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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations [0]
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- Product number
- ABIN966374 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) (pSer474) antibody
- Antibody type
- Polyclonal
- Antigen
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to middle amino acid residues of human IKBKB (Inhibitor of nuclear factor kappa-B kinase subunit beta)
- Reactivity
- Human
- Epitope
- pSer474
- Vial size
- 0.1 mg
Submitted references PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages.
Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases.
Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase.
The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation.
Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation.
Assignment of IkappaB kinase beta (IKBKB) to human chromosome band 8p12-->p11 by in situ hybridization.
IKAP is a scaffold protein of the IkappaB kinase complex.
IkappaB kinase-alpha and -beta genes are coexpressed in adult and embryonic tissues but localized to different human chromosomes.
Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase.
IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK.
IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation.
Bruey JM, Bruey-Sedano N, Newman R, Chandler S, Stehlik C, Reed JC
The Journal of biological chemistry 2004 Dec 10;279(50):51897-907
The Journal of biological chemistry 2004 Dec 10;279(50):51897-907
Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases.
Chariot A, Leonardi A, Muller J, Bonif M, Brown K, Siebenlist U
The Journal of biological chemistry 2002 Oct 4;277(40):37029-36
The Journal of biological chemistry 2002 Oct 4;277(40):37029-36
Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase.
Wu RC, Qin J, Hashimoto Y, Wong J, Xu J, Tsai SY, Tsai MJ, O'Malley BW
Molecular and cellular biology 2002 May;22(10):3549-61
Molecular and cellular biology 2002 May;22(10):3549-61
The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation.
Sanz L, Sanchez P, Lallena MJ, Diaz-Meco MT, Moscat J
The EMBO journal 1999 Jun 1;18(11):3044-53
The EMBO journal 1999 Jun 1;18(11):3044-53
Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation.
Delhase M, Hayakawa M, Chen Y, Karin M
Science (New York, N.Y.) 1999 Apr 9;284(5412):309-13
Science (New York, N.Y.) 1999 Apr 9;284(5412):309-13
Assignment of IkappaB kinase beta (IKBKB) to human chromosome band 8p12-->p11 by in situ hybridization.
Shindo M, Nakano H, Sakon S, Yagita H, Mihara M, Okumura K
Cytogenetics and cell genetics 1998;82(1-2):32-3
Cytogenetics and cell genetics 1998;82(1-2):32-3
IKAP is a scaffold protein of the IkappaB kinase complex.
Cohen L, Henzel WJ, Baeuerle PA
Nature 1998 Sep 17;395(6699):292-6
Nature 1998 Sep 17;395(6699):292-6
IkappaB kinase-alpha and -beta genes are coexpressed in adult and embryonic tissues but localized to different human chromosomes.
Hu MC, Wang Y
Gene 1998 Nov 5;222(1):31-40
Gene 1998 Nov 5;222(1):31-40
Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase.
Nemoto S, DiDonato JA, Lin A
Molecular and cellular biology 1998 Dec;18(12):7336-43
Molecular and cellular biology 1998 Dec;18(12):7336-43
IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK.
Woronicz JD, Gao X, Cao Z, Rothe M, Goeddel DV
Science (New York, N.Y.) 1997 Oct 31;278(5339):866-9
Science (New York, N.Y.) 1997 Oct 31;278(5339):866-9
IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation.
Mercurio F, Zhu H, Murray BW, Shevchenko A, Bennett BL, Li J, Young DB, Barbosa M, Mann M, Manning A, Rao A
Science (New York, N.Y.) 1997 Oct 31;278(5339):860-6
Science (New York, N.Y.) 1997 Oct 31;278(5339):860-6
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