AP31529SU-N

antibody from Acris Antibodies GmbH

Targeting: SERPINF2 A2AP, AAP, ALPHA-2-PI, API, PLI

Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

AP31529SU-N

Provider

Acris Antibodies GmbH

Proper citation

Acris Antibodies GmbH Cat#AP31529SU-N, RRID:AB_10975539

Product name

anti Alpha-2-antiplasmin / SERPINF2

Antibody type

Polyclonal

Antigen

Apha-2 antiplasmin is a single-chain glycoprotein with a molecular weight of about 65,000. The normal concentration in human plasma is 60 μg/ml. Platelets contain significant amounts of the protein, which is released along with platelet factor 4, following thrombin stimulation. It can form 1:1 complexes with circulating plasmin. Alpha-2 antiplasmin is the most important inhibitor of plasmin-mediated fibrinolysis, but also capable of inactivating factor XIIa, kallikrein, factor XIa, thrombin and factor Xa. The importance of the alpha-2 antiplasmin as regulator of the fibrinolytic system was detected by the discovery of a congenital deficiency. Alpha-2 antiplasmin has been isolated from pooled plasma. Freund’s complete adjuvant is used in the first step of the immunization procedure.

Reactivity

Human

Host

Goat

Vial size

1 ml