ABIN356767

antibody from antibodies-online

Targeting: PIAS2 ARIP3, miz, PIASX-ALPHA, PIASX-BETA, ZMIZ4

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN356767

Provider

antibodies-online

Product name

anti-Protein Inhibitor of Activated STAT, 2 (PIAS2) (C-Term) antibody

Antibody type

Polyclonal

Description

Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Reactivity

Human

Host

Rabbit

Epitope

C-Term

Vial size

0.4 mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells.

Sakurai T, Itoh K, Higashitsuji H, Nagao T, Nonoguchi K, Chiba T, Fujita J
The Journal of biological chemistry 2004 Apr 9;279(15):15505-14

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PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4.

Arora T, Liu B, He H, Kim J, Murphy TL, Murphy KM, Modlin RL, Shuai K
The Journal of biological chemistry 2003 Jun 13;278(24):21327-30

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Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter.

Wu S, Cetinkaya C, Munoz-Alonso MJ, von der Lehr N, Bahram F, Beuger V, Eilers M, Leon J, Larsson LG
Oncogene 2003 Jan 23;22(3):351-60

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Inhibition of Stat1-mediated gene activation by PIAS1.

Liu B, Liao J, Rao X, Kushner SA, Chung CD, Chang DD, Shuai K
Proceedings of the National Academy of Sciences of the United States of America 1998 Sep 1;95(18):10626-31

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Miz1, a novel zinc finger transcription factor that interacts with Msx2 and enhances its affinity for DNA.

Wu L, Wu H, Ma L, Sangiorgi F, Wu N, Bell JR, Lyons GE, Maxson R
Mechanisms of development 1997 Jul;65(1-2):3-17