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- References [9]
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- Product number
- 12432-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12432-1-AP, RRID:AB_2148635
- Product name
- MYO9B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MYO9B antibody (Cat. #12432-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The myosin and RhoGAP MYO9B influences osteocyte dendrite growth and responses to mechanical stimuli.
Myo9b mutations are associated with altered dendritic cell functions and increased susceptibility to autoimmune diabetes onset.
Mutations in MYO9B are associated with Charcot-Marie-Tooth disease type 2 neuropathies and isolated optic atrophy.
The RhoA regulators Myo9b and GEF-H1 are targets of cyclic nucleotide-dependent kinases in platelets.
TSAd Plays a Major Role in Myo9b-Mediated Suppression of Malignant Pleural Effusion by Regulating T(H)1/T(H)17 Cell Response.
The RhoGAP Myo9b Promotes Bone Growth by Mediating Osteoblastic Responsiveness to IGF-1.
Noncanonical Myo9b-RhoGAP Accelerates RhoA GTP Hydrolysis by a Dual-Arginine-Finger Mechanism.
Specific Myosins Control Actin Organization, Cell Morphology, and Migration in Prostate Cancer Cells.
The RhoGAP activity of myosin IXB is critical for osteoclast podosome patterning, motility, and resorptive capacity.
Lee BS, Murray C, Liu J, Kim M, Hwang MS, Yueh T, Mansour M, Qamar S, Agarwal G, Kim DG
Frontiers in bioengineering and biotechnology 2023;11:1243303
Frontiers in bioengineering and biotechnology 2023;11:1243303
Myo9b mutations are associated with altered dendritic cell functions and increased susceptibility to autoimmune diabetes onset.
Zhang J, Zou Y, Chen L, Sun F, Xu Q, Zhou Q, Wang Y, Luo X, Wang N, Li Y, Zhang S, Xiong F, Yang P, Liu S, Yang T, Weng J, Eizirik DL, Yan J, Zhou Z, Wang CY
Nature communications 2023 Sep 25;14(1):5977
Nature communications 2023 Sep 25;14(1):5977
Mutations in MYO9B are associated with Charcot-Marie-Tooth disease type 2 neuropathies and isolated optic atrophy.
Cipriani S, Guerrero-Valero M, Tozza S, Zhao E, Vollmer V, Beijer D, Danzi M, Rivellini C, Lazarevic D, Pipitone GB, Grosz BR, Lamperti C, Marzoli SB, Carrera P, Devoto M, Pisciotta C, Pareyson D, Kennerson M, Previtali SC, Zuchner S, Scherer SS, Manganelli F, Bähler M, Bolino A
European journal of neurology 2023 Feb;30(2):511-526
European journal of neurology 2023 Feb;30(2):511-526
The RhoA regulators Myo9b and GEF-H1 are targets of cyclic nucleotide-dependent kinases in platelets.
Comer S, Nagy Z, Bolado A, von Kriegsheim A, Gambaryan S, Walter U, Pagel O, Zahedi RP, Jurk K, Smolenski A
Journal of thrombosis and haemostasis : JTH 2020 Nov;18(11):3002-3012
Journal of thrombosis and haemostasis : JTH 2020 Nov;18(11):3002-3012
TSAd Plays a Major Role in Myo9b-Mediated Suppression of Malignant Pleural Effusion by Regulating T(H)1/T(H)17 Cell Response.
Yi FS, Zhang X, Zhai K, Huang ZY, Wu XZ, Wu MT, Shi XY, Pei XB, Dong SF, Wang W, Yang Y, Du J, Luo ZT, Shi HZ
Journal of immunology (Baltimore, Md. : 1950) 2020 Nov 15;205(10):2926-2935
Journal of immunology (Baltimore, Md. : 1950) 2020 Nov 15;205(10):2926-2935
The RhoGAP Myo9b Promotes Bone Growth by Mediating Osteoblastic Responsiveness to IGF-1.
McMichael BK, Jeong YH, Auerbach JA, Han CM, Sedlar R, Shettigar V, Bähler M, Agarwal S, Kim DG, Lee BS
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2017 Oct;32(10):2103-2115
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2017 Oct;32(10):2103-2115
Noncanonical Myo9b-RhoGAP Accelerates RhoA GTP Hydrolysis by a Dual-Arginine-Finger Mechanism.
Yi F, Kong R, Ren J, Zhu L, Lou J, Wu JY, Feng W
Journal of molecular biology 2016 Jul 31;428(15):3043-57
Journal of molecular biology 2016 Jul 31;428(15):3043-57
Specific Myosins Control Actin Organization, Cell Morphology, and Migration in Prostate Cancer Cells.
Makowska KA, Hughes RE, White KJ, Wells CM, Peckham M
Cell reports 2015 Dec 15;13(10):2118-25
Cell reports 2015 Dec 15;13(10):2118-25
The RhoGAP activity of myosin IXB is critical for osteoclast podosome patterning, motility, and resorptive capacity.
McMichael BK, Scherer KF, Franklin NC, Lee BS
PloS one 2014;9(1):e87402
PloS one 2014;9(1):e87402
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MYO9B antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MYO9B. This antibody recognizes human, mouse, rat antigen. The MYO9B antibody has been validated for the following applications: ELISA, WB analysis.
