ABIN966377

antibody from antibodies-online

Targeting: IKBKB IKK-beta, IKK2, IKKB, NFKBIKB

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN966377

Provider

antibodies-online

Product name

anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) (C-Term), (pSer740) antibody

Antibody type

Polyclonal

Antigen

Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to very C-terminal residues of human IKBKB (Inhibitor of nuclear factor kappa-B kinase subunit beta)

Reactivity

Human

Epitope

C-Term,pSer740

Vial size

0.1 mg

References

Submitted references

PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages.

Bruey JM, Bruey-Sedano N, Newman R, Chandler S, Stehlik C, Reed JC
The Journal of biological chemistry 2004 Dec 10;279(50):51897-907

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Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases.

Chariot A, Leonardi A, Muller J, Bonif M, Brown K, Siebenlist U
The Journal of biological chemistry 2002 Oct 4;277(40):37029-36

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Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase.

Wu RC, Qin J, Hashimoto Y, Wong J, Xu J, Tsai SY, Tsai MJ, O'Malley BW
Molecular and cellular biology 2002 May;22(10):3549-61

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The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation.

Sanz L, Sanchez P, Lallena MJ, Diaz-Meco MT, Moscat J
The EMBO journal 1999 Jun 1;18(11):3044-53

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Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation.

Delhase M, Hayakawa M, Chen Y, Karin M
Science (New York, N.Y.) 1999 Apr 9;284(5412):309-13

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Assignment of IkappaB kinase beta (IKBKB) to human chromosome band 8p12-->p11 by in situ hybridization.

Shindo M, Nakano H, Sakon S, Yagita H, Mihara M, Okumura K
Cytogenetics and cell genetics 1998;82(1-2):32-3

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IKAP is a scaffold protein of the IkappaB kinase complex.

Cohen L, Henzel WJ, Baeuerle PA
Nature 1998 Sep 17;395(6699):292-6

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IkappaB kinase-alpha and -beta genes are coexpressed in adult and embryonic tissues but localized to different human chromosomes.

Hu MC, Wang Y
Gene 1998 Nov 5;222(1):31-40

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Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase.

Nemoto S, DiDonato JA, Lin A
Molecular and cellular biology 1998 Dec;18(12):7336-43

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IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK.

Woronicz JD, Gao X, Cao Z, Rothe M, Goeddel DV
Science (New York, N.Y.) 1997 Oct 31;278(5339):866-9

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IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation.

Mercurio F, Zhu H, Murray BW, Shevchenko A, Bennett BL, Li J, Young DB, Barbosa M, Mann M, Manning A, Rao A
Science (New York, N.Y.) 1997 Oct 31;278(5339):860-6