FNab03084

antibody from FineTest Biotech

Targeting: FGB

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

FNab03084

Provider

FineTest Biotech

Product name

FGB antibody

Antibody type

Monoclonal

Antigen

Recombinant protein fragment

Description

Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha(FGA) and fibrinogen gamma(FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Antigen sequence

fibrinogen beta chain


Epitope

IgG2a

Isotype

IgG

Antibody clone number

6F4

Vial size

100¦Ìg

Concentration

Protein A+G purification

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

Handling

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)