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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [11]
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- Product number
- ABIN387826 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) antibody
- Antibody type
- Monoclonal
- Antigen
- This IKK beta antibody was raised using purified His-tagged recombinant full length human IKK beta.
- Description
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 62AT216
- Vial size
- 400 μL
- Concentration
- 0.65 mg/mL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Submitted references Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia.
TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO-IKK supramolecular structures.
Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency.
Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls.
Respiratory syncytial virus-mediated NF-kappa B p65 phosphorylation at serine 536 is dependent on RIG-I, TRAF6, and IKK beta.
Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF{kappa}B signalling pathways.
Protein phosphatase 2A acts as a mitogen-activated protein kinase kinase kinase 3 (MEKK3) phosphatase to inhibit lysophosphatidic acid-induced IkappaB kinase beta/nuclear factor-kappaB activation.
Downregulation of active IKK beta by Ro52-mediated autophagy.
Role of Src signal transduction pathways in scatter factor-mediated cellular protection.
Negative feedback loop in T cell activation through IkappaB kinase-induced phosphorylation and degradation of Bcl10.
Iron-mediated H2O2 production as a mechanism for cell type-specific inhibition of tumor necrosis factor alpha-induced but not interleukin-1beta-induced IkappaB kinase complex/nuclear factor-kappaB activation.
Boisson B, Laplantine E, Dobbs K, Cobat A, Tarantino N, Hazen M, Lidov HG, Hopkins G, Du L, Belkadi A, Chrabieh M, Itan Y, Picard C, Fournet JC, Eibel H, Tsitsikov E, Pai SY, Abel L, Al-Herz W, Casanova JL, Israel A, Notarangelo LD
The Journal of experimental medicine 2015 Jun 1;212(6):939-51
The Journal of experimental medicine 2015 Jun 1;212(6):939-51
TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO-IKK supramolecular structures.
Tarantino N, Tinevez JY, Crowell EF, Boisson B, Henriques R, Mhlanga M, Agou F, Israël A, Laplantine E
The Journal of cell biology 2014 Jan 20;204(2):231-45
The Journal of cell biology 2014 Jan 20;204(2):231-45
Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency.
Boisson B, Laplantine E, Prando C, Giliani S, Israelsson E, Xu Z, Abhyankar A, Israël L, Trevejo-Nunez G, Bogunovic D, Cepika AM, MacDuff D, Chrabieh M, Hubeau M, Bajolle F, Debré M, Mazzolari E, Vairo D, Agou F, Virgin HW, Bossuyt X, Rambaud C, Facchetti F, Bonnet D, Quartier P, Fournet JC, Pascual V, Chaussabel D, Notarangelo LD, Puel A, Israël A, Casanova JL, Picard C
Nature immunology 2012 Dec;13(12):1178-86
Nature immunology 2012 Dec;13(12):1178-86
Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls.
Schuurhof A, Bont L, Siezen CL, Hodemaekers H, van Houwelingen HC, Kimman TG, Hoebee B, Kimpen JL, Janssen R
Pediatric pulmonology 2010 Jun;45(6):608-13
Pediatric pulmonology 2010 Jun;45(6):608-13
Respiratory syncytial virus-mediated NF-kappa B p65 phosphorylation at serine 536 is dependent on RIG-I, TRAF6, and IKK beta.
Yoboua F, Martel A, Duval A, Mukawera E, Grandvaux N
Journal of virology 2010 Jul;84(14):7267-77
Journal of virology 2010 Jul;84(14):7267-77
Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF{kappa}B signalling pathways.
Potter C, Cordell HJ, Barton A, Daly AK, Hyrich KL, Mann DA, Morgan AW, Wilson AG, Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS), Isaacs JD
Annals of the rheumatic diseases 2010 Jul;69(7):1315-20
Annals of the rheumatic diseases 2010 Jul;69(7):1315-20
Protein phosphatase 2A acts as a mitogen-activated protein kinase kinase kinase 3 (MEKK3) phosphatase to inhibit lysophosphatidic acid-induced IkappaB kinase beta/nuclear factor-kappaB activation.
Sun W, Wang H, Zhao X, Yu Y, Fan Y, Wang H, Wang X, Lu X, Zhang G, Fu S, Yang J
The Journal of biological chemistry 2010 Jul 9;285(28):21341-8
The Journal of biological chemistry 2010 Jul 9;285(28):21341-8
Downregulation of active IKK beta by Ro52-mediated autophagy.
Niida M, Tanaka M, Kamitani T
Molecular immunology 2010 Aug;47(14):2378-87
Molecular immunology 2010 Aug;47(14):2378-87
Role of Src signal transduction pathways in scatter factor-mediated cellular protection.
Fan S, Meng Q, Laterra JJ, Rosen EM
The Journal of biological chemistry 2009 Mar 20;284(12):7561-77
The Journal of biological chemistry 2009 Mar 20;284(12):7561-77
Negative feedback loop in T cell activation through IkappaB kinase-induced phosphorylation and degradation of Bcl10.
Lobry C, Lopez T, Israël A, Weil R
Proceedings of the National Academy of Sciences of the United States of America 2007 Jan 16;104(3):908-13
Proceedings of the National Academy of Sciences of the United States of America 2007 Jan 16;104(3):908-13
Iron-mediated H2O2 production as a mechanism for cell type-specific inhibition of tumor necrosis factor alpha-induced but not interleukin-1beta-induced IkappaB kinase complex/nuclear factor-kappaB activation.
Panopoulos A, Harraz M, Engelhardt JF, Zandi E
The Journal of biological chemistry 2005 Jan 28;280(4):2912-23
The Journal of biological chemistry 2005 Jan 28;280(4):2912-23
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