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- Antibody Data
- Antigen structure
- References [4]
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- Product number
- MAB775 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse IGFBP-3 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects mouse IGFBP-3 in direct ELISAs and Western blots. In Western blots, this antibody does not cross-react with recombinant human IGFBP-1, rhIGFBP-2, rhIGFBP-3, rhIGFBP-4, rhIGFBP-5, rhIGFBP-6, recombinant mouse (rm) IGFBP-2, rmIGFBP-5, or rmIGFBP-6.
- Reactivity
- Mouse
- Host
- Rat
- Conjugate
- Unconjugated
- Antigen sequence
P47878- Isotype
- IgG
- Antibody clone number
- 138202
- Vial size
- 500 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references IGFBP-3 is a metastasis suppression gene in prostate cancer.
Evidence of a role for insulin-like growth factor binding protein (IGFBP)-3 in metabolic regulation.
Dietary feeding of silibinin inhibits prostate tumor growth and progression in transgenic adenocarcinoma of the mouse prostate model.
The ternary IGF complex influences postnatal bone acquisition and the skeletal response to intermittent parathyroid hormone.
Mehta HH, Gao Q, Galet C, Paharkova V, Wan J, Said J, Sohn JJ, Lawson G, Cohen P, Cobb LJ, Lee KW
Cancer research 2011 Aug 1;71(15):5154-63
Cancer research 2011 Aug 1;71(15):5154-63
Evidence of a role for insulin-like growth factor binding protein (IGFBP)-3 in metabolic regulation.
Yamada PM, Mehta HH, Hwang D, Roos KP, Hevener AL, Lee KW
Endocrinology 2010 Dec;151(12):5741-50
Endocrinology 2010 Dec;151(12):5741-50
Dietary feeding of silibinin inhibits prostate tumor growth and progression in transgenic adenocarcinoma of the mouse prostate model.
Raina K, Blouin MJ, Singh RP, Majeed N, Deep G, Varghese L, Glodé LM, Greenberg NM, Hwang D, Cohen P, Pollak MN, Agarwal R
Cancer research 2007 Nov 15;67(22):11083-91
Cancer research 2007 Nov 15;67(22):11083-91
The ternary IGF complex influences postnatal bone acquisition and the skeletal response to intermittent parathyroid hormone.
Yakar S, Bouxsein ML, Canalis E, Sun H, Glatt V, Gundberg C, Cohen P, Hwang D, Boisclair Y, Leroith D, Rosen CJ
The Journal of endocrinology 2006 May;189(2):289-99
The Journal of endocrinology 2006 May;189(2):289-99
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