Antibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 14105-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14105-1-AP, RRID:AB_10639523
- Product name
- ARNT,HIF1B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ARNT,HIF1B antibody (Cat. #14105-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Benvitimod Inhibits IL-4- and IL-13-Induced Tight Junction Impairment by Activating AHR/ARNT Pathway and Inhibiting STAT6 Phosphorylation in Human Keratinocytes.
Sustained AhR activity programs memory fate of early effector CD8(+) T cells.
Parkin deficiency promotes liver cancer metastasis by TMEFF1 transcription activation via TGF-β/Smad2/3 pathway.
The Interplay Between HIF-1α and EZH2 in Lung Cancer and Dual-Targeted Drug Therapy.
L-Kynurenine participates in cancer immune evasion by downregulating hypoxic signaling in T lymphocytes.
EPAS1 prevents telomeric damage-induced senescence by enhancing transcription of TRF1, TRF2, and RAD50.
Fine particulate matter (PM2.5) induces inhibitory memory alveolar macrophages through the AhR/IL-33 pathway.
NUPR1 contributes to radiation resistance by maintaining ROS homeostasis via AhR/CYP signal axis in hepatocellular carcinoma.
Induction of estrogen receptor β-mediated autophagy sensitizes breast cancer cells to TAD1822-7, a novel biphenyl urea taspine derivative.
High-fat diet and alcohol induced-mice could cause colonic injury through molecular mechanisms of endogenous toxins.
Induction of aryl hydrocarbon receptor in granulosa cells by endoplasmic reticulum stress contributes to pathology of polycystic ovary syndrome.
Fine Particulate Matter (PM(2).(5)) Promotes CD146 Expression in Alveolar Epithelial Cells and Cryptococcus neoformans Pulmonary Infection.
Tetrandrine enhances the ubiquitination and degradation of Syk through an AhR-c-src-c-Cbl pathway and consequently inhibits osteoclastogenesis and bone destruction in arthritis.
Fine Particulate Matter (PM(2.5)) Promoted the Invasion of Lung Cancer Cells via an ARNT2/PP2A/STAT3/MMP2 Pathway.
Particulate matter 2.5 regulates lipid synthesis and inflammatory cytokine production in human SZ95 sebocytes.
Isorhamnetin Inhibits Reactive Oxygen Species-Dependent Hypoxia Inducible Factor (HIF)-1α Accumulation.
Sestrin2 inhibits hypoxia-inducible factor-1α accumulation via AMPK-mediated prolyl hydroxylase regulation.
Interferon-γ-induced intestinal epithelial barrier dysfunction by NF-κB/HIF-1α pathway.
PROX1 promotes hepatocellular carcinoma metastasis by way of up-regulating hypoxia-inducible factor 1α expression and protein stability.
Wang X, Mao D, Jia J, Zhang J
The Journal of investigative dermatology 2024 Mar;144(3):509-519.e7
The Journal of investigative dermatology 2024 Mar;144(3):509-519.e7
Sustained AhR activity programs memory fate of early effector CD8(+) T cells.
Zhang H, Yang Z, Yuan W, Liu J, Luo X, Zhang Q, Li Y, Chen J, Zhou Y, Lv J, Zhou N, Ma J, Tang K, Huang B
Proceedings of the National Academy of Sciences of the United States of America 2024 Mar 12;121(11):e2317658121
Proceedings of the National Academy of Sciences of the United States of America 2024 Mar 12;121(11):e2317658121
Parkin deficiency promotes liver cancer metastasis by TMEFF1 transcription activation via TGF-β/Smad2/3 pathway.
Su Q, Wang JJ, Ren JY, Wu Q, Chen K, Tu KH, Zhang Y, Leong SW, Sarwar A, Han X, Zhang M, Dai WF, Zhang YM
Acta pharmacologica Sinica 2024 Jul;45(7):1520-1529
Acta pharmacologica Sinica 2024 Jul;45(7):1520-1529
The Interplay Between HIF-1α and EZH2 in Lung Cancer and Dual-Targeted Drug Therapy.
Wang J, Yang C, Xu H, Fan X, Jia L, Du Y, Liu S, Wang W, Zhang J, Zhang Y, Wang X, Liu Z, Bao J, Li S, Yang J, Wu C, Tang J, Chen G, Wang L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2303904
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2303904
L-Kynurenine participates in cancer immune evasion by downregulating hypoxic signaling in T lymphocytes.
Schlichtner S, Yasinska IM, Klenova E, Abooali M, Lall GS, Berger SM, Ruggiero S, Cholewa D, Milošević M, Gibbs BF, Fasler-Kan E, Sumbayev VV
Oncoimmunology 2023;12(1):2244330
Oncoimmunology 2023;12(1):2244330
EPAS1 prevents telomeric damage-induced senescence by enhancing transcription of TRF1, TRF2, and RAD50.
Li KQ, Liu GJ, Liu XY, Chen QF, Huang XY, Tu Q, Zhang J, Chang Q, Xie YH, Hua R, Xu DM, Liu Z, Zhao B
Zoological research 2023 May 18;44(3):636-649
Zoological research 2023 May 18;44(3):636-649
Fine particulate matter (PM2.5) induces inhibitory memory alveolar macrophages through the AhR/IL-33 pathway.
Liu Y, Yuan Q, Zhang X, Chen Z, Jia X, Wang M, Xu T, Wang Z, Jiang J, Ma Q, Zhang M, Huang M, Ji N
Cellular immunology 2023 Apr;386:104694
Cellular immunology 2023 Apr;386:104694
NUPR1 contributes to radiation resistance by maintaining ROS homeostasis via AhR/CYP signal axis in hepatocellular carcinoma.
Zhan Y, Zhang Z, Liu Y, Fang Y, Xie Y, Zheng Y, Li G, Liang L, Ding Y
BMC medicine 2022 Oct 19;20(1):365
BMC medicine 2022 Oct 19;20(1):365
Induction of estrogen receptor β-mediated autophagy sensitizes breast cancer cells to TAD1822-7, a novel biphenyl urea taspine derivative.
Su Q, Wu Q, Chen K, Wang J, Sarwar A, Zhang Y
Molecular biology reports 2022 Feb;49(2):1223-1232
Molecular biology reports 2022 Feb;49(2):1223-1232
High-fat diet and alcohol induced-mice could cause colonic injury through molecular mechanisms of endogenous toxins.
Zhu S, Huang H, Xu S, Liu Y, Wu Y, Xu S, Huang S, Gao J, He L
Toxicology research 2022 Aug;11(4):696-706
Toxicology research 2022 Aug;11(4):696-706
Induction of aryl hydrocarbon receptor in granulosa cells by endoplasmic reticulum stress contributes to pathology of polycystic ovary syndrome.
Kunitomi C, Harada M, Kusamoto A, Azhary JM, Nose E, Koike H, Xu Z, Urata Y, Takahashi N, Wada-Hiraike O, Hirota Y, Koga K, Fujii T, Osuga Y
Molecular human reproduction 2021 Feb 27;27(3)
Molecular human reproduction 2021 Feb 27;27(3)
Fine Particulate Matter (PM(2).(5)) Promotes CD146 Expression in Alveolar Epithelial Cells and Cryptococcus neoformans Pulmonary Infection.
Sun Z, Ji N, Jiang J, Tao Y, Zhang E, Yang X, Wang Z, Chen Z, Huang M, Zhang M
Frontiers in microbiology 2020;11:525976
Frontiers in microbiology 2020;11:525976
Tetrandrine enhances the ubiquitination and degradation of Syk through an AhR-c-src-c-Cbl pathway and consequently inhibits osteoclastogenesis and bone destruction in arthritis.
Jia Y, Tao Y, Lv C, Xia Y, Wei Z, Dai Y
Cell death & disease 2019 Jan 15;10(2):38
Cell death & disease 2019 Jan 15;10(2):38
Fine Particulate Matter (PM(2.5)) Promoted the Invasion of Lung Cancer Cells via an ARNT2/PP2A/STAT3/MMP2 Pathway.
Chen Z, Ji N, Wang Z, Wu C, Sun Z, Li Y, Hu F, Wang Z, Huang M, Zhang M
Journal of biomedical nanotechnology 2018 Dec 1;14(12):2172-2184
Journal of biomedical nanotechnology 2018 Dec 1;14(12):2172-2184
Particulate matter 2.5 regulates lipid synthesis and inflammatory cytokine production in human SZ95 sebocytes.
Liu Q, Wu J, Song J, Liang P, Zheng K, Xiao G, Liu L, Zouboulis CC, Lei T
International journal of molecular medicine 2017 Oct;40(4):1029-1036
International journal of molecular medicine 2017 Oct;40(4):1029-1036
Isorhamnetin Inhibits Reactive Oxygen Species-Dependent Hypoxia Inducible Factor (HIF)-1α Accumulation.
Seo S, Seo K, Ki SH, Shin SM
Biological & pharmaceutical bulletin 2016;39(11):1830-1838
Biological & pharmaceutical bulletin 2016;39(11):1830-1838
Sestrin2 inhibits hypoxia-inducible factor-1α accumulation via AMPK-mediated prolyl hydroxylase regulation.
Seo K, Seo S, Ki SH, Shin SM
Free radical biology & medicine 2016 Dec;101:511-523
Free radical biology & medicine 2016 Dec;101:511-523
Interferon-γ-induced intestinal epithelial barrier dysfunction by NF-κB/HIF-1α pathway.
Yang S, Yu M, Sun L, Xiao W, Yang X, Sun L, Zhang C, Ma Y, Yang H, Liu Y, Lu D, Teitelbaum DH, Yang H
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2014 Mar;34(3):195-203
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2014 Mar;34(3):195-203
PROX1 promotes hepatocellular carcinoma metastasis by way of up-regulating hypoxia-inducible factor 1α expression and protein stability.
Liu Y, Zhang JB, Qin Y, Wang W, Wei L, Teng Y, Guo L, Zhang B, Lin Z, Liu J, Ren ZG, Ye QH, Xie Y
Hepatology (Baltimore, Md.) 2013 Aug;58(2):692-705
Hepatology (Baltimore, Md.) 2013 Aug;58(2):692-705
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ARNT,HIF1B antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ARNT,HIF1B. This antibody recognizes human, mouse antigen. The ARNT,HIF1B antibody has been validated for the following applications: ELISA, WB analysis.