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Protein structure
ITGAM
Integrin subunit alpha MCD11B, CR3A, MAC-1
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Top validated antibodies |
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| Novus Biologicals |  NB100-2623 |
2 references | Monoclonal |
WB
ICC
IP
IHC
FC
RA
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| antibodies-online | ABIN258322 |
17 references | Polyclonal |
WB
ICC
IHC
FC
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| GeneTex | GTX42473 |
2 references | Monoclonal |
ICC
IP
IHC
FC
FA
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| Invitrogen Antibodies | PA5-90724 |
3 references | Polyclonal |
WB
ICC
IHC
OA
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| Boster Biological Technology | A00144-1 |
1 references | Polyclonal |
WB
EL
ICC
IHC
FC
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