Antibody data
- Antibody Data
- Antigen structure
- References [55]
- Comments [0]
- Validations
- Western blot [3]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 18933-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18933-1-AP, RRID:AB_10641999
- Product name
- BMP2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated BMP2 antibody (Cat. #18933-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A personalized biomimetic dual-drug delivery system via controlled release of PTH(1-34) and simvastatin for in situ osteoporotic bone regeneration.
Improving osseointegration and antimicrobial properties of titanium implants with black phosphorus nanosheets-hydroxyapatite composite coatings for vascularized bone regeneration.
Impaired autophagy activity-induced abnormal differentiation of bone marrow stem cells is related to adolescent idiopathic scoliosis osteopenia.
The Wnt/β-catenin signaling pathway inhibits osteoporosis by regulating the expression of TERT: an in vivo and in vitro study.
Calcium Phosphate Bone Cements Incorporated with Black Phosphorus Nanosheets Enhanced Osteogenesis.
Oleoylethanolamide alleviates hyperlipidaemia-mediated vascular calcification via attenuating mitochondrial DNA stress triggered autophagy-dependent ferroptosis by activating PPARα.
RGMa Participates in the Blood-Brain Barrier Dysfunction Through BMP/BMPR/YAP Signaling in Multiple Sclerosis.
CoCl(2) -simulated hypoxia potentiates the osteogenic differentiation of fibroblasts derived from tympanosclerosis by upregulating the expression of BMP-2.
Chronic Alcohol Reduces Bone Mass Through Inhibiting Proliferation and Promoting Aging of Endothelial Cells in Type-H Vessels.
Vestigial-Like 3 Plays an Important Role in Osteoblast Differentiation by Regulating the Expression of Osteogenic Transcription Factors and BMP Signaling.
Oxalate induces the ossification of RTECs by activating the JAK2/STAT3 signaling pathway and participates in the formation of kidney stones.
miR-122-5p targets GREM2 to protect against glucocorticoid-induced endothelial damage through the BMP signaling pathway.
Postnatal eye size in mice is controlled by SREBP2-mediated transcriptional repression of Lrp2 and Bmp2.
Role of Nox4 in High Calcium-Induced Renal Oxidative Stress Damage and Crystal Deposition.
Altered Expression of the Hedgehog Pathway Proteins BMP2, BMP4, SHH, and IHH Involved in Knee Cartilage Damage of Patients With Osteoarthritis and Kashin-Beck Disease.
Inhibition of c-Jun N-terminal kinase signaling promotes osteoblastic differentiation of periodontal ligament stem cells and induces regeneration of periodontal tissues.
IL-18-Mediated SLC7A5 Overexpression Enhances Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells via the c-MYC Pathway.
Metformin attenuates hyperlipidaemia-associated vascular calcification through anti-ferroptotic effects.
Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway.
Cigarette smoke induced neural tube defects by down-regulating noggin expression.
BMP2 induces hMSC osteogenesis and matrix remodeling.
Higher BMP Expression in Tendon Stem/Progenitor Cells Contributes to the Increased Heterotopic Ossification in Achilles Tendon With Aging.
The Role of Tantalum Nanoparticles in Bone Regeneration Involves the BMP2/Smad4/Runx2 Signaling Pathway.
Experimental study of expression profile and specific role of human microRNAs in regulating atrophic bone nonunion.
Schisandrin B regulates MC3T3-E1 subclone 14 cells proliferation and differentiation through BMP2-SMADs-RUNX2-SP7 signaling axis.
The role of WNT1 mutant variant (WNT1(c.677C>T) ) in osteogenesis imperfecta.
Osteoking improves OP rat by enhancing HSP90‑β expression.
Expression and distribution of bone morphogenetic protein 4 and its antagonist Noggin in the skin of Kazakh sheep (Ovis aries) with a white and brown coat color.
SHED-derived conditioned exosomes enhance the osteogenic differentiation of PDLSCs via Wnt and BMP signaling in vitro.
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ERα and Wnt/β‑catenin signaling pathways are involved in angelicin‑dependent promotion of osteogenesis.
Oviductus Ranae protein hydrolyzate prevents menopausal osteoporosis by regulating TGFβ/BMP2 signaling.
Mmu-miR-185 depletion promotes osteogenic differentiation and suppresses bone loss in osteoporosis through the Bgn-mediated BMP/Smad pathway.
Specific knockdown of WNT8b expression protects against phosphate-induced calcification in vascular smooth muscle cells by inhibiting the Wnt-β-catenin signaling pathway.
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Bacitracin promotes osteogenic differentiation of human bone marrow mesenchymal stem cells by stimulating the bone morphogenetic protein-2/Smad axis.
Negative pressure wound therapy promotes muscle-derived stem cell osteogenic differentiation through MAPK pathway.
Icariin attenuates titanium particle-induced inhibition of osteogenic differentiation and matrix mineralization via miR-21-5p.
Myricetin ameliorates glucocorticoid-induced osteoporosis through the ERK signaling pathway.
Targeted silencing of SOX2 by an artificial transcription factor showed antitumor effect in lung and esophageal squamous cell carcinoma.
Overexpression of colorectal cancer oncogene CHRDL2 predicts a poor prognosis.
Promotive effects of bone morphogenetic protein 2 on angiogenesis in hepatocarcinoma via multiple signal pathways.
Metformin alleviates vascular calcification induced by vitamin D3 plus nicotine in rats via the AMPK pathway.
A fucoidan from Nemacystus decipiens disrupts angiogenesis through targeting bone morphogenetic protein 4.
Dynamic cultivation with radial flow bioreactor enhances proliferation or differentiation of rat bone marrow cells by fibroblast growth factor or osteogenic differentiation factor.
Guided bone regeneration is promoted by the molecular events in the membrane compartment.
Hypoxia-induced MTA1 promotes MC3T3 osteoblast growth but suppresses MC3T3 osteoblast differentiation.
Overexpression of c1q/tumor necrosis factor-related protein-3 promotes phosphate-induced vascular smooth muscle cell calcification both in vivo and in vitro.
Role of Wnt/β-catenin signaling pathway in the mechanism of calcification of aortic valve.
Effects of sodium fluoride treatment in vitro on cell proliferation, BMP-2 and BMP-3 expression in human osteosarcoma MG-63 cells.
Surface functionalization of titanium substrates with cecropin B to improve their cytocompatibility and reduce inflammation responses.
Regulation of Olig2 during astroglial differentiation in the subventricular zone of a cuprizone-induced demyelination mouse model.
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Molecular medicine reports 2019 May;19(5):3469-3476
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Specific knockdown of WNT8b expression protects against phosphate-induced calcification in vascular smooth muscle cells by inhibiting the Wnt-β-catenin signaling pathway.
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Journal of cellular physiology 2019 Apr;234(4):3469-3477
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Bacitracin promotes osteogenic differentiation of human bone marrow mesenchymal stem cells by stimulating the bone morphogenetic protein-2/Smad axis.
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Promotive effects of bone morphogenetic protein 2 on angiogenesis in hepatocarcinoma via multiple signal pathways.
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Scientific reports 2016 Nov 25;6:37499
Metformin alleviates vascular calcification induced by vitamin D3 plus nicotine in rats via the AMPK pathway.
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Overexpression of c1q/tumor necrosis factor-related protein-3 promotes phosphate-induced vascular smooth muscle cell calcification both in vivo and in vitro.
Zhou Y, Wang JY, Feng H, Wang C, Li L, Wu D, Lei H, Li H, Wu LL
Arteriosclerosis, thrombosis, and vascular biology 2014 May;34(5):1002-10
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Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2014 Feb;34(1):33-36
Effects of sodium fluoride treatment in vitro on cell proliferation, BMP-2 and BMP-3 expression in human osteosarcoma MG-63 cells.
Wei Y, Wu Y, Zeng B, Zhang H
Biological trace element research 2014 Dec;162(1-3):18-25
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Surface functionalization of titanium substrates with cecropin B to improve their cytocompatibility and reduce inflammation responses.
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Chen LP, Li ZF, Ping M, Li R, Liu J, Xie XH, Song XJ, Guo L
Neuroscience 2012 Sep 27;221:96-107
Neuroscience 2012 Sep 27;221:96-107
Construction of a eukaryotic expression vector pEGFP-C1-BMP-2 and its effect on cell migration.
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Journal of Zhejiang University. Science. B 2012 May;13(5):356-63
Journal of Zhejiang University. Science. B 2012 May;13(5):356-63
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 18933-1-AP(BMP2 antibody) at dilution of 1:1000
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HT-1080 cells were subjected to SDS PAGE followed by western blot with 18933-1-AP(BMP2 antibody) at dilution of 1:1000
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Sp2/0 cells were subjected to SDS PAGE followed by western blot with 18933-1-AP(BMP2 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The BMP2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human BMP2. This antibody recognizes human,mouse,rat,pig antigen. The BMP2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.