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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Flow cytometry [1]
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- Product number
- ABIN120355 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Notch 1 (NOTCH1) antibody (PE)
- Antibody type
- Monoclonal
- Antigen
- Synthetic peptide corresponding to cdc10-NCR region within mouse Notch1. Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
- Description
- Affinity Chromatography on Protein G
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Yellow dye
- Isotype
- IgG
- Antibody clone number
- mN1A
- Vial size
- 100 tests
- Concentration
- 0.1 mg/mL
- Storage
- Original vial: 1 year at 2-8°C. After reconstitution, aliquot and freeze stock solution at -20°C.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Zoledronic acid inhibits osteosarcoma growth in an orthotopic model.
Loss of CBP causes T cell lymphomagenesis in synergy with p27Kip1 insufficiency.
p65-NFkappaB synergizes with Notch to activate transcription by triggering cytoplasmic translocation of the nuclear receptor corepressor N-CoR.
Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1.
Evidence for a physical interaction between presenilin and Notch.
Dass CR, Choong PF
Molecular cancer therapeutics 2007 Dec;6(12 Pt 1):3263-70
Molecular cancer therapeutics 2007 Dec;6(12 Pt 1):3263-70
Loss of CBP causes T cell lymphomagenesis in synergy with p27Kip1 insufficiency.
Kang-Decker N, Tong C, Boussouar F, Baker DJ, Xu W, Leontovich AA, Taylor WR, Brindle PK, van Deursen JM
Cancer cell 2004 Feb;5(2):177-89
Cancer cell 2004 Feb;5(2):177-89
p65-NFkappaB synergizes with Notch to activate transcription by triggering cytoplasmic translocation of the nuclear receptor corepressor N-CoR.
Espinosa L, Santos S, Inglés-Esteve J, Muñoz-Canoves P, Bigas A
Journal of cell science 2002 Mar 15;115(Pt 6):1295-303
Journal of cell science 2002 Mar 15;115(Pt 6):1295-303
Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1.
Huppert SS, Le A, Schroeter EH, Mumm JS, Saxena MT, Milner LA, Kopan R
Nature 2000 Jun 22;405(6789):966-70
Nature 2000 Jun 22;405(6789):966-70
Evidence for a physical interaction between presenilin and Notch.
Ray WJ, Yao M, Nowotny P, Mumm J, Zhang W, Wu JY, Kopan R, Goate AM
Proceedings of the National Academy of Sciences of the United States of America 1999 Mar 16;96(6):3263-8
Proceedings of the National Academy of Sciences of the United States of America 1999 Mar 16;96(6):3263-8
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Staining of mouse thymus with Mouse anti NOTCH1-RPE (ABIN120355)
