BS8599

antibody from Bioworld Technology, Inc
Targeting: PDE6B CSNB3, CSNBAD2, PDEB, rd1, RP40
Provider product page for BS8599
Western blot
Immunohistochemistry

Antibody data

Product number
BS8599 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PDE6B polyclonal antibody
Antibody type
Polyclonal
Antigen
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta; GMP-PDE beta; PDE6B; PDEB
Description
Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PDE6B protein structure - BS8599 shown in red.