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- Antibody Data
- Antigen structure
- References [11]
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- Western blot [1]
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- Product number
- 22063-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22063-1-AP, RRID:AB_2619668
- Product name
- PDE6B antibody
- Antibody type
- Polyclonal
- Description
- PDE6B antibody (Cat. #22063-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Multi-omic insight into the molecular mechanism of cuproptosis-related genes in the pathogenesis of Parkinson's disease.
Precise Correction of the Pde6b-L659P Mutation Causing Retinal Degeneration with Minimum Bystander Editing by Advanced Genome Editing Tools.
Lack of retinal degeneration in a Dram2 knockout mouse model.
Construction and Identification of a Novel Mice Model of Microphthalmia.
Deletion of Emc1 in photoreceptor cells causes retinal degeneration in mice.
Retinoic acid delays initial photoreceptor differentiation and results in a highly structured mature retinal organoid.
Differential requirement of NPHP1 for compartmentalized protein localization during photoreceptor outer segment development and maintenance.
The myosin-tail homology domain of centrosomal protein 290 is essential for protein confinement between the inner and outer segments in photoreceptors.
Luteinizing hormone signaling phosphorylates and activates the cyclic GMP phosphodiesterase PDE5 in mouse ovarian follicles, contributing an additional component to the hormonally induced decrease in cyclic GMP that reinitiates meiosis.
Pathogenic mutations in retinitis pigmentosa 2 predominantly result in loss of RP2 protein stability in humans and zebrafish.
Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.
Zhang T, Wang Y
NPJ Parkinson's disease 2026 Jan 15;12(1):39
NPJ Parkinson's disease 2026 Jan 15;12(1):39
Precise Correction of the Pde6b-L659P Mutation Causing Retinal Degeneration with Minimum Bystander Editing by Advanced Genome Editing Tools.
Liu Z, Chen S, Sun Y
Research (Washington, D.C.) 2025;8:0770
Research (Washington, D.C.) 2025;8:0770
Lack of retinal degeneration in a Dram2 knockout mouse model.
Sun K, Chen J, Fan Y, Cai J, Jiang X, Liu W, Zhu X
Vision research 2025 Jan;226:108509
Vision research 2025 Jan;226:108509
Construction and Identification of a Novel Mice Model of Microphthalmia.
Li D, Cheng K, Zhu X
Translational vision science & technology 2024 Jul 1;13(7):11
Translational vision science & technology 2024 Jul 1;13(7):11
Deletion of Emc1 in photoreceptor cells causes retinal degeneration in mice.
Li X, Jiang Z, Su Y, Wang K, Jiang X, Sun K, Yang Y, Zhou Y, Zhu X, Zhang L
The FEBS journal 2023 Sep;290(17):4356-4370
The FEBS journal 2023 Sep;290(17):4356-4370
Retinoic acid delays initial photoreceptor differentiation and results in a highly structured mature retinal organoid.
Sanjurjo-Soriano C, Erkilic N, Damodar K, Boukhaddaoui H, Diakatou M, Garita-Hernandez M, Mamaeva D, Dubois G, Jazouli Z, Jimenez-Medina C, Goureau O, Meunier I, Kalatzis V
Stem cell research & therapy 2022 Sep 16;13(1):478
Stem cell research & therapy 2022 Sep 16;13(1):478
Differential requirement of NPHP1 for compartmentalized protein localization during photoreceptor outer segment development and maintenance.
Datta P, Cribbs JT, Seo S
PloS one 2021;16(5):e0246358
PloS one 2021;16(5):e0246358
The myosin-tail homology domain of centrosomal protein 290 is essential for protein confinement between the inner and outer segments in photoreceptors.
Datta P, Hendrickson B, Brendalen S, Ruffcorn A, Seo S
The Journal of biological chemistry 2019 Dec 13;294(50):19119-19136
The Journal of biological chemistry 2019 Dec 13;294(50):19119-19136
Luteinizing hormone signaling phosphorylates and activates the cyclic GMP phosphodiesterase PDE5 in mouse ovarian follicles, contributing an additional component to the hormonally induced decrease in cyclic GMP that reinitiates meiosis.
Egbert JR, Yee SP, Jaffe LA
Developmental biology 2018 Mar 1;435(1):6-14
Developmental biology 2018 Mar 1;435(1):6-14
Pathogenic mutations in retinitis pigmentosa 2 predominantly result in loss of RP2 protein stability in humans and zebrafish.
Liu F, Qin Y, Yu S, Soares DC, Yang L, Weng J, Li C, Gao M, Lu Z, Hu X, Liu X, Jiang T, Liu JY, Shu X, Tang Z, Liu M
The Journal of biological chemistry 2017 Apr 14;292(15):6225-6239
The Journal of biological chemistry 2017 Apr 14;292(15):6225-6239
Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.
Datta P, Allamargot C, Hudson JS, Andersen EK, Bhattarai S, Drack AV, Sheffield VC, Seo S
Proceedings of the National Academy of Sciences of the United States of America 2015 Aug 11;112(32):E4400-9
Proceedings of the National Academy of Sciences of the United States of America 2015 Aug 11;112(32):E4400-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PDE6B antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PDE6B. This antibody recognizes human, mouse antigen. The PDE6B antibody has been validated for the following applications: ELISA, WB analysis.
