Tissue expression
Cell line expression

SERPINC1

gene product
AT3, ATIII, MGC22579 
The protein encoded by this gene, antithrombin III, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. Numerous mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency which constitutes a strong risk factor for thrombosis. A reduction in the serum level of this protein is associated with severe cases of Coronavirus Disease 19 (COVID-19). [provided by RefSeq, Sep 2020]
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867 antibodies from 41 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
28 antibodies
Proteintech Group
2 antibodies
Biorbyt
37 antibodies
GeneTex
14 antibodies
NSJ Bioreagents
4 antibodies
OriGene
14 antibodies
Abgent
6 antibodies
Arigo
1 antibody
Novus Biologicals
83 antibodies
antibodies-online
269 antibodies
LifeSpan BioSciences, Inc.
143 antibodies
R&D Systems
3 antibodies
HUABIO Research
3 antibodies
ProSci
3 antibodies
Bioworld Technology, Inc
2 antibodies
Cusabio Biotech Co., Ltd
7 antibodies
Aviva Systems Biology
6 antibodies
NovoPro Bioscience Inc.
2 antibodies
Affinity Biosciences
1 antibody
Abnova Corporation
12 antibodies
Atlas Antibodies
2 antibodies
Wuhan Fine Biotech Co., Ltd.
2 antibodies
Acris Antibodies GmbH
8 antibodies
Boster Biological Technology
2 antibodies
MyBioSource
30 antibodies
RabMAbs
4 antibodies
Creative Diagnostics
19 antibodies
Leading Biology
7 antibodies
United States Biological
57 antibodies
Abbexa
14 antibodies
Creative Biolabs
34 antibodies
RayBiotech, Inc.
2 antibodies
Molecular Innovations
6 antibodies
GenWay
8 antibodies
Abbiotec
4 antibodies
MilliporeSigma / Merck KGaA
6 antibodies
Green Mountain Antibodies
1 antibody
Sino Biological Inc.
3 antibodies
Aalto Bio Reagents Ltd.
1 antibody
Rockland Immunochemicals, Inc.
1 antibody