Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BS8599 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- PDE6B polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta; GMP-PDE beta; PDE6B; PDEB
- Description
- Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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