BAF775

antibody from R&D Systems

Targeting: IGFBP3 BP-53, IBP3

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

BAF775

Provider

R&D Systems

Product name

Mouse IGFBP-3 Biotinylated Antibody

Antibody type

Polyclonal

Description

Antigen Affinity-purified. Detects mouse IGFBP-3 in ELISAs and Western blots. In sandwich ELISAs, less than 0.2% cross-reactivity with recombinant mouse (rm) IGF-I, rmIGF-II, rmIGFBP-2, rmIGFBP-5, rmIGFBP-6, and recombinant human IGFBP-3 is observed.

Reactivity

Mouse

Host

Goat

Conjugate

Biotin

Antigen sequence

P47878


Isotype

IgG

Vial size

50 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

IGFBP-3 is a metastasis suppression gene in prostate cancer.

Mehta HH, Gao Q, Galet C, Paharkova V, Wan J, Said J, Sohn JJ, Lawson G, Cohen P, Cobb LJ, Lee KW
Cancer research 2011 Aug 1;71(15):5154-63

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Evidence of a role for insulin-like growth factor binding protein (IGFBP)-3 in metabolic regulation.

Yamada PM, Mehta HH, Hwang D, Roos KP, Hevener AL, Lee KW
Endocrinology 2010 Dec;151(12):5741-50

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Dietary feeding of silibinin inhibits prostate tumor growth and progression in transgenic adenocarcinoma of the mouse prostate model.

Raina K, Blouin MJ, Singh RP, Majeed N, Deep G, Varghese L, Glodé LM, Greenberg NM, Hwang D, Cohen P, Pollak MN, Agarwal R
Cancer research 2007 Nov 15;67(22):11083-91

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The ternary IGF complex influences postnatal bone acquisition and the skeletal response to intermittent parathyroid hormone.

Yakar S, Bouxsein ML, Canalis E, Sun H, Glatt V, Gundberg C, Cohen P, Hwang D, Boisclair Y, Leroith D, Rosen CJ
The Journal of endocrinology 2006 May;189(2):289-99