MAB775

antibody from Novus Biologicals

Targeting: IGFBP3 BP-53, IBP3

Western blot (Data presented on provider website)

Antibody Data

Product number

MAB775

Provider

Novus Biologicals

Product name

Rat Monoclonal IGFBP-3 Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects mouse IGFBP-3 in direct ELISAs and Western blots. In Western blots, this antibody does not cross-react with recombinant human IGFBP-1, rhIGFBP-2, rhIGFBP-3, rhIGFBP-4, rhIGFBP-5, rhIGFBP-6, recombinant mouse (rm) IGFBP-2, rmIGFBP-5, or rmIGFBP-6.

Reactivity

Mouse

Host

Rat

Isotype

IgG

Vial size

500 ug

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

References

Submitted references

IGFBP-3 is a metastasis suppression gene in prostate cancer.

Mehta HH, Gao Q, Galet C, Paharkova V, Wan J, Said J, Sohn JJ, Lawson G, Cohen P, Cobb LJ, Lee KW
Cancer research 2011 Aug 1;71(15):5154-63

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Evidence of a role for insulin-like growth factor binding protein (IGFBP)-3 in metabolic regulation.

Yamada PM, Mehta HH, Hwang D, Roos KP, Hevener AL, Lee KW
Endocrinology 2010 Dec;151(12):5741-50

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Dietary feeding of silibinin inhibits prostate tumor growth and progression in transgenic adenocarcinoma of the mouse prostate model.

Raina K, Blouin MJ, Singh RP, Majeed N, Deep G, Varghese L, Glodé LM, Greenberg NM, Hwang D, Cohen P, Pollak MN, Agarwal R
Cancer research 2007 Nov 15;67(22):11083-91

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The ternary IGF complex influences postnatal bone acquisition and the skeletal response to intermittent parathyroid hormone.

Yakar S, Bouxsein ML, Canalis E, Sun H, Glatt V, Gundberg C, Cohen P, Hwang D, Boisclair Y, Leroith D, Rosen CJ
The Journal of endocrinology 2006 May;189(2):289-99