated Angiotensin II-induced hepatocyte EMT by inhibiting NOX-derived H2O2-activated NLRP3 inflammasome/IL-1β/Smad circuit.
Zhang LL, Huang S, Ma XX, Zhang WY, Wang D, Jin SY, Zhang YP, Li Y, Li X
Free radical biology & medicine 2016 Aug;97:531-543
Free radical biology & medicine 2016 Aug;97:531-543
The quantum of initial transformed cells potentially modulates the type of local inflammation mechanism elicited by surrounding normal epithelial tissues and systemic immune pattern for tumor arrest or progression.
Owusu L, Wang B, Du Y, Li W, Xin Y
Journal of Cancer 2015;6(2):128-38
Journal of Cancer 2015;6(2):128-38
Expression of beclin-1 in the microenvironment of invasive ductal carcinoma of the breast: correlation with prognosis and the cancer-stromal interaction.
Morikawa A, Takeuchi T, Kito Y, Saigo C, Sakuratani T, Futamura M, Yoshida K
PloS one 2015;10(5):e0125762
PloS one 2015;10(5):e0125762
Inhibition of HMGB1 release via salvianolic acid B-mediated SIRT1 up-regulation protects rats against non-alcoholic fatty liver disease.
Zeng W, Shan W, Gao L, Gao D, Hu Y, Wang G, Zhang N, Li Z, Tian X, Xu W, Peng J, Ma X, Yao J
Scientific reports 2015 Nov 3;5:16013
Scientific reports 2015 Nov 3;5:16013
P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation.
Peng K, Liu L, Wei D, Lv Y, Wang G, Xiong W, Wang X, Altaf A, Wang L, He D, Wang H, Qu P
International journal of molecular medicine 2015 May;35(5):1179-88
International journal of molecular medicine 2015 May;35(5):1179-88
Aging increases the susceptibility of cisplatin-induced nephrotoxicity.
Wen J, Zeng M, Shu Y, Guo D, Sun Y, Guo Z, Wang Y, Liu Z, Zhou H, Zhang W
Age (Dordrecht, Netherlands) 2015 Dec;37(6):112
Age (Dordrecht, Netherlands) 2015 Dec;37(6):112
Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice.
Shi Q, Song X, Fu J, Su C, Xia X, Song E, Song Y
International immunopharmacology 2015 Dec;29(2):722-729
International immunopharmacology 2015 Dec;29(2):722-729
Impaired autophagy contributes to adverse cardiac remodeling in acute myocardial infarction.
Wu X, He L, Chen F, He X, Cai Y, Zhang G, Yi Q, He M, Luo J
PloS one 2014;9(11):e112891
PloS one 2014;9(11):e112891
Tetrachloro-p-benzoquinone induces hepatic oxidative damage and inflammatory response, but not apoptosis in mouse: the prevention of curcumin.
Xu D, Hu L, Su C, Xia X, Zhang P, Fu J, Wang W, Xu D, Du H, Hu Q, Song E, Song Y
Toxicology and applied pharmacology 2014 Oct 15;280(2):305-13
Toxicology and applied pharmacology 2014 Oct 15;280(2):305-13
Mulberroside A protects against ischemic impairment in primary culture of rat cortical neurons after oxygen-glucose deprivation followed by reperfusion.
Wang CP, Zhang LZ, Li GC, Shi YW, Li JL, Zhang XC, Wang ZW, Ding F, Liang XM
Journal of neuroscience research 2014 Jul;92(7):944-54
Journal of neuroscience research 2014 Jul;92(7):944-54
Tongxinluo inhibits vascular inflammation and neointimal hyperplasia through blockade of the positive feedback loop between miR-155 and TNF-α.
Zhang RN, Zheng B, Li LM, Zhang J, Zhang XH, Wen JK
American journal of physiology. Heart and circulatory physiology 2014 Aug 15;307(4):H552-62
American journal of physiology. Heart and circulatory physiology 2014 Aug 15;307(4):H552-62
Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation.
Yan Y, Jiang W, Spinetti T, Tardivel A, Castillo R, Bourquin C, Guarda G, Tian Z, Tschopp J, Zhou R
Immunity 2013 Jun 27;38(6):1154-63
Immunity 2013 Jun 27;38(6):1154-63
NDGA reduces secondary damage after spinal cord injury in rats via anti-inflammatory effects.
Xue H, Zhang XY, Liu JM, Song Y, Liu TT, Chen D
Brain research 2013 Jun 21;1516:83-92
Brain research 2013 Jun 21;1516:83-92
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 16806-1-AP( IL1B Antibody) at dilution of 1:700
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human adrenal gland tissue were subjected to SDS PAGE followed by western blot with 16806-1-AP(IL1B antibody) at dilution of 1:100
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skin using 16806-1-AP(IL1B antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IL1 beta antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human IL1 beta. This antibody recognizes human,mouse,rat antigen. The IL1 beta antibody has been validated for the following applications: ELISA, IHC, WB analysis.