301310

ITGAM antibody from BioLegend
CD11B, CR3A, MAC-1

Antibody data

Product number
301310
Provider
BioLegend
Proper citation
BioLegend Cat#301310, RRID:AB_314162
Product name
APC anti-human CD11b
Provider product page
BioLegend - 301310
Antibody type
Monoclonal
Antigen
CD11b
Description
CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αM integrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2 (CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and Factor X.
Reactivity
Human, Porcine, Simian
Host
Mouse
Conjugate
Red dye
Isotype
IgG
Vial size
100 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Provider Type Product Number
- No reagents -