Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- MAB305 - Provider product page
- Provider
- R&D Systems
- Product name
- Anti-Human IGFBP-3 Monoclonal Antibody (Clone 84728)
- Antibody type
- Monoclonal
- Antigen
- Mouse myeloma cell line NS0-derived recombinant human IGFBP-3, Gly28-Lys291
- Description
- Protein A or G purified from hybridoma culture supernatant
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
CAA46087
- Isotype
- IgG
- Vial size
- 500 µg
Submitted references The participation of insulin-like growth factor-binding protein 3 released by astrocytes in the pathology of Alzheimer's disease.
IGFBP3 promotes esophageal cancer growth by suppressing oxidative stress in hypoxic tumor microenvironment.
Plasminogen activator inhibitor 1--insulin-like growth factor binding protein 3 cascade regulates stress-induced senescence.
Human IGF binding protein-3 overexpression impairs glucose regulation in mice via an inhibition of insulin secretion.
Epidermal growth factor receptor regulates aberrant expression of insulin-like growth factor-binding protein 3.
Watanabe K, Uemura K, Asada M, Maesako M, Akiyama H, Shimohama S, Takahashi R, Kinoshita A
Molecular brain 2015 Dec 4;8(1):82
Molecular brain 2015 Dec 4;8(1):82
IGFBP3 promotes esophageal cancer growth by suppressing oxidative stress in hypoxic tumor microenvironment.
Natsuizaka M, Kinugasa H, Kagawa S, Whelan KA, Naganuma S, Subramanian H, Chang S, Nakagawa KJ, Rustgi NL, Kita Y, Natsugoe S, Basu D, Gimotty PA, Klein-Szanto AJ, Diehl JA, Nakagawa H
American journal of cancer research 2014;4(1):29-41
American journal of cancer research 2014;4(1):29-41
Plasminogen activator inhibitor 1--insulin-like growth factor binding protein 3 cascade regulates stress-induced senescence.
Elzi DJ, Lai Y, Song M, Hakala K, Weintraub ST, Shiio Y
Proceedings of the National Academy of Sciences of the United States of America 2012 Jul 24;109(30):12052-7
Proceedings of the National Academy of Sciences of the United States of America 2012 Jul 24;109(30):12052-7
Human IGF binding protein-3 overexpression impairs glucose regulation in mice via an inhibition of insulin secretion.
Nguyen KH, Yao XH, Moulik S, Mishra S, Nyomba BL
Endocrinology 2011 Jun;152(6):2184-96
Endocrinology 2011 Jun;152(6):2184-96
Epidermal growth factor receptor regulates aberrant expression of insulin-like growth factor-binding protein 3.
Takaoka M, Harada H, Andl CD, Oyama K, Naomoto Y, Dempsey KL, Klein-Szanto AJ, El-Deiry WS, Grimberg A, Nakagawa H
Cancer research 2004 Nov 1;64(21):7711-23
Cancer research 2004 Nov 1;64(21):7711-23
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