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HIF1A
Hypoxia inducible factor 1 subunit alphabHLHe78, HIF-1alpha, HIF1, MOP1, PASD8
This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]
Top validated antibodies |
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| Novus Biologicals |  NB100-105 |
852 references | Monoclonal |
WB
EL
ICC
IP
IHC
FC
GS
PLA
ChIP
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| GeneTex | GTX30105 |
6 references | Monoclonal |
WB
EL
ICC
IP
IHC
FC
GS
ChIP
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| Proteintech Group | 20960-1-AP |
573 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| Invitrogen Antibodies | PA3-16521 |
4 references | Polyclonal |
WB
EL
ICC
IP
IHC
GS
ChIP
OA
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| antibodies-online | ABIN151033 |
688 references | Monoclonal |
WB
EL
ICC
IP
IHC
FC
GS
ChIP
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