ABIN567796

antibody from antibodies-online

Targeting: CASP12

Western blot (Supportive data in Antibodypedia)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

ABIN567796

Provider

antibodies-online

Product name

anti-Caspase 12 (CASP12) (AA 95-318), (N-Term) antibody

Antibody type

Monoclonal

Description

Protein-G Agarose Chromatography of hybridoma supernatant.

Reactivity

Human, Mouse, Rat

Host

Rat

Epitope

N-Term, AA 95-318

Isotype

IgG

Antibody clone number

14F4

Vial size

0.1 mg

Storage

Store the antibody (in aliquots) at -20°C.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12.

Morishima N, Nakanishi K, Takenouchi H, Shibata T, Yasuhiko Y
The Journal of biological chemistry 2002 Sep 13;277(37):34287-94

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta.

Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA, Yuan J
Nature 2000 Jan 6;403(6765):98-103

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Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis.

Nakagawa T, Yuan J
The Journal of cell biology 2000 Aug 21;150(4):887-94

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Immunocytochemistry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Image(s): Immunofluorescence