RA0447

antibody from Oursmab

Targeting: KLKB1 KLK3

Western blot (Supportive data in Antibodypedia)

ELISA (Supportive data in Antibodypedia)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0447

Provider

Oursmab

Product name

Lanadelumab (Biosimilar Reference Antibody) (KLKB1)

Antibody type

Monoclonal

Description

Lanadelumab is a humanized monoclonal antibody that specifically inhibits plasma kallikrein, a key enzyme in the contact system. By blocking kallikrein, it prevents excessive bradykinin production, which is the primary mediator of swelling attacks in hereditary angioedema (HAE). It is approved as a long-term prophylactic treatment to reduce the frequency of HAE attacks.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

Western blot

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

Lanadelumab (Biosimilar Reference Antibody) (KLKB1)-RA0447-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.

ELISA

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

ELISA plate pre-coated Antigen protein, can bind Lanadelumab (Biosimilar Reference Antibody) (KLKB1)-RA0447 in a linear range of 3.91¨C125 ng/mL.