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antibody from Invitrogen Antibodies
Targeting: IL1RN
ICIL-1RA, IL-1RN, IL1F3, IL1RA, IRAP, MGC10430
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Flow cytometry [1]
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- Product number
- 11-7015-82 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- IL1RA Monoclonal Antibody (CRM17), FITC, eBioscience™
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Description: The CRM17 antibody reacts with human interleukin-1 receptor antagonist (IL-1RA). IL-1RA is produced by macrophages, monocytes, neutrophils, synovial and dermal fibroblasts. The 17 kDa soluble form of IL-1RA (sIL-1RA) is produced by hepatocytes. IL-1RA inhibits the release of both forms of IL-1, the secretion of IL-2, and the expression of IL-2 receptors on the cell surface. IL-1RA also blocks the stimulation of prostaglandin E2 synthesis in synovial cells and the proliferation of thymocytes.
- Conjugate
- Green dye
- Antibody clone number
- CRM17
- Concentration
- 0.5 mg/mL
Submitted references Difference in cytokine production and cell cycle progression induced by Epstein-Barr virus Lmp1 deletion variants in Kmh2, a Hodgkin lymphoma cell line.
Sueur C, Lupo J, Mas P, Morand P, Boyer V
Virology journal 2014 May 19;11:94
Virology journal 2014 May 19;11:94
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Normal human peripheral blood cells were stimulated with LPS in the presence of Brefeldin A (Product # 00-4506-51) for 24 hours. The cells were surface stained with Anti-Human CD14 PE (Product # 12-0149-42) and intracellularly stained with Mouse IgG1 K Isotype Control FITC (Product # 11-4714-42) (left) or Anti-Human IL-1 Receptor Antagonist FITC (right).
- Conjugate
- Green dye
