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UBE2L3
Ubiquitin conjugating enzyme E2 L3UBCH7
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009]
Top validated antibodies |
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| GeneTex |  GTX104717 |
2 references | Polyclonal |
WB
ICC
IP
IHC
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| Novus Biologicals | NB100-2265 |
1 references | Polyclonal |
WB
ICC
IP
IHC
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| antibodies-online | ABIN552694 |
Polyclonal |
WB
EL
ICC
IP
IHC
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| OriGene | TA308758 |
Polyclonal |
WB
ICC
IP
IHC
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| Proteintech Group | 14415-1-AP |
2 references | Polyclonal |
WB
EL
IP
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