ABIN371655

antibody from antibodies-online

Targeting: MMP2 CLG4, CLG4A, TBE-1

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN371655

Provider

antibodies-online

Product name

anti-Matrix Metalloproteinase 2 (MMP2) antibody

Antibody type

Monoclonal

Description

Purified

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

SB13a

Vial size

0.1 mg

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.Shelf life: one year from despatch.

References

Submitted references

Exposure of cryptic domains in the alpha 1-chain of laminin-1 by elastase stimulates macrophages urokinase and matrix metalloproteinase-9 expression.

Faisal Khan KM, Laurie GW, McCaffrey TA, Falcone DJ
The Journal of biological chemistry 2002 Apr 19;277(16):13778-86

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Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5.

Giannelli G, Falk-Marzillier J, Schiraldi O, Stetler-Stevenson WG, Quaranta V
Science (New York, N.Y.) 1997 Jul 11;277(5323):225-8

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Cellular mechanisms for human procollagenase-3 (MMP-13) activation. Evidence that MT1-MMP (MMP-14) and gelatinase a (MMP-2) are able to generate active enzyme.

Knäuper V, Will H, López-Otin C, Smith B, Atkinson SJ, Stanton H, Hembry RM, Murphy G
The Journal of biological chemistry 1996 Jul 19;271(29):17124-31

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Extracellular matrix binding properties of recombinant fibronectin type II-like modules of human 72-kDa gelatinase/type IV collagenase. High affinity binding to native type I collagen but not native type IV collagen.

Steffensen B, Wallon UM, Overall CM
The Journal of biological chemistry 1995 May 12;270(19):11555-66

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Matrix metalloproteinase-2 is an interstitial collagenase. Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type I collagen generating the specific 3/4- and 1/4-length fragments.

Aimes RT, Quigley JP
The Journal of biological chemistry 1995 Mar 17;270(11):5872-6

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Activation of progelatinase B (MMP-9) by gelatinase A (MMP-2).

Fridman R, Toth M, Peña D, Mobashery S
Cancer research 1995 Jun 15;55(12):2548-55

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Degradation of the COL1 domain of type XIV collagen by 92-kDa gelatinase.

Sires UI, Dublet B, Aubert-Foucher E, van der Rest M, Welgus HG
The Journal of biological chemistry 1995 Jan 20;270(3):1062-7

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Matrix metalloproteinases degrade myelin basic protein.

Chandler S, Coates R, Gearing A, Lury J, Wells G, Bone E
Neuroscience letters 1995 Dec 15;201(3):223-6

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Human 92- and 72-kilodalton type IV collagenases are elastases.

Senior RM, Griffin GL, Fliszar CJ, Shapiro SD, Goldberg GI, Welgus HG
The Journal of biological chemistry 1991 Apr 25;266(12):7870-5

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Cleavage of type VII collagen by interstitial collagenase and type IV collagenase (gelatinase) derived from human skin.

Seltzer JL, Eisen AZ, Bauer EA, Morris NP, Glanville RW, Burgeson RE
The Journal of biological chemistry 1989 Mar 5;264(7):3822-6

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H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.

Collier IE, Wilhelm SM, Eisen AZ, Marmer BL, Grant GA, Seltzer JL, Kronberger A, He CS, Bauer EA, Goldberg GI
The Journal of biological chemistry 1988 May 15;263(14):6579-87