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Protein structure
MXD1
MAX dimerization protein 1bHLHc58, MAD, MAD1
This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
Top validated antibodies |
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| Proteintech Group |  19547-1-AP |
1 references | Polyclonal |
WB
EL
IP
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| Atlas Antibodies | HPA001599 |
3 references | Polyclonal |
IHC
ChIP
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| Invitrogen Antibodies | 19547-1-AP |
Polyclonal |
WB
IP
OA
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| NovoPro Bioscience Inc. | 112910 |
Polyclonal |
WB
EL
IP
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| Abnova Corporation | PAB28456 |
Polyclonal |
ICC
IHC
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