Antibody data
- Antibody Data
- Antigen structure
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- Validations
- ELISA [1]
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- Product number
- Ab175856 - Provider product page
- Provider
- Aladdin Scientific
- Product name
- Gevokizumab (anti-IL-1b)
- Antibody type
- Recombinant
- Description
- Gevokizumab (anti-IL-1b) is a potent anti-IL-1_ antibody, negatively modulates IL-1_ signaling through an allosteric mechanism. Gevokizumab (anti-IL-1b) selectively decreases the binding affinity of IL-1_ for the IL-1 receptor type I (IL-1RI) signaling receptor instead of IL-1 counter-regulatory decoy receptor (IL-1 receptor type II).Purity>95% (SDS-PAGE&SEC)Endotoxin Level< 1.0EU/mg
- Reactivity
- Human
- Conjugate
- Unconjugated
- Vial size
- 100_g,10mg,1mg,5mg
- Concentration
- Lot by Lot
- Storage
- Store at -80_ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
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Supportive validation
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- Aladdin Scientific (provider)
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- Experimental details
- Gevokizumab (anti-IL-1b) (Ab175856) - ELISA Immobilized Recombinant Human IL-1 beta Protein (rp147346) at 1.0 μg/mL can bind Gevokizumab (anti-IL-1b) (Ab175856) with the EC₅₀ of 56.74 ng/mL.