XAGE2

This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in normal testis, and in Ewing's sarcoma, rhabdomyosarcoma, a breast cancer and a germ cell tumor. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. [provided by RefSeq, Jul 2008]

Description

X antigen family member 2

Tissue specificity

Tissue enriched (placenta)

Subcell location

Vesicles, Plasma membrane

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

X (52369021 - 52375680)

Ensembl ID

ENSG00000155622  (ver. 103.38)

Orthologs

-

UniProt

Q96GT9

neXtProt

NX_Q96GT9

Human splice variants

Protein structure