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- References [22]
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- Product number
- ABIN249572 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) antibody (HRP)
- Antibody type
- Monoclonal
- Description
- Protein G purified
- Reactivity
- Human, Mouse, Rat, Bovine, Porcine, Rabbit, Sheep, Simian, Xenopus, Yeast
- Host
- Mouse
- Conjugate
- Horseradish Peroxidase
- Isotype
- IgG
- Antibody clone number
- H1alpha67
- Vial size
- 0.1 mL
- Storage
- Store at 4°C in the dark.
Submitted references A possible role for hypoxia-induced apelin expression in enteric cell proliferation.
Involvement of hypoxia-inducible transcription factors in polycystic kidney disease.
Hypoxia-inducible factor 1alpha stabilization by carbon monoxide results in cytoprotective preconditioning.
Myocardial hypoxia-inducible HIF-1alpha, VEGF, and GLUT1 gene expression is associated with microvascular and ICAM-1 heterogeneity during endotoxemia.
Characterization of cell clones isolated from hypoxia-selected renal proximal tubular cells.
Cell type-specific, topoisomerase II-dependent inhibition of hypoxia-inducible factor-1alpha protein accumulation by NSC 644221.
Hypoxic stress induces dimethylated histone H3 lysine 9 through histone methyltransferase G9a in mammalian cells.
The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes.
Latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells activates hypoxia-induced factors.
Histone deacetylase inhibitors repress the transactivation potential of hypoxia-inducible factors independently of direct acetylation of HIF-alpha.
Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure.
Essential role of B-Raf in ERK activation during extraembryonic development.
Simvastatin promotes angiogenesis and prevents microvascular remodeling in chronic renal ischemia.
Improved lung growth and function through hypoxia-inducible factor in primate chronic lung disease of prematurity.
Cell-specific regulation of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha stabilization and transactivation in a graded oxygen environment.
Targeted anti-vascular endothelial growth factor receptor-2 therapy leads to short-term and long-term impairment of vascular function and increase in tumor hypoxia.
Prosurvival and prodeath effects of hypoxia-inducible factor-1alpha stabilization in a murine hippocampal cell line.
Loss of the von Hippel Lindau tumor suppressor disrupts iron homeostasis in renal carcinoma cells.
Expression of hypoxia-inducible factor 1alpha in epithelial ovarian tumors: its impact on prognosis and on response to chemotherapy.
Expression of hypoxia-inducible factor-1 alpha in oligodendrogliomas: its impact on prognosis and on neoangiogenesis.
Induction of vascular endothelial growth factor expression and hypoxia-inducible factor 1alpha protein by the oxidative stressor arsenite.
Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer.
Han S, Wang G, Qi X, Lee HM, Englander EW, Greeley GH Jr
American journal of physiology. Regulatory, integrative and comparative physiology 2008 Jun;294(6):R1832-9
American journal of physiology. Regulatory, integrative and comparative physiology 2008 Jun;294(6):R1832-9
Involvement of hypoxia-inducible transcription factors in polycystic kidney disease.
Bernhardt WM, Wiesener MS, Weidemann A, Schmitt R, Weichert W, Lechler P, Campean V, Ong AC, Willam C, Gretz N, Eckardt KU
The American journal of pathology 2007 Mar;170(3):830-42
The American journal of pathology 2007 Mar;170(3):830-42
Hypoxia-inducible factor 1alpha stabilization by carbon monoxide results in cytoprotective preconditioning.
Chin BY, Jiang G, Wegiel B, Wang HJ, Macdonald T, Zhang XC, Gallo D, Cszimadia E, Bach FH, Lee PJ, Otterbein LE
Proceedings of the National Academy of Sciences of the United States of America 2007 Mar 20;104(12):5109-14
Proceedings of the National Academy of Sciences of the United States of America 2007 Mar 20;104(12):5109-14
Myocardial hypoxia-inducible HIF-1alpha, VEGF, and GLUT1 gene expression is associated with microvascular and ICAM-1 heterogeneity during endotoxemia.
Bateman RM, Tokunaga C, Kareco T, Dorscheid DR, Walley KR
American journal of physiology. Heart and circulatory physiology 2007 Jul;293(1):H448-56
American journal of physiology. Heart and circulatory physiology 2007 Jul;293(1):H448-56
Characterization of cell clones isolated from hypoxia-selected renal proximal tubular cells.
Brooks C, Wang J, Yang T, Dong Z
American journal of physiology. Renal physiology 2007 Jan;292(1):F243-52
American journal of physiology. Renal physiology 2007 Jan;292(1):F243-52
Cell type-specific, topoisomerase II-dependent inhibition of hypoxia-inducible factor-1alpha protein accumulation by NSC 644221.
Creighton-Gutteridge M, Cardellina JH 2nd, Stephen AG, Rapisarda A, Uranchimeg B, Hite K, Denny WA, Shoemaker RH, Melillo G
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Feb 1;13(3):1010-8
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Feb 1;13(3):1010-8
Hypoxic stress induces dimethylated histone H3 lysine 9 through histone methyltransferase G9a in mammalian cells.
Chen H, Yan Y, Davidson TL, Shinkai Y, Costa M
Cancer research 2006 Sep 15;66(18):9009-16
Cancer research 2006 Sep 15;66(18):9009-16
The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes.
Chavez JC, Baranova O, Lin J, Pichiule P
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 Sep 13;26(37):9471-81
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 Sep 13;26(37):9471-81
Latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells activates hypoxia-induced factors.
Carroll PA, Kenerson HL, Yeung RS, Lagunoff M
Journal of virology 2006 Nov;80(21):10802-12
Journal of virology 2006 Nov;80(21):10802-12
Histone deacetylase inhibitors repress the transactivation potential of hypoxia-inducible factors independently of direct acetylation of HIF-alpha.
Fath DM, Kong X, Liang D, Lin Z, Chou A, Jiang Y, Fang J, Caro J, Sang N
The Journal of biological chemistry 2006 May 12;281(19):13612-9
The Journal of biological chemistry 2006 May 12;281(19):13612-9
Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure.
Bernhardt WM, Câmpean V, Kany S, Jürgensen JS, Weidemann A, Warnecke C, Arend M, Klaus S, Günzler V, Amann K, Willam C, Wiesener MS, Eckardt KU
Journal of the American Society of Nephrology : JASN 2006 Jul;17(7):1970-8
Journal of the American Society of Nephrology : JASN 2006 Jul;17(7):1970-8
Essential role of B-Raf in ERK activation during extraembryonic development.
Galabova-Kovacs G, Matzen D, Piazzolla D, Meissl K, Plyushch T, Chen AP, Silva A, Baccarini M
Proceedings of the National Academy of Sciences of the United States of America 2006 Jan 31;103(5):1325-30
Proceedings of the National Academy of Sciences of the United States of America 2006 Jan 31;103(5):1325-30
Simvastatin promotes angiogenesis and prevents microvascular remodeling in chronic renal ischemia.
Chade AR, Zhu X, Mushin OP, Napoli C, Lerman A, Lerman LO
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006 Aug;20(10):1706-8
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006 Aug;20(10):1706-8
Improved lung growth and function through hypoxia-inducible factor in primate chronic lung disease of prematurity.
Asikainen TM, Chang LY, Coalson JJ, Schneider BK, Waleh NS, Ikegami M, Shannon JM, Winter VT, Grubb P, Clyman RI, Yoder BA, Crapo JD, White CW
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006 Aug;20(10):1698-700
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006 Aug;20(10):1698-700
Cell-specific regulation of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha stabilization and transactivation in a graded oxygen environment.
Bracken CP, Fedele AO, Linke S, Balrak W, Lisy K, Whitelaw ML, Peet DJ
The Journal of biological chemistry 2006 Aug 11;281(32):22575-85
The Journal of biological chemistry 2006 Aug 11;281(32):22575-85
Targeted anti-vascular endothelial growth factor receptor-2 therapy leads to short-term and long-term impairment of vascular function and increase in tumor hypoxia.
Franco M, Man S, Chen L, Emmenegger U, Shaked Y, Cheung AM, Brown AS, Hicklin DJ, Foster FS, Kerbel RS
Cancer research 2006 Apr 1;66(7):3639-48
Cancer research 2006 Apr 1;66(7):3639-48
Prosurvival and prodeath effects of hypoxia-inducible factor-1alpha stabilization in a murine hippocampal cell line.
Aminova LR, Chavez JC, Lee J, Ryu H, Kung A, Lamanna JC, Ratan RR
The Journal of biological chemistry 2005 Feb 4;280(5):3996-4003
The Journal of biological chemistry 2005 Feb 4;280(5):3996-4003
Loss of the von Hippel Lindau tumor suppressor disrupts iron homeostasis in renal carcinoma cells.
Alberghini A, Recalcati S, Tacchini L, Santambrogio P, Campanella A, Cairo G
The Journal of biological chemistry 2005 Aug 26;280(34):30120-8
The Journal of biological chemistry 2005 Aug 26;280(34):30120-8
Expression of hypoxia-inducible factor 1alpha in epithelial ovarian tumors: its impact on prognosis and on response to chemotherapy.
Birner P, Schindl M, Obermair A, Breitenecker G, Oberhuber G
Clinical cancer research : an official journal of the American Association for Cancer Research 2001 Jun;7(6):1661-8
Clinical cancer research : an official journal of the American Association for Cancer Research 2001 Jun;7(6):1661-8
Expression of hypoxia-inducible factor-1 alpha in oligodendrogliomas: its impact on prognosis and on neoangiogenesis.
Birner P, Gatterbauer B, Oberhuber G, Schindl M, Rössler K, Prodinger A, Budka H, Hainfellner JA
Cancer 2001 Jul 1;92(1):165-71
Cancer 2001 Jul 1;92(1):165-71
Induction of vascular endothelial growth factor expression and hypoxia-inducible factor 1alpha protein by the oxidative stressor arsenite.
Duyndam MC, Hulscher TM, Fontijn D, Pinedo HM, Boven E
The Journal of biological chemistry 2001 Dec 21;276(51):48066-76
The Journal of biological chemistry 2001 Dec 21;276(51):48066-76
Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer.
Birner P, Schindl M, Obermair A, Plank C, Breitenecker G, Oberhuber G
Cancer research 2000 Sep 1;60(17):4693-6
Cancer research 2000 Sep 1;60(17):4693-6
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Supportive validation
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