Tissue expression
Cell line expression
Protein structure
ARNT
Aryl hydrocarbon receptor nuclear translocatorbHLHe2, HIF-1beta
This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]
Top validated antibodies |
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Novus Biologicals | NB100-110 | 52 references | Polyclonal |
WB
ICC
IP
IHC
GS
ChIP |
|
GeneTex | GTX22771 | 7 references | Monoclonal |
WB
ICC
IP
IHC
GS
|
|
Invitrogen Antibodies | MA1-515 | 23 references | Monoclonal |
WB
ICC
IP
IHC
GS
OA |
|
antibodies-online | ABIN394250 | 5 references | Monoclonal |
WB
EL
ICC
IHC |
|
OriGene | TA501147 | 1 references | Monoclonal |
WB
ICC
IHC
FC |
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Supportive data in Antibodypedia
Data presented on provider website
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Recommended by provider