HLCS

Holocarboxylase synthetase

HCS

This gene encodes an enzyme that catalyzes the binding of biotin to carboxylases and histones. The protein plays an important role in gluconeogenesis, fatty acid synthesis and branched chain amino acid catabolism. Defects in this gene are the cause of holocarboxylase synthetase deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jun 2011]

Ensembl	UniProt	RefSeq	Entrez
ENST00000336648 ENSP00000338387	P50747.192 P50747	NP_001339444.1 NP_001339444 NP_000402.3 NP_000402	HLCS 3141
ENST00000399120 ENSP00000382071	P50747.192 P50747		HLCS 3141
ENST00000427746 ENSP00000396443	C9JCQ9		HLCS 3141
ENST00000448340 ENSP00000392923	A0A0C4DG27		HLCS 3141
ENST00000612277 ENSP00000479939	P50747.192 P50747	NP_001339446.1 NP_001339446 NP_001229714.1 NP_001229714	HLCS 3141
ENST00000674895 ENSP00000502087		NP_001229713.1 NP_001229713 NP_001339447.1 NP_001339447 NP_001339443.1 NP_001339443	HLCS 3141
ENST00000675307 ENSP00000501750		NP_001339445.1 NP_001339445	HLCS 3141

Ensembl	UniProt	RefSeq	Entrez
ENSMUST00000099512 ENSMUSP00000097112	Q920N2.137 Q920N2 Q3TZ03		Hlcs 110948
ENSMUST00000163193 ENSMUSP00000130981	Q920N2.137 Q920N2 Q3TZ03	NP_631884.1 NP_631884	Hlcs 110948
ENSMUST00000227141 ENSMUSP00000153773	A0A2I3BPG4	NP_001346974.1 NP_001346974	Hlcs 110948
ENSMUST00000227698 ENSMUSP00000154056	A0A2I3BQG1		Hlcs 110948
ENSMUST00000228910 ENSMUSP00000154157	Q3TG10		Hlcs 110948

More gene data

Top validated antibodies
Novus Biologicals	NBP1-81759	1 references	Polyclonal	WB ICC IHC
antibodies-online	ABIN2716652		Monoclonal	WB IHC FC
Invitrogen Antibodies	CF504422		Monoclonal	WB IHC FC
OriGene	TA504422		Monoclonal	WB IHC FC
Proteintech Group	14046-1-AP		Polyclonal	WB EL ICC

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153 antibodies from 22 providers.

Show Additional Columns

	Antibody	Refs	Type
Novus Biologicals 35 antibodies
	NBP1-81759	1	Polyclonal
	NBP2-01859		Monoclonal

Invitrogen Antibodies 10 antibodies
	CF504422		Monoclonal
	TA504422		Monoclonal

antibodies-online 33 antibodies
	ABIN2716652		Monoclonal
	ABIN4319287		Monoclonal

OriGene 3 antibodies
	TA504422		Monoclonal
	CF504422		Monoclonal

Proteintech Group 1 antibody
	14046-1-AP		Polyclonal

NovoPro Bioscience Inc. 1 antibody
	111432		Polyclonal

Abnova Corporation 6 antibodies
	H00003141-D01		Polyclonal
	H00003141-B01P		Polyclonal

Atlas Antibodies 1 antibody
	HPA017379		Polyclonal

GeneTex 1 antibody
	GTX109815		Polyclonal

LSBio 25 antibodies
	LS-C173805		Monoclonal
	LS-C786979		Monoclonal

Cusabio Biotech Co., Ltd 5 antibodies
	CSB-PA010518GA01HU		Polyclonal
	CSB-PA010518LA01HU		Polyclonal

Bethyl Laboratories 1 antibody
	A304-261A		Polyclonal

Wuhan Fine Biotech Co., Ltd. 1 antibody
	FNab03913		Polyclonal

Aviva Systems Biology 1 antibody
	ARP74943_P050		Polyclonal

Molecular Depot LLC 1 antibody
	A2010021		Monoclonal

RabMAbs 1 antibody
	ab137126		Monoclonal

MyBioSource 3 antibodies
	MBS271414		Polyclonal
	MBS710791		Polyclonal

Creative Biolabs 7 antibodies
	MOB-2416z-S(P)		Monoclonal
	MOB-2416z-F(E)		Monoclonal

Creative Diagnostics 3 antibodies
	DPABH-15071		Polyclonal
	CABT-B1277		Monoclonal

MilliporeSigma / Merck KGaA 1 antibody
	HPA017379		Polyclonal

United States Biological 12 antibodies
	211291		Polyclonal
	211291-AP		Polyclonal

Abbexa 1 antibody
	abx113044		Polyclonal

HLCS

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HLCS

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