CASP12

gene product
Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Feb 2011]
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553 antibodies from 39 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
151 antibodies
Novus Biologicals
10 antibodies
Biorbyt
39 antibodies
Acris Antibodies GmbH
24 antibodies
OriGene
15 antibodies
Abgent
10 antibodies
NSJ Bioreagents
3 antibodies
Arigo
4 antibodies
LifeSpan BioSciences, Inc.
100 antibodies
Abnova Corporation
9 antibodies
GeneTex
7 antibodies
NovoPro Bioscience Inc.
6 antibodies
Invitrogen Antibodies
8 antibodies
Rockland Immunochemicals, Inc.
5 antibodies
ProSci
8 antibodies
Enzo Life Sciences
2 antibodies
Aviva Systems Biology
1 antibody
Affinity Biosciences
1 antibody
Bioworld Technology, Inc
1 antibody
R&D Systems
1 antibody
Boster Biological Technology
2 antibodies
St John's Laboratory
3 antibodies
Antibodies.com
1 antibody
MyBioSource
10 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Everest Biotech
1 antibody
United States Biological
85 antibodies
ABEOMICS Inc.
2 antibodies
Creative Biolabs
5 antibodies
Creative Diagnostics
6 antibodies
RayBiotech, Inc.
3 antibodies
Abiocode, Inc.
1 antibody
Cell Signaling Technology, Inc
1 antibody
GenWay
3 antibodies
EMD Millipore
2 antibodies
Abbexa
6 antibodies
eBioscience, An Affymetrix Company
2 antibodies
Exalpha Biologicals, Inc.
2 antibodies