MYO9B
gene productCELIAC4
This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Featured antibodies
 Sigma-Aldrich |
 SAB2500667 |
0 references | Polyclonal |
EL
|
 Biorbyt |
orb19278 |
0 references | Polyclonal |
WB
EL
|
Antibodies
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