ABIN967345

antibody from antibodies-online

Targeting: CASP12

Western blot (Data presented on provider website)

Antibody Data

Product number

ABIN967345

Provider

antibodies-online

Product name

anti-Caspase 12 (CASP12) (AA 2-17) antibody

Antibody type

Polyclonal

Antigen

Murine Caspase-12 peptide aa. 2-17

Description

The polyclonal antibody was purified from antiserum by negative adsorption and affinity chromatography.

Reactivity

Human, Mouse

Host

Rabbit

Epitope

AA 2-17

Isotype

IgG

Vial size

100 μL

Storage

Store the antibody at 4°C. Store the positive control lysate (Cat. No. 51-16586N) at -20°C.

References

Submitted references

Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress.

Yoneda T, Imaizumi K, Oono K, Yui D, Gomi F, Katayama T, Tohyama M
The Journal of biological chemistry 2001 Apr 27;276(17):13935-40

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta.

Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA, Yuan J
Nature 2000 Jan 6;403(6765):98-103

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Suicidal tendencies: apoptotic cell death by caspase family proteinases.

Wolf BB, Green DR
The Journal of biological chemistry 1999 Jul 16;274(29):20049-52

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Characterization of seven murine caspase family members.

Van de Craen M, Vandenabeele P, Declercq W, Van den Brande I, Van Loo G, Molemans F, Schotte P, Van Criekinge W, Beyaert R, Fiers W
FEBS letters 1997 Feb 10;403(1):61-9