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Flow cytometry
Other assayAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 301337 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#301337, RRID:AB_2562811
- Product name
- Purified anti-human CD11b (MaxPar® Ready)
- Antibody type
- Monoclonal
- Antigen
- 0
- Description
- CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αM integrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2 (CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and Factor X.
- Reactivity
- Human, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- ICRF44
- Vial size
- 100 µg
- Concentration
- 1 mg/ml
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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- BioLegend (provider)
- Main image
- Experimental details
- Human PBMCs stained with 144Nd-anti-CD11b (ICRF44). T lymphocytes (bottom) and monocytes (top) are displayed in the analysis.
- Conjugate
- Unconjugated
