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- Product number
- ABIN152077 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Rabbit
- Vial size
- 0.1 mL
- Storage
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Radiation-induced lung metastasis development is MT1-MMP-dependent in a triple-negative breast cancer mouse model.
Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment, prognosis, and invasive potential.
Baseline [(18)F]FMISO μPET as a Predictive Biomarker for Response to HIF-1α Inhibition Combined with 5-FU Chemotherapy in a Human Colorectal Cancer Xenograft Model.
Hypoxia simultaneously alters satellite cell-mediated angiogenesis and hepatocyte growth factor expression.
Tumor cells upregulate normoxic HIF-1α in response to doxorubicin.
Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in a HIF-dependent manner.
Retinal neuroprotection by hypoxic preconditioning is independent of hypoxia-inducible factor-1 alpha expression in photoreceptors.
Inhibition of HIF-1alpha by the anticancer drug TAS106 enhances X-ray-induced apoptosis in vitro and in vivo.
Hypoxia-inducible factor-1 (HIF-1) is involved in the regulation of hypoxia-stimulated expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) and MCP-5 (Ccl12) in astrocytes.
Bouchard G, Therriault H, Geha S, Bujold R, Saucier C, Paquette B
British journal of cancer 2017 Feb 14;116(4):479-488
British journal of cancer 2017 Feb 14;116(4):479-488
Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment, prognosis, and invasive potential.
Knudsen ES, Balaji U, Freinkman E, McCue P, Witkiewicz AK
Oncotarget 2016 Nov 29;7(48):78396-78411
Oncotarget 2016 Nov 29;7(48):78396-78411
Baseline [(18)F]FMISO μPET as a Predictive Biomarker for Response to HIF-1α Inhibition Combined with 5-FU Chemotherapy in a Human Colorectal Cancer Xenograft Model.
De Bruycker S, Vangestel C, Van den Wyngaert T, Wyffels L, Wouters A, Pauwels P, Staelens S, Stroobants S
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2016 Aug;18(4):606-16
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2016 Aug;18(4):606-16
Hypoxia simultaneously alters satellite cell-mediated angiogenesis and hepatocyte growth factor expression.
Flann KL, Rathbone CR, Cole LC, Liu X, Allen RE, Rhoads RP
Journal of cellular physiology 2014 May;229(5):572-9
Journal of cellular physiology 2014 May;229(5):572-9
Tumor cells upregulate normoxic HIF-1α in response to doxorubicin.
Cao Y, Eble JM, Moon E, Yuan H, Weitzel DH, Landon CD, Nien CY, Hanna G, Rich JN, Provenzale JM, Dewhirst MW
Cancer research 2013 Oct 15;73(20):6230-42
Cancer research 2013 Oct 15;73(20):6230-42
Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in a HIF-dependent manner.
Chiang CK, Tanaka T, Inagi R, Fujita T, Nangaku M
Laboratory investigation; a journal of technical methods and pathology 2011 Nov;91(11):1564-71
Laboratory investigation; a journal of technical methods and pathology 2011 Nov;91(11):1564-71
Retinal neuroprotection by hypoxic preconditioning is independent of hypoxia-inducible factor-1 alpha expression in photoreceptors.
Thiersch M, Lange C, Joly S, Heynen S, Le YZ, Samardzija M, Grimm C
The European journal of neuroscience 2009 Jun;29(12):2291-302
The European journal of neuroscience 2009 Jun;29(12):2291-302
Inhibition of HIF-1alpha by the anticancer drug TAS106 enhances X-ray-induced apoptosis in vitro and in vivo.
Yasui H, Ogura A, Asanuma T, Matsuda A, Kashiwakura I, Kuwabara M, Inanami O
British journal of cancer 2008 Nov 4;99(9):1442-52
British journal of cancer 2008 Nov 4;99(9):1442-52
Hypoxia-inducible factor-1 (HIF-1) is involved in the regulation of hypoxia-stimulated expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) and MCP-5 (Ccl12) in astrocytes.
Mojsilovic-Petrovic J, Callaghan D, Cui H, Dean C, Stanimirovic DB, Zhang W
Journal of neuroinflammation 2007 May 2;4:12
Journal of neuroinflammation 2007 May 2;4:12
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