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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- ABIN152188 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) antibody
- Antibody type
- Monoclonal
- Antigen
- NB 100-131: Human HIF-1 alpha amino acids 329-530.NB100-123: Fusion protein containing amino acids 432-528 of human HIF-1alpha.NB100-449: peptide between residues 775 and the C-terminus (residue 826) of humanHIF-1 alpha.ABIN151926: A fusion protein including residues 530-825 of the mouse HIF-1 alphaprotein.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 4 vials
- Storage
- Store at 4C. Do not freeze.
Submitted references Inhibition of hypoxia inducible factor hydroxylases protects against renal ischemia-reperfusion injury.
Nitric oxide is a factor in the stabilization of hypoxia-inducible factor-1alpha in cancer: role of free radical formation.
Energy restriction lowers the expression of genes linked to inflammation, the cytoskeleton, the extracellular matrix, and angiogenesis in mouse adipose tissue.
Hypoxia-inducible factor modulates tubular cell survival in cisplatin nephrotoxicity.
Hill P, Shukla D, Tran MG, Aragones J, Cook HT, Carmeliet P, Maxwell PH
Journal of the American Society of Nephrology : JASN 2008 Jan;19(1):39-46
Journal of the American Society of Nephrology : JASN 2008 Jan;19(1):39-46
Nitric oxide is a factor in the stabilization of hypoxia-inducible factor-1alpha in cancer: role of free radical formation.
Quintero M, Brennan PA, Thomas GJ, Moncada S
Cancer research 2006 Jan 15;66(2):770-4
Cancer research 2006 Jan 15;66(2):770-4
Energy restriction lowers the expression of genes linked to inflammation, the cytoskeleton, the extracellular matrix, and angiogenesis in mouse adipose tissue.
Higami Y, Barger JL, Page GP, Allison DB, Smith SR, Prolla TA, Weindruch R
The Journal of nutrition 2006 Feb;136(2):343-52
The Journal of nutrition 2006 Feb;136(2):343-52
Hypoxia-inducible factor modulates tubular cell survival in cisplatin nephrotoxicity.
Tanaka T, Kojima I, Ohse T, Inagi R, Miyata T, Ingelfinger JR, Fujita T, Nangaku M
American journal of physiology. Renal physiology 2005 Nov;289(5):F1123-33
American journal of physiology. Renal physiology 2005 Nov;289(5):F1123-33
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Detection of HIF-1 alpha (red dye) in a cell cytospin from a lavage of a murine skin pouch infected with Staph Aureus, using ABIN151061. Blue dye is DAPI nuclear staining. Photos courtesy of Susan Alexander and Hattie Gresham, PhD.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- HIF-1 Alpha staining in hypoxia-induced human placenta using ABIN151061.
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Negative control stain of human placenta (from sea level) using mouse IgG at 1:100. 4uM paraffin-embedded section.
