ABIN183871

antibody from antibodies-online

Targeting: UBE2L3 UBCH7

Western blot (Data presented on provider website)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN183871

Provider

antibodies-online

Product name

anti-Aprataxin (APTX) (C-Term) antibody

Antibody type

Polyclonal

Antigen

The immunogen for anti-APTX antibody: synthetic peptide directed towards the C terminal of human APTX

Description

Protein A purified

Reactivity

Human, Mouse, Rat, Bovine, Canine, Chicken/Avian, Porcine, Xenopus

Host

Rabbit

Antigen sequence

VIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLP
SIPQL KEHLRKHWTQ


Epitope

C-Term

Vial size

100 μg

Concentration

1mg/mL

Storage

-20°C

Handling

Avoid repeated freeze-thaw cycles.

References

Submitted references

Aprataxin tumor levels predict response of colorectal cancer patients to irinotecan-based treatment.

Dopeso H, Mateo-Lozano S, Elez E, Landolfi S, Ramos Pascual FJ, Hernández-Losa J, Mazzolini R, Rodrigues P, Bazzocco S, Carreras MJ, Espín E, Armengol M, Wilson AJ, Mariadason JM, Ramon Y Cajal S, Tabernero J, Schwartz S Jr, Arango D
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Apr 15;16(8):2375-82

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XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining.

Ahnesorg P, Smith P, Jackson SP
Cell 2006 Jan 27;124(2):301-13