Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
UBE2L3
Ubiquitin conjugating enzyme E2 L3UBCH7
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009]
Top validated antibodies |
|||||
| GeneTex |  GTX104717 |
2 references | Polyclonal |
WB
ICC
IP
IHC
|
|
| Novus Biologicals | NB100-2265 |
1 references | Polyclonal |
WB
ICC
IP
IHC
|
|
| antibodies-online | ABIN552694 |
Polyclonal |
WB
EL
ICC
IP
IHC
|
||
| Proteintech Group | 14415-1-AP |
9 references | Polyclonal |
WB
EL
IP
|
|
| LSBio | LS-C185647 |
Polyclonal |
WB
ICC
IHC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider