Tissue expression
Cell line expression
Protein structure

A2M

Alpha-2-macroglobulin
CPAMD5, FWP007, S863-7 
The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016]
More gene data

All Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antigen sequence

Epitope

Antibody

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
1029 antibodies from 43 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
4 antibodies
Invitrogen Antibodies
54 antibodies
R&D Systems
4 antibodies
Novus Biologicals
34 antibodies
NovoPro Bioscience Inc.
2 antibodies
OriGene
13 antibodies
Biorbyt
93 antibodies
GeneTex
13 antibodies
Wuhan Fine Biotech Co., Ltd.
3 antibodies
Abnova Corporation
14 antibodies
Atlas Antibodies
1 antibody
antibodies-online
263 antibodies
St John's Laboratory
6 antibodies
HUABIO Research
5 antibodies
Cusabio Biotech Co., Ltd
7 antibodies
Rockland Immunochemicals, Inc.
10 antibodies
Affinity Biosciences
2 antibodies
Everest Biotech
1 antibody
Santa Cruz Biotechnology
1 antibody
Acris Antibodies GmbH
26 antibodies
Aviva Systems Biology
7 antibodies
Bioworld Technology, Inc
2 antibodies
Boster Biological Technology
3 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Creative Biolabs
40 antibodies
Antibodies.com
1 antibody
Cell Signaling Technology, Inc
1 antibody
NSJ Bioreagents
4 antibodies
MyBioSource
26 antibodies
Abgent
6 antibodies
RayBiotech, Inc.
4 antibodies
RabMAbs
5 antibodies
GenWay
16 antibodies
Abbexa
14 antibodies
Leading Biology
6 antibodies
ProSci
5 antibodies
MilliporeSigma / Merck KGaA
4 antibodies
United States Biological
79 antibodies
Creative Diagnostics
9 antibodies
Green Mountain Antibodies
1 antibody
Exalpha Biologicals, Inc.
1 antibody