Tissue expression
Cell line expression
SERPINF2
gene productA2AP, AAP, ALPHA-2-PI, API, PLI
This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Featured antibodies
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0 references | Polyclonal |
WB
ICC IHC
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