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- Antibody Data
- Antigen structure
- References [5]
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- Western blot [1]
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- Product number
- 22063-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22063-1-AP, RRID:AB_2619668
- Product name
- PDE6B antibody
- Antibody type
- Polyclonal
- Description
- PDE6B antibody (Cat. #22063-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Differential requirement of NPHP1 for compartmentalized protein localization during photoreceptor outer segment development and maintenance.
The myosin-tail homology domain of centrosomal protein 290 is essential for protein confinement between the inner and outer segments in photoreceptors.
Luteinizing hormone signaling phosphorylates and activates the cyclic GMP phosphodiesterase PDE5 in mouse ovarian follicles, contributing an additional component to the hormonally induced decrease in cyclic GMP that reinitiates meiosis.
Pathogenic mutations in retinitis pigmentosa 2 predominantly result in loss of RP2 protein stability in humans and zebrafish.
Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.
Datta P, Cribbs JT, Seo S
PloS one 2021;16(5):e0246358
PloS one 2021;16(5):e0246358
The myosin-tail homology domain of centrosomal protein 290 is essential for protein confinement between the inner and outer segments in photoreceptors.
Datta P, Hendrickson B, Brendalen S, Ruffcorn A, Seo S
The Journal of biological chemistry 2019 Dec 13;294(50):19119-19136
The Journal of biological chemistry 2019 Dec 13;294(50):19119-19136
Luteinizing hormone signaling phosphorylates and activates the cyclic GMP phosphodiesterase PDE5 in mouse ovarian follicles, contributing an additional component to the hormonally induced decrease in cyclic GMP that reinitiates meiosis.
Egbert JR, Yee SP, Jaffe LA
Developmental biology 2018 Mar 1;435(1):6-14
Developmental biology 2018 Mar 1;435(1):6-14
Pathogenic mutations in retinitis pigmentosa 2 predominantly result in loss of RP2 protein stability in humans and zebrafish.
Liu F, Qin Y, Yu S, Soares DC, Yang L, Weng J, Li C, Gao M, Lu Z, Hu X, Liu X, Jiang T, Liu JY, Shu X, Tang Z, Liu M
The Journal of biological chemistry 2017 Apr 14;292(15):6225-6239
The Journal of biological chemistry 2017 Apr 14;292(15):6225-6239
Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.
Datta P, Allamargot C, Hudson JS, Andersen EK, Bhattarai S, Drack AV, Sheffield VC, Seo S
Proceedings of the National Academy of Sciences of the United States of America 2015 Aug 11;112(32):E4400-9
Proceedings of the National Academy of Sciences of the United States of America 2015 Aug 11;112(32):E4400-9
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The PDE6B antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PDE6B. This antibody recognizes human, mouse antigen. The PDE6B antibody has been validated for the following applications: ELISA, WB analysis.
