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Immunocytochemistry
Other assayAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Other assay [1]
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- Product number
- V2161 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- CD11b Antibody
- Antibody type
- Monoclonal
- Antigen
- B10 mouse spleen cells enriched for T lymphocytes were used as the immunogen for this CD11b antibody.
- Description
- Protein G purified antibody
- Reactivity
- Human, Rabbit
- Host
- Rat
- Conjugate
- Unconjugated
- Antibody clone number
- M1/70
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the CD11b antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references Hemarthrosis in hemophilic mice results in alterations in M1-M2 monocyte/macrophage polarization.
Contributions of thrombin targets to tissue factor-dependent metastasis in hyperthrombotic mice.
Temporal and spatial characterization of mononuclear phagocytes in circulating, lung alveolar and interstitial compartments in a mouse model of bleomycin-induced pulmonary injury.
Kruppel-like transcription factor 6 regulates inflammatory macrophage polarization.
M1/70 attenuates blood-borne neutrophil oxidants, activation, and myofiber damage following stretch injury.
A mAb to the beta2-leukocyte integrin Mac-1 (CD11b/CD18) reduces intimal thickening after angioplasty or stent implantation in rabbits.
Neutrophil emigration in the skin, lungs, and peritoneum: different requirements for CD11/CD18 revealed by CD18-deficient mice.
Group B streptococcus-induced nitric oxide production in murine macrophages is CR3 (CD11b/CD18) dependent.
The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodies.
A unique recognition site mediates the interaction of fibrinogen with the leukocyte integrin Mac-1 (CD11b/CD18).
The cell surface glycoprotein Mac-1 (CD11b/CD18) mediates neutrophil adhesion and modulates degranulation independently of its quantitative cell surface expression.
Nieuwenhuizen L, Schutgens RE, Coeleveld K, Mastbergen SC, Roosendaal G, Biesma DH, Lafeber FP
Thrombosis research 2014 Mar;133(3):390-5
Thrombosis research 2014 Mar;133(3):390-5
Contributions of thrombin targets to tissue factor-dependent metastasis in hyperthrombotic mice.
Yokota N, Zarpellon A, Chakrabarty S, Bogdanov VY, Gruber A, Castellino FJ, Mackman N, Ellies LG, Weiler H, Ruggeri ZM, Ruf W
Journal of thrombosis and haemostasis : JTH 2014 Jan;12(1):71-81
Journal of thrombosis and haemostasis : JTH 2014 Jan;12(1):71-81
Temporal and spatial characterization of mononuclear phagocytes in circulating, lung alveolar and interstitial compartments in a mouse model of bleomycin-induced pulmonary injury.
Ji WJ, Ma YQ, Zhou X, Zhang YD, Lu RY, Sun HY, Guo ZZ, Zhang Z, Li YM, Wei LQ
Journal of immunological methods 2014 Jan 31;403(1-2):7-16
Journal of immunological methods 2014 Jan 31;403(1-2):7-16
Kruppel-like transcription factor 6 regulates inflammatory macrophage polarization.
Date D, Das R, Narla G, Simon DI, Jain MK, Mahabeleshwar GH
The Journal of biological chemistry 2014 Apr 11;289(15):10318-29
The Journal of biological chemistry 2014 Apr 11;289(15):10318-29
M1/70 attenuates blood-borne neutrophil oxidants, activation, and myofiber damage following stretch injury.
Brickson S, Ji LL, Schell K, Olabisi R, St Pierre Schneider B, Best TM
Journal of applied physiology (Bethesda, Md. : 1985) 2003 Sep;95(3):969-76
Journal of applied physiology (Bethesda, Md. : 1985) 2003 Sep;95(3):969-76
A mAb to the beta2-leukocyte integrin Mac-1 (CD11b/CD18) reduces intimal thickening after angioplasty or stent implantation in rabbits.
Rogers C, Edelman ER, Simon DI
Proceedings of the National Academy of Sciences of the United States of America 1998 Aug 18;95(17):10134-9
Proceedings of the National Academy of Sciences of the United States of America 1998 Aug 18;95(17):10134-9
Neutrophil emigration in the skin, lungs, and peritoneum: different requirements for CD11/CD18 revealed by CD18-deficient mice.
Mizgerd JP, Kubo H, Kutkoski GJ, Bhagwan SD, Scharffetter-Kochanek K, Beaudet AL, Doerschuk CM
The Journal of experimental medicine 1997 Oct 20;186(8):1357-64
The Journal of experimental medicine 1997 Oct 20;186(8):1357-64
Group B streptococcus-induced nitric oxide production in murine macrophages is CR3 (CD11b/CD18) dependent.
Goodrum KJ, McCormick LL, Schneider B
Infection and immunity 1994 Aug;62(8):3102-7
Infection and immunity 1994 Aug;62(8):3102-7
The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodies.
Metlay JP, Witmer-Pack MD, Agger R, Crowley MT, Lawless D, Steinman RM
The Journal of experimental medicine 1990 May 1;171(5):1753-71
The Journal of experimental medicine 1990 May 1;171(5):1753-71
A unique recognition site mediates the interaction of fibrinogen with the leukocyte integrin Mac-1 (CD11b/CD18).
Altieri DC, Agbanyo FR, Plescia J, Ginsberg MH, Edgington TS, Plow EF
The Journal of biological chemistry 1990 Jul 25;265(21):12119-22
The Journal of biological chemistry 1990 Jul 25;265(21):12119-22
The cell surface glycoprotein Mac-1 (CD11b/CD18) mediates neutrophil adhesion and modulates degranulation independently of its quantitative cell surface expression.
Schleiffenbaum B, Moser R, Patarroyo M, Fehr J
Journal of immunology (Baltimore, Md. : 1950) 1989 May 15;142(10):3537-45
Journal of immunology (Baltimore, Md. : 1950) 1989 May 15;142(10):3537-45
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Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- SDS-PAGE Analysis of Purified, BSA-Free CD11b Antibody (clone M1/70). Confirmation of Integrity and Purity of the Antibody.
