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Protein structure
BMP2
Bone morphogenetic protein 2BMP2A
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016]
Top validated antibodies |
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| Invitrogen Antibodies |  PA5-85956 |
1 references | Polyclonal |
WB
ICC
IHC
FC
OA
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| Proteintech Group | 18933-1-AP |
39 references | Polyclonal |
WB
EL
IHC
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| Novus Biologicals | H00000650-M02 |
2 references | Monoclonal |
WB
EL
ICC
IHC
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| OriGene | PP1219P1 |
1 references | Polyclonal |
WB
EL
IHC
FA
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| GeneTex | GTX14933 |
Polyclonal |
WB
EL
ICC
IP
IHC
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