ABIN1690733

antibody from antibodies-online

Targeting: ITGAM CD11B, CR3A, MAC-1

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

ABIN1690733

Provider

antibodies-online

Product name

anti-Integrin alpha M (ITGAM) antibody (APC)

Antibody type

Monoclonal

Antigen

B10 mouse spleen cells enriched for T cells

Reactivity

Human, Mouse, Rabbit, Simian

Host

Rat

Isotype

IgG

Antibody clone number

M1-70

Vial size

0.1 mg

Storage

Do not freeze. Avoid prolonged exposure to light.

References

Submitted references

Cooperation of specific ICAM-3 grabbing nonintegrin-related 1 (SIGNR1) and complement receptor type 3 (CR3) in the uptake of oligomannose-coated liposomes by macrophages.

Takagi H, Numazaki M, Kajiwara T, Abe Y, Ishii M, Kato C, Kojima N
Glycobiology 2009 Mar;19(3):258-66

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Antibodies to complement receptor 3 treat established inflammation in murine models of colitis and a novel model of psoriasiform dermatitis.

Leon F, Contractor N, Fuss I, Marth T, Lahey E, Iwaki S, la Sala A, Hoffmann V, Strober W, Kelsall BL
Journal of immunology (Baltimore, Md. : 1950) 2006 Nov 15;177(10):6974-82

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M1/70 attenuates blood-borne neutrophil oxidants, activation, and myofiber damage following stretch injury.

Brickson S, Ji LL, Schell K, Olabisi R, St Pierre Schneider B, Best TM
Journal of applied physiology (Bethesda, Md. : 1985) 2003 Sep;95(3):969-76

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Murine sclerodermatous graft-versus-host disease, a model for human scleroderma: cutaneous cytokines, chemokines, and immune cell activation.

Zhang Y, McCormick LL, Desai SR, Wu C, Gilliam AC
Journal of immunology (Baltimore, Md. : 1950) 2002 Mar 15;168(6):3088-98

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Dendritic cells purified from myeloma are primed with tumor-specific antigen (idiotype) and activate CD4+ T cells.

Dembic Z, Schenck K, Bogen B
Proceedings of the National Academy of Sciences of the United States of America 2000 Mar 14;97(6):2697-702

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Neutrophil, not macrophage, infiltration precedes neointimal thickening in balloon-injured arteries.

Welt FG, Edelman ER, Simon DI, Rogers C
Arteriosclerosis, thrombosis, and vascular biology 2000 Dec;20(12):2553-8

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Immunohistochemical detection of T-cell subsets and other leukocytes in paraffin-embedded rat and mouse tissues with monoclonal antibodies.

Whiteland JL, Nicholls SM, Shimeld C, Easty DL, Williams NA, Hill TJ
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1995 Mar;43(3):313-20

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Mapping of antigenic and functional epitopes on the alpha- and beta-subunits of two related mouse glycoproteins involved in cell interactions, LFA-1 and Mac-1.

Sanchez-Madrid F, Simon P, Thompson S, Springer TA
The Journal of experimental medicine 1983 Aug 1;158(2):586-602

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Cross-reaction of a rat-anti-mouse phagocyte-specific monoclonal antibody (anti-Mac-1) with human monocytes and natural killer cells.

Ault KA, Springer TA
Journal of immunology (Baltimore, Md. : 1950) 1981 Jan;126(1):359-64

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Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens.

Springer T, Galfrè G, Secher DS, Milstein C
European journal of immunology 1978 Aug;8(8):539-51