Tissue expression
Cell line expression
Protein structure
IGFBP3
Insulin like growth factor binding protein 3BP-53, IBP3
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | ![]() |
30 references | Polyclonal |
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Novus Biologicals | ![]() |
10 references | Polyclonal |
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R&D Systems | ![]() |
9 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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antibodies-online | ![]() |
1 references | Polyclonal |
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