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- References [21]
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- Immunohistochemistry [2]
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- Product number
- 16747-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16747-1-AP, RRID:AB_11042764
- Product name
- Fibrinogen Beta Chain antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Fibrinogen Beta Chain antibody (Cat. #16747-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Gancao decoction ameliorated senecionine-induced Hepatic Sinusoidal Obstruction Syndrome in mice by inhibiting NET formation and senecionine bioactivation in liver.
Role of biliverdin reductase, a heme degradation pathway enzyme, in the development of vasospasm after subarachnoid hemorrhage.
Oral efficacy of structurally defined chondroitin sulfate Co-administered with SNAC in Parkinson's disease.
Tissue transglutaminase drives fibrin β-chain cross-linking: a novel fibrin modification observed in patients with trauma.
Complement activation and fibrinolysis dysregulation drive contrast-induced acute kidney injury: a 4D proteomics rat study.
Quantitative proteomic and glycoproteomic analysis identifies CLCA1, FBN1, and FGB as potential biomarkers for ulcerative colitis.
Protein Secretion From Liver Ex Vivo Reveals Regulation of Hepatokines by Sex and Circadian Rhythm.
Growth differentiation factor 11 attenuates sepsis-associated acute kidney injury by reducing inflammation and coagulation via PGC-1α/Nrf2 activation.
Regulation of hepatic inclusions and fibrinogen biogenesis by SEL1L-HRD1 ERAD.
Coagulation factor XIII is a critical driver of liver regeneration after partial hepatectomy.
Plasminogen deficiency suppresses pancreatic ductal adenocarcinoma disease progression.
The β-Chain Mutation p.Arg17Stop Impairs Fibrinogen Synthesis and Secretion: A Nonsense Mutation Associated With Hypofibrinogenemia.
Circ_16601 facilitates Hippo pathway signaling via the miR-5580-5p/FGB axis to promote my-CAF recruitment in the TME and LUAD progression.
Comparative Proteomics Reveals Prolonged Corneal Preservation Impaired Ocular Surface Immunity Accompanied by Fibrosis in Human Stroma.
Characterization of lncRNA functioning in ovine conceptuses and endometria during the peri-implantation period.
Accelerated accumulation of fibrinogen peptide chains with Aβ deposition in Alzheimer's disease (AD) mice and human AD brains.
Formation of fibrin at sights of conceptus adhesion in the ewe.
Clinical application of a new latex photometric immunoassay reagent, LPIA-GENESIS D-dimer, and its performance in patient-derived plasma samples.
The malaria parasite Plasmodium falciparum in red blood cells selectively takes up serum proteins that affect host pathogenicity.
Fibrinogen Chains Intrinsic to the Brain.
Fibrinogen β-derived Bβ(15-42) peptide protects against kidney ischemia/reperfusion injury.
Zhang S, Yan D, Cheng S, Jin J, Cui J, Liu C, Li Y, Qiu F
Journal of ethnopharmacology 2026 May 10;362:121356
Journal of ethnopharmacology 2026 May 10;362:121356
Role of biliverdin reductase, a heme degradation pathway enzyme, in the development of vasospasm after subarachnoid hemorrhage.
Hasanpour-Segherlou Z, Hutchinson H, Xu H, Amini S, Klaas E, Martinez ME, Lucke-Wold B, Hosaka K, Hoh B
Journal of neurointerventional surgery 2026 Mar 13;18(4):1042-1048
Journal of neurointerventional surgery 2026 Mar 13;18(4):1042-1048
Oral efficacy of structurally defined chondroitin sulfate Co-administered with SNAC in Parkinson's disease.
Guo Y, Zhang B, Bu C, An Z, Shi D, Jin L, Sheng A, Zhen A, Chi L
Carbohydrate polymers 2026 Jan 1;371:124492
Carbohydrate polymers 2026 Jan 1;371:124492
Tissue transglutaminase drives fibrin β-chain cross-linking: a novel fibrin modification observed in patients with trauma.
Boateng NKK, Wimberley R, Rose J, D'Alessandro A, Cohen M, Moore E, Schmitt L, Poole L, Luyendyk J, Hansen K
Blood 2026 Jan 1;147(1):87-92
Blood 2026 Jan 1;147(1):87-92
Complement activation and fibrinolysis dysregulation drive contrast-induced acute kidney injury: a 4D proteomics rat study.
Yang Q, Sun L, Zhang Z, Yan Z, Zhang J, Hu J, Ding X
Renal failure 2026 Dec;48(1):2650263
Renal failure 2026 Dec;48(1):2650263
Quantitative proteomic and glycoproteomic analysis identifies CLCA1, FBN1, and FGB as potential biomarkers for ulcerative colitis.
Wang X, Bo S, Li Q, Li W, Xu L, Hu D, Yang S
RSC advances 2025 Oct 8;15(45):38044-38055
RSC advances 2025 Oct 8;15(45):38044-38055
Protein Secretion From Liver Ex Vivo Reveals Regulation of Hepatokines by Sex and Circadian Rhythm.
Litwin C, Zhang Q, Li Z, Hernandez S, Keating M, Sato T, Sassone-Corsi P, Bieniek KF, Koronowski KB
bioRxiv : the preprint server for biology 2025 Mar 1;
bioRxiv : the preprint server for biology 2025 Mar 1;
Growth differentiation factor 11 attenuates sepsis-associated acute kidney injury by reducing inflammation and coagulation via PGC-1α/Nrf2 activation.
Wang HW, Wu MM, Zhu MM, Qin YY, Wang KQ, Wu CY, Zhang RR, Wang Y, Zhou C, Luo S, Lu CS, Pan JY
Cellular & molecular biology letters 2025 Aug 28;30(1):102
Cellular & molecular biology letters 2025 Aug 28;30(1):102
Regulation of hepatic inclusions and fibrinogen biogenesis by SEL1L-HRD1 ERAD.
Song Z, Thepsuwan P, Hur WS, Torres M, Wu SA, Wei X, Tushi NJ, Wei J, Ferraresso F, Paton AW, Paton JC, Zheng Z, Zhang K, Fang D, Kastrup CJ, Jaiman S, Flick MJ, Sun S
Nature communications 2024 Oct 26;15(1):9244
Nature communications 2024 Oct 26;15(1):9244
Coagulation factor XIII is a critical driver of liver regeneration after partial hepatectomy.
Wei Z, Groeneveld DJ, Adelmeijer J, Poole LG, Cline H, Kern AE, Langer B, Brunnthaler L, Assinger A, Starlinger P, Lisman T, Luyendyk JP
Journal of thrombosis and haemostasis : JTH 2024 Mar;22(3):620-632
Journal of thrombosis and haemostasis : JTH 2024 Mar;22(3):620-632
Plasminogen deficiency suppresses pancreatic ductal adenocarcinoma disease progression.
Chowdhury NN, Yang Y, Dutta A, Luo M, Wei Z, Abrahams SR, Revenko AS, Shah F, Miles LA, Parmer RJ, de Laat B, Wolberg AS, Luyendyk JP, Fishel ML, Flick MJ
Molecular oncology 2024 Jan;18(1):113-135
Molecular oncology 2024 Jan;18(1):113-135
The β-Chain Mutation p.Arg17Stop Impairs Fibrinogen Synthesis and Secretion: A Nonsense Mutation Associated With Hypofibrinogenemia.
Qian C, Huang C, Luo Q, Qin K, Wu Y, Liao L, Zhang Q, Xiang L, Yan J
Journal of clinical laboratory analysis 2024 Dec;38(24):e25123
Journal of clinical laboratory analysis 2024 Dec;38(24):e25123
Circ_16601 facilitates Hippo pathway signaling via the miR-5580-5p/FGB axis to promote my-CAF recruitment in the TME and LUAD progression.
Zhou J, Li P, Zhao X, Zhao Y, Luo J, Deng Y, Jiang N, Xiao Z, Zhang W, Zhou Y, Zhao J, Li P, Li Y, Tian Z
Respiratory research 2023 Nov 12;24(1):276
Respiratory research 2023 Nov 12;24(1):276
Comparative Proteomics Reveals Prolonged Corneal Preservation Impaired Ocular Surface Immunity Accompanied by Fibrosis in Human Stroma.
Wu PS, Liu HY, Wong TH, Lin JT, Hu FR, Lin MH
Journal of proteome research 2023 Dec 1;22(12):3730-3741
Journal of proteome research 2023 Dec 1;22(12):3730-3741
Characterization of lncRNA functioning in ovine conceptuses and endometria during the peri-implantation period.
Matsuno Y, Kusama K, Imakawa K
Biochemical and biophysical research communications 2022 Feb 26;594:22-30
Biochemical and biophysical research communications 2022 Feb 26;594:22-30
Accelerated accumulation of fibrinogen peptide chains with Aβ deposition in Alzheimer's disease (AD) mice and human AD brains.
Bian Z, Yamashita T, Shi X, Feng T, Yu H, Hu X, Hu X, Bian Y, Sun H, Tadokoro K, Takemoto M, Omote Y, Morihara R, Abe K
Brain research 2021 Sep 15;1767:147569
Brain research 2021 Sep 15;1767:147569
Formation of fibrin at sights of conceptus adhesion in the ewe.
Matsuno Y, Amin YA, Kusama K, Imakawa K
Reproduction (Cambridge, England) 2021 May 10;161(6):709-720
Reproduction (Cambridge, England) 2021 May 10;161(6):709-720
Clinical application of a new latex photometric immunoassay reagent, LPIA-GENESIS D-dimer, and its performance in patient-derived plasma samples.
Nagahama Y, Nozaki J, Sakurai G, Yajima S, Kaneko N, Yamazaki E, Matsuda M
International journal of laboratory hematology 2020 Jun;42(3):299-307
International journal of laboratory hematology 2020 Jun;42(3):299-307
The malaria parasite Plasmodium falciparum in red blood cells selectively takes up serum proteins that affect host pathogenicity.
Tougan T, Edula JR, Morita M, Takashima E, Honma H, Tsuboi T, Horii T
Malaria journal 2020 Apr 15;19(1):155
Malaria journal 2020 Apr 15;19(1):155
Fibrinogen Chains Intrinsic to the Brain.
Golanov EV, Sharpe MA, Regnier-Golanov AS, Del Zoppo GJ, Baskin DS, Britz GW
Frontiers in neuroscience 2019;13:541
Frontiers in neuroscience 2019;13:541
Fibrinogen β-derived Bβ(15-42) peptide protects against kidney ischemia/reperfusion injury.
Krishnamoorthy A, Ajay AK, Hoffmann D, Kim TM, Ramirez V, Campanholle G, Bobadilla NA, Waikar SS, Vaidya VS
Blood 2011 Aug 18;118(7):1934-42
Blood 2011 Aug 18;118(7):1934-42
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse heart tissue were subjected to SDS PAGE followed by western blot with 16747-1-AP(FGB antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 16747-1-AP(FGB antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Fibrinogen beta chain antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Fibrinogen beta chain. This antibody recognizes human,mouse,rat antigen. The Fibrinogen beta chain antibody has been validated for the following applications: ELISA, WB, IHC analysis.
