Explore
Validate
Learn
Western blot
ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN967355 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) antibody
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Purified from tissue culture supernatant or ascites by affinity chromatography.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- F18-1875
- Vial size
- 50 μg
- Storage
- -20°C
Submitted references The IKK complex: an integrator of all signals that activate NF-kappaB?
The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis.
JNK2 and IKKbeta are required for activating the innate response to viral infection.
Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice.
Severe liver degeneration in mice lacking the IkappaB kinase 2 gene.
IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex.
NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176.
Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1.
IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation.
Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway.
MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1.
A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB.
Israël A
Trends in cell biology 2000 Apr;10(4):129-33
Trends in cell biology 2000 Apr;10(4):129-33
The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis.
Li ZW, Chu W, Hu Y, Delhase M, Deerinck T, Ellisman M, Johnson R, Karin M
The Journal of experimental medicine 1999 Jun 7;189(11):1839-45
The Journal of experimental medicine 1999 Jun 7;189(11):1839-45
JNK2 and IKKbeta are required for activating the innate response to viral infection.
Chu WM, Ostertag D, Li ZW, Chang L, Chen Y, Hu Y, Williams B, Perrault J, Karin M
Immunity 1999 Dec;11(6):721-31
Immunity 1999 Dec;11(6):721-31
Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice.
Tanaka M, Fuentes ME, Yamaguchi K, Durnin MH, Dalrymple SA, Hardy KL, Goeddel DV
Immunity 1999 Apr;10(4):421-9
Immunity 1999 Apr;10(4):421-9
Severe liver degeneration in mice lacking the IkappaB kinase 2 gene.
Li Q, Van Antwerp D, Mercurio F, Lee KF, Verma IM
Science (New York, N.Y.) 1999 Apr 9;284(5412):321-5
Science (New York, N.Y.) 1999 Apr 9;284(5412):321-5
IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex.
Rothwarf DM, Zandi E, Natoli G, Karin M
Nature 1998 Sep 17;395(6699):297-300
Nature 1998 Sep 17;395(6699):297-300
NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176.
Ling L, Cao Z, Goeddel DV
Proceedings of the National Academy of Sciences of the United States of America 1998 Mar 31;95(7):3792-7
Proceedings of the National Academy of Sciences of the United States of America 1998 Mar 31;95(7):3792-7
Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1.
Nakano H, Shindo M, Sakon S, Nishinaka S, Mihara M, Yagita H, Okumura K
Proceedings of the National Academy of Sciences of the United States of America 1998 Mar 31;95(7):3537-42
Proceedings of the National Academy of Sciences of the United States of America 1998 Mar 31;95(7):3537-42
IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation.
Mercurio F, Zhu H, Murray BW, Shevchenko A, Bennett BL, Li J, Young DB, Barbosa M, Mann M, Manning A, Rao A
Science (New York, N.Y.) 1997 Oct 31;278(5339):860-6
Science (New York, N.Y.) 1997 Oct 31;278(5339):860-6
Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway.
Lee FS, Hagler J, Chen ZJ, Maniatis T
Cell 1997 Jan 24;88(2):213-22
Cell 1997 Jan 24;88(2):213-22
MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1.
Malinin NL, Boldin MP, Kovalenko AV, Wallach D
Nature 1997 Feb 6;385(6616):540-4
Nature 1997 Feb 6;385(6616):540-4
A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB.
DiDonato JA, Hayakawa M, Rothwarf DM, Zandi E, Karin M
Nature 1997 Aug 7;388(6642):548-54
Nature 1997 Aug 7;388(6642):548-54
No comments: Submit comment
No validations: Submit validation data