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- Antigen structure
- References [7]
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- Validations
- Western blot [1]
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- Product number
- PAB12138 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12138, RRID:AB_10554024
- Product name
- Hif1a polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against partial recombinant Hif1a.
- Storage
- Store at 4°C. Do not freeze.
Submitted references Hypoxia Signaling Cascade for Erythropoietin Production in Hepatocytes.
Oxidized low-density lipoprotein stimulates macrophage 18F-FDG uptake via hypoxia-inducible factor-1α activation through Nox2-dependent reactive oxygen species generation.
High oxygen prevents fetal lethality due to lack of catecholamines.
HIF1alpha is essential for normal intrauterine differentiation of alveolar epithelium and surfactant production in the newborn lung of mice.
Impaired DNA double-strand break repair contributes to chemoresistance in HIF-1 alpha-deficient mouse embryonic fibroblasts.
Increased expression of HIF-1alpha, nNOS, and VEGF in the cerebral cortex of anemic rats.
Hypoxia-inducible factor-1alpha is a key regulator of metastasis in a transgenic model of cancer initiation and progression.
Tojo Y, Sekine H, Hirano I, Pan X, Souma T, Tsujita T, Kawaguchi S, Takeda N, Takeda K, Fong GH, Dan T, Ichinose M, Miyata T, Yamamoto M, Suzuki N
Molecular and cellular biology 2015 Aug;35(15):2658-72
Molecular and cellular biology 2015 Aug;35(15):2658-72
Oxidized low-density lipoprotein stimulates macrophage 18F-FDG uptake via hypoxia-inducible factor-1α activation through Nox2-dependent reactive oxygen species generation.
Lee SJ, Thien Quach CH, Jung KH, Paik JY, Lee JH, Park JW, Lee KH
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2014 Oct;55(10):1699-705
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2014 Oct;55(10):1699-705
High oxygen prevents fetal lethality due to lack of catecholamines.
Ream MA, Chandra R, Peavey M, Ray AM, Roffler-Tarlov S, Kim HG, Wetsel WC, Rockman HA, Chikaraishi DM
American journal of physiology. Regulatory, integrative and comparative physiology 2008 Sep;295(3):R942-53
American journal of physiology. Regulatory, integrative and comparative physiology 2008 Sep;295(3):R942-53
HIF1alpha is essential for normal intrauterine differentiation of alveolar epithelium and surfactant production in the newborn lung of mice.
Saini Y, Harkema JR, LaPres JJ
The Journal of biological chemistry 2008 Nov 28;283(48):33650-7
The Journal of biological chemistry 2008 Nov 28;283(48):33650-7
Impaired DNA double-strand break repair contributes to chemoresistance in HIF-1 alpha-deficient mouse embryonic fibroblasts.
Wirthner R, Wrann S, Balamurugan K, Wenger RH, Stiehl DP
Carcinogenesis 2008 Dec;29(12):2306-16
Carcinogenesis 2008 Dec;29(12):2306-16
Increased expression of HIF-1alpha, nNOS, and VEGF in the cerebral cortex of anemic rats.
McLaren AT, Marsden PA, Mazer CD, Baker AJ, Stewart DJ, Tsui AK, Li X, Yucel Y, Robb M, Boyd SR, Liu E, Yu J, Hare GM
American journal of physiology. Regulatory, integrative and comparative physiology 2007 Jan;292(1):R403-14
American journal of physiology. Regulatory, integrative and comparative physiology 2007 Jan;292(1):R403-14
Hypoxia-inducible factor-1alpha is a key regulator of metastasis in a transgenic model of cancer initiation and progression.
Liao D, Corle C, Seagroves TN, Johnson RS
Cancer research 2007 Jan 15;67(2):563-72
Cancer research 2007 Jan 15;67(2):563-72
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Supportive validation
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- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of Hif1a in a hypoxic sample using Hif1a polyclonal antibody (Cat # PAB12138). Lane 1 : CoCl2 treated COS-7 nuclear extract (50 ug, hypoxic). Lane 2 : Untreated COS-7 nuclear extract (50 ug, normoxic). 10 second ECL exposure.
