Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
PON1
Paraoxonase 1ESA, PON
This gene encodes a member of the paraoxonase family of enzymes and exhibits lactonase and ester hydrolase activity. Following synthesis in the kidney and liver, the enzyme is secreted into the circulation, where it binds to high density lipoprotein (HDL) particles and hydrolyzes thiolactones and xenobiotics, including paraoxon, a metabolite of the insecticide parathion. Polymorphisms in this gene may be associated with coronary artery disease and diabetic retinopathy. The gene is found in a cluster of three related paraoxonase genes on chromosome 7. [provided by RefSeq, Aug 2017]
Top validated antibodies |
|||||
| antibodies-online |  ABIN1724910 |
2 references | Monoclonal |
WB
EL
ICC
IHC
FC
|
|
| Invitrogen Antibodies | CF502528 |
Monoclonal |
WB
EL
ICC
IHC
FC
|
||
| OriGene | TA502528 |
Monoclonal |
WB
EL
ICC
IHC
FC
|
||
| Novus Biologicals | NBP2-37307 |
Monoclonal |
WB
EL
IHC
FC
|
||
| LSBio | LS-C337285 |
Monoclonal |
WB
EL
ICC
IHC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider